Cannabidiol

Known as an antibacterial, Inhibits Cancer cell growth, is Neuroprotective, promotes bone growth, reduces seizures and convulsions, reduces blood sugar levels, reduces function in the immune system, reduces the risk of artery blockage, reduces small intestine contractions, reduces vomiting and nausea, relieves pain, relieves anxiety, slows bacterial growth, suppresses muscle spasms, tranquilizing, treats Psoriasis.

CBD, or cannabidiol, is a non-intoxicating compound found in cannabis and hemp. CBD oils, tinctures, aerosols, topicals and other products are continuing to grow in popularity as ways to manage anxiety, stress, pain, and other symptoms.

It's somewhat typical to associate cannabis with getting stoned, but CBD can be extracted from the plant to make products that come without the high or the smoke. The molecule in cannabis that gets us high is called THC (tetrahydrocannabinol), and nowadays, you can turn to cannabis-derived CBD products with little to no THC for clear-headed symptom relief.

It’s not just THC and CBD, either—cannabis produces dozens of potentially therapeutic compounds called cannabinoids. We’re slowly getting to know them as legalization spreads, and so far, they seem pretty friendly to us humans and our many ailments.

Source: Monarch Life Sciences

Cannabidiolic acid

While most cannabinoids bind directly with either the CB1 or CB2 receptors, CBDA doesn’t work in this way. Instead, CBDA interacts with the endocannabinoid system by inhibiting the cyclooxygenase-2 (COX-2) enzyme. COX-2 enzymes are associated with inflammation after an injury or infection, so by blocking COX-2 enzymes, CBDA can relieve inflammation and associated pain.

In one rodent study, scientists found CBDA affected levels of serotonin, a chemical produced by nerve cells to aid in signaling between cells. Serotonin is vital to core human functions like motor skills, sleeping, eating, digestion, and emotions.

A number of stressors, including radiation and chemotherapy, trigger the body to release excess serotonin, causing nausea and vomiting. While vomiting can typically be controlled with medication, nausea is harder to control. Many cancer patients say that nausea causes much more distress than vomiting because nausea is a continuous sensation. In fact, one in five patients consider discontinuing cancer treatment so as to not experience the nausea.

Scientists have demonstrated that CBDA can affect the body’s 5-HT serotonin-producing receptors, hinting at a potential use for CBDA as a medication for chemotherapy-induced nausea/vomiting (CINV) and other conditions that induce these symptoms. However, more research is needed.

Source: Leafly
 

Cannabichromene

Known for relieving pain, reducing inflammation, promoting bone growth, and inhibiting cancer cell growth

CBC is non-intoxicating, so it doesn’t produce a euphoric high like THC. The reason it is non-intoxicating is because it binds poorly to CB1 cannabinoid receptors in the brain. But CBC does bind with other receptors in the body, such as the vanilloid receptor 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1), both of which are linked to pain perception. When CBC activates these receptors, increased levels of the body’s natural endocannabinoids like anandamide are released.

While CBC definitely has singular benefits, researchers also think that it seems to synergistically work with other cannabinoids, a term known as the entourage effect. This effect of THC and CBD working together is well-known, but whether other cannabinoids have entourage effects is not well understood.

Source: Monarch Life Sciences

Delta-9 Tetrahydrocannabinol

Known for Reducing Vomiting and Nausea, Suppresses Muscle Spasms, Stimulates Appetite, Relieves Pain

Most people know that THC, or tetrahydrocannabinol, is the chemical compound in cannabis responsible for a euphoric high. What more is there to know about cannabis’ primary psychoactive component? Whether the question comes as a newbie to the cannabis world or an experienced consumer who would like to know a bit more about the most famous of cannabinoids, THC has likely been synonymous with cannabis in your mind for as long as you’ve known about the plant.

The first step to understanding THC is to understand cannabinoids. Cannabinoids are chemical compounds found in the cannabis plant that interact with receptors in the brain and body to create various effects. There exist dozens, and potentially more than 100, cannabinoids in the cannabis plant, but THC is most widely known among these due to its abundance and euphoric attributes.

Source: Monarch Life Sciences

Delta-8 Tetrahydrocannabinol

Known for Pain Relief

Delta-8-THC, one of the four most common cannabinoids, is similar to its psychoactive relative THC, but with several key differences.

Delta-8-THC is chemically different from delta-9-THC by only a few atomic bonds and still offers a potent high of its own. While delta-8-THC only exists naturally in fractions of a percent, companies are finding value in concentrating esoteric cannabinoids for their unique effects and applications.

Source: Monarch Life Sciences