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https://hightimes.com/

Bernie Sanders Demands Probe of Proposal To Patent Taxpayer-Funded Cancer Drug

Sen. Bernie Sanders is once again keeping drug makers in check, suggesting that people living with cancer are being preyed on by greedy interests. On Monday, Sanders demanded a Department of Health-led investigation into a proposal to grant a company with an exclusive patent license for cancer treatment and methods, produced with public resources and a potential conflict of interest. The sexually transmitted infection Human papillomavirus (HPV) can lead to six types of cancer and most cervical cancer, the National Cancer Institute (NCI) reports. It can be dormant for years or cause genital warts or worse. Last month, National Institutes of Health (NIH) proposed granting Kingston, New Jersey-based Scarlet TCR a patent for a T-cell therapy for HPV, which has undergone a Phase I trial and has a Phase II trial scheduled to conclude in 2025. There’s no cure for HPV, but drug developers are examining T-cell therapies to combat HPV and the cancers it leads to, including Scarlet TCR. Sometimes they’re gene-engineered. (CBD is also being explored for its potential to inhibit cervical cancer cells.)  There’s a problem though. The patent proposal and the company’s ties to an ex-government employee and other inconsistencies were revealed in an Oct. 18 report by The American Prospect. The NIH quietly applied to be granted “an exclusive patent for a cancer drug, potentially worth hundreds of millions or even billions of dollars, to an obscure company staffed by one of its former employees,” The American Prospect reports. Sanders, chairman of the Senate Health, Education, Labor, and Pensions (HELP) Committee, demanded a probe of the patent proposal in an Oct. 23 letter to Christi Grimm, who is inspector general of the U.S. Department of Health and Human Services. The HELP committee also announced Sander’s open letter on Oct. 23. Sanders suggested the NIH is allowing a company to take advantage of a life-saving cancer drug. “I am growing increasingly alarmed that not only has the NIH abdicated its authority to ensure that the new drugs it helps develop are reasonably priced, it may actually be exceeding its authority to grant monopoly licenses to pharmaceutical companies that charge the American people, by far, the highest prices in the world for prescription drugs,” Sanders wrote. “One particularly egregious example has recently been brought to my attention that I believe demands your immediate attention.” Sanders argued that the NIH should be doing more to lower the cost of drug therapy. “There does not appear to be anything reasonable and necessary about granting a monopoly for a treatment that was invented, manufactured and tested by the NIH, is already in late stage trials and could potentially enrich a former NIH employee who was one of the major government researchers of this treatment,” Sanders wrote. “Based on current law and the best interest of U.S. taxpayers who paid for this cancer therapy, it would seem to make more sense for the NIH to offer non-exclusive licenses so that multiple manufacturers can produce this important cancer therapy at reasonable and affordable prices. The apparent abuse of the system by the NIH with respect to the exclusive patent license for this cancer therapy is so egregious that it has been characterized as a ‘how-to-become-a-billionaire program run by the NIH.’” “If accurate,” Sanders wrote, “that would be absolutely unacceptable. The NIH should be doing everything within its authority to lower the outrageously high price of prescription drugs. It should not be granting a monopoly on a promising taxpayer-funded therapy that could cost hundreds of thousands of dollars for cancer patients in a way that appears to exceed its statutory authority.” The American Prospect story pointed out that the NIH offering an exclusive license for a cancer treatment to a company with no website or SEC filings staffed by a former NIH employee There is historical precedence on life-saving drugs or therapies that didn’t need a patent: On Jan. 23, 1923, Sir Frederick G. Banting, James B. Collip, and Charles Best, discoverers of insulin, were awarded U.S. patents on insulin and the methods used. They all sold these patents to the University of Toronto for $1 each. Banting said, “Insulin does not belong to me, it belongs to the world.”  While things have changed and the price of insulin skyrocketed, new efforts are being made by the drug’s top three makers to make insulin affordable once again. When the polio vaccine was found to be 90% effective, its discoverer wasn’t in it for the money. On April 12, 1955, Edward R. Murrow asked Jonas Salk who owned the patent to the polio vaccine. “Well, the people, I would say,” Salk responded. “There is no patent. Could you patent the sun?” In today’s pharmaceutical world, some of those values are lost.

https://hightimes.com/

Oregon Cannabis Industry Groups Merge Amid Market Downturn

Two cannabis industry groups in Oregon have decided to join forces in a merger that comes amid a downturn in the state’s market for legal marijuana. The two groups, the Oregon Cannabis Association and the Cannabis Industry Alliance of Oregon, announced the merger last week following unanimous votes by the boards of directors of each organization. The newly merged group is named the Cannabis Industry Alliance of Oregon and represents more than 500 member businesses in the state’s licensed cannabis industry, which generates nearly $1 billion in regulated sales per year. “There’s a lot of knowledge, there’s a lot of passion, there’s a lot of really educated folks within the cannabis industry in Oregon,” said Hunter Neubauer, board member of the combined trade group. “Those folks need one place to go to, where they can take a little bit of money that they have, and hopefully become members, and show up with us in Salem and advocate for reasonable regulations and future opportunities for the industry.” Oregon legalized medical marijuana in 1998 through a ballot initiative that received more than 54% of the vote. That was followed by the legalization of adult-use cannabis in 2014, the same year the Oregon Cannabis Association was founded to serve as a lobbying and networking group for the state’s cannabis businesses. The Cannabis Industry Alliance was formed in 2022 through a separate merger of three groups representing regulated cannabis industry retailers and cultivators.  “It’s a community that we all really value and we want to see survive and thrive,” Mike Getlin, the board chair of the Cannabis Industry Alliance of Oregon, told local media. “We want something more than a bunch of minimum wage jobs owned by out-of-state and potentially even overseas financial interests. So that’s what this fight is really about for us.” Neubauer noted that since the launch of adult-use cannabis nearly a decade ago, the regulated industry has experienced two boom and bust cycles. Currently, an oversupply of recreational marijuana has depressed prices, resulting in the first contraction of the market since legalization.  “The overabundance of supply throughout 2021 and 2022 resulted in historically low wholesale and retail prices for both usable marijuana and concentrate/extract products,” the Oregon Liquor and Cannabis Commission wrote in a report released in February of this year. “The declining prices, in combination with a tempering in the growth of quantities purchased, resulted in the first-ever decrease in annual sales (from $1.2 billion in 2021 to $994 million in 2022).” The oversupply and drop in weed prices at the wholesale and retail levels came at a time of steep inflation throughout the economy as a whole, putting further pressure on operators in the troubled cannabis industry. “It’s been … really tough because as you look at budgets in a really constrained market –less than 30% of businesses are profitable,” said Marianne Cursetjee, owner of Alabi Cannabis. The challenging market has led to the failure of many businesses and the consolidation of others. The owners of the remaining firms hope that the merger of the two trade groups will help align the industry toward common goals. In addition to the troubled market, operators face other challenges including high taxes and regulatory fees as well as competition from a persistent unlicensed industry. “If I look through my phone of all of my close friends and colleagues from 2017, very few are still in business,” said Mike Getlin, the board chair of the Cannabis Industry Alliance of Oregon and a leader at Nectar. “It is more important now than it’s ever been to speak with one unified voice and to work as one unified body with regulators and legislators to try and figure out a way to carve out a better future for our businesses.” Oregon’s troubled cannabis industry has also had to weather the fallout of a scandal surrounding the cannabis brand La Mota earlier this year. According to data reported to the state, the company had failed to pay some taxes and was facing legal action from vendors. With attention on the company, it was revealed that then-Oregon Secretary of State Shemia Fagan had signed a pricey consulting contract with La Mota. Fagan resigned in May in the midst of the scandal, which Neubauer said has led to a rift in communication between the state legislature and the regulated cannabis industry. “It’s been really tough since something’s surfaced surrounding one of the companies in Oregon and Shemia Fagan,” said Neubauer. “Our goal with the merger is to take the industry’s leaders and advocates that are still here and combine our resources so that we can show that was one bad apple.”

https://hightimes.com/

New York Cannabis Office Releases Fact Sheet To Battle Misinformation About Weed, Fentanyl

The New York Office of Cannabis Management (OCM) published a two-page report entitled “Cannabis and Fentanyl: Facts and Unknowns” to demystify the facts and myths of the two substances, specifically that of fentanyl contaminating cannabis. “The goal of this fact sheet is to provide evidence where it is available, to share information about what is currently known and unknown, and to provide safety tips to help alleviate some of these misconceptions, often spread through misinformed media coverage and anecdotal reporting,” the report stated. The report includes multiple key findings. First, that misinformation connected to “cannabis ‘contaminated’ with fentanyl are widespread.” In response to this, and the reason the report was created in the first place, is to disprove and combat that misinformation, stating that “Anecdotal reports of fentanyl ‘contaminated’ cannabis continue to be found to be false, as of the date of this publication.” The OCM also added that due to the stigma that opioid consumers experience in health care settings, they develop mistrust that leads to inaccurate self-reporting, as well as choosing not to admit opioid use. To take action and protect the public, the OCM found that promoting overdose prevention with “evidence-based interventions” also reduces stigma. The OCM stated that there are not yet any reliable methods of testing fentanyl on cannabis flower. While fentanyl test strips are used frequently to test if fentanyl is on other substances, they are only designed for substances that are water soluble. Most commonly, those strips are used with powders or pills to detect fentanyl. While it hasn’t been found in cannabis, it can be found in substances such as “heroin, cocaine, methamphetamine, MDMA, and pressed pills.” Described in a text block called “What We Know,” the OCM stated that to date, no one has died because of cannabis contaminated with fentanyl. “Warnings related to fentanyl ‘contamination’ in cannabis have increased as states continue to legalize cannabis,” the OCM wrote. “At this time, there have been zero verified incidents of fentanyl ‘contamination’ in cannabis. There is no guarantee that any unregulated cannabis product is free from contaminants or harmful ingredients.” The OCM warns that there are many unknowns about the possibility of fentanyl “contaminated” cannabis. “Cannabis products made available in the unregulated market may contain unknown or undisclosed contaminants and have inaccurate labeling. Reliable testing protocols for the presence of fentanyl on cannabis flower remain unknown,” the OCM wrote. However, the past has shown that cannabis has been found with unregulated substances in the past, such as K-2, otherwise known as spice, that is advertised as a cannabis product. The agency concludes the report by recommending buying legal cannabis products to ensure that your product is tested in a lab and does not contain any harmful contaminants. Rumors of fentanyl in cannabis have been perpetuated through law enforcement and also expanded into the arguments of legislators and political leaders. In December 2021, a Vermont-based police department told the media about an incident with a patient who consumed cannabis that tested positive for fentanyl, claiming that they revived the individual with CPR and multiple doses of Narcan. However, they later released a statement walking back the claims about a positive fentanyl test. “The seized marijuana in both incidents was submitted to a forensic laboratory where testing was conducted,” said the department. “[Brattleboro Police Department] was notified no fentanyl was found in the marijuana in either case.” High Times spoke with Peter Grinspoon, M.D., a medical cannabis specialist from Massachusetts General Hospital and also Harvard Medical School instructor, about the dangers of such claims. “It creates fear,” Dr. Grinspoon said in 2021. “Whenever there’s information about drugs—particularly cannabis—which is incredible, it makes it much harder for public health officials to get information that is credible out there. It’s like The Boy Who Cried Wolf—so it’s like the D.A.R.E. program. They said that cannabis does this, this, this and this, and teenagers didn’t believe it because it was against their lived experience. It sort of disqualified their other messages about drugs which are actually more dangerous—like heroin or alcohol. It just discredits the ‘official’ sources of information.”  However, that misinformation continues to be spread. In August 2023, Florida Gov. Ron DeSantis attended Never Back Down Super PAC in Iowa, where he stated that he would not legalize cannabis if he was elected president. “Yeah, I would not legalize,” said DeSantis. “I think what’s happened is this stuff is very potent now. I think it’s a real, real problem and I think it’s a lot different than stuff that people were using 30 or 40 years ago. And I think when kids get on that, I think it causes a lot of problems. And then, of course, you know, they can throw fentanyl in any of this stuff now.” In August, 517,500 fentanyl pills (about 115 pounds) disguised as “M30” oxycodone were seized by the San Bernardino Sheriff’s Office within the span of just one week. In 2021, San Bernardino County saw 354 people die because of fentanyl overdose. A report from the National Center for Health Statistics shows that in 2021, more than 106,000 people died of overdose deaths, and 70,601 of those people died because of overdoses related to synthetic opioids other than methadone (which includes fentanyl). The 32,537 remaining deaths were attributed to stimulants such as cocaine and psychostimulants with potential for abuse, such as methamphetamine.

https://hightimes.com/

Devendra Banhart Believes The Macarena Can Save Us All

Talking to Devendra Banhart is somewhat akin to listening to a Devendra Banhart album. You let go and simply go with the flow. At one point during our conversation, Banhart describes his love for sad songs and horror movies, comparing them to a ride. Having a conversation with Banhart is a similar experience. Discard the notes, forget any questions, and just enjoy as Banhart’s focus wanders while he discusses his latest album, Flying Wig, and the classic Los Del Río tune, the “Macarena.” Perhaps the 30th anniversary of the song was on Banhart’s mind? Whatever the case may be, Banhart had a lot of thoughts on the song from Antonio Romero Monge and Rafael Ruiz Perdigones. The song became a massive hit in 1996, getting the entire planet dancing with delight. Banhart believes the song can not only unite us once again but perhaps even make us some alien friends. On that note, Banhart’s soothing album is now out in the world, and he’s hitting the road for a tour. Most importantly, he’s thinking a lot about the “Macarena.” You like to start your day with music. What were you listening to this morning?  I was listening to one of my favorite songs of all time, called “Maki Madni” from Nusrat Fateh Ali Khan. I realized that I don’t know what the words are, so I’ve been trying to Google translate while I listen to this song. And then I listened to a little bit of Roger Eno. This is good, I’m giving a very thorough answer. And then my friend Bob was like, “You got to listen to this person.” I can’t think of their name now. How about you? What were you listening to? Honestly, the new Queens of the Stone Age album from the summer. I can’t let go of that one. I’ve heard that it’s quite good. The thing is, I will always have a sweet and soft spot for them. My hero is, one of my reasons I play music is this musician Caetano Veloso and he loves them. It just inadvertently, I’m always like, oh, they’re cool.  How was your experience translating lyrics? Did it change how you interpreted the song? They’re mostly bumming me out because it’s just so much better than anything I could ever write. I know that it’s a terrible translation. But one) oh my God, that translation is a thousand times better than anything I could ever write. And then two) because it’s a bad translation, I’m not getting the full color and the metaphor and the full image. So that’s depressing, only because I don’t know the language and I won’t probably ever learn that language. On my to-do list it goes, learn Sanskrit, learn Tibetan, learn Japanese, and I am never going to do it. Please, please fucking Tim Cook, make this shit happen. Put a chip in my brain.  At the same time, it’s funny that we’re talking about this magazine that I grew up not fetishizing, but almost being seduced by in this similar way that maybe as an adolescent you might see a porn mag. It was so beguiling and so enticing and exciting and it was a glimpse into a world that I had no access to. High Times is a lot like that, too. I was like, “Whoa, that’s interesting. This is cool. This is the coolest world and I have no access to that and I want to be a part of that world.” I always have this theory that with the right combination of plant medicine, you can access every language.  When did that theory start?  I’ve always had it. In fact, one of my best friends, Mel, was in Greece and she got super high on some Greek weed, I guess, or was probably something that she had in her suitcase. And then she’s like, “I knew Greek. I knew Greek. I was so high in this particular way, I knew Greek. I accessed the Rosetta Stone.” [laughs] I think that’s possible. I wouldn’t be surprised if, I’m sure Terence McKenna has a whole 5,000 hour talk about how it’s totally accessible through some plant medicine.  A good example is, you played with Carla Morrison at the Hollywood Bowl, and I don’t speak the language, but when I hear her singing it moves me. I don’t know if the lyrics are tragic or if they’re hopeful, though.  It would be amazing if the lyrics to “Macarena” were the most heartbreaking, gorgeous poetry imaginable. It’s, like, “Macarena” by [writer] Gabriel García Márquez. You never know. One of my favorite songs of all time is by Cesária Évora. It’s called “Petit Pays,” little country. It’s just a longing song, and I just know exactly what she’s singing about. I don’t know that language. I don’t speak Portuguese, but I can feel her speaking to me in a way that the only way I can equate it is dream logic. Listening to powerful music in the language you don’t understand is the equivalent to dream logic. Rarely, though, do I go and try to look up what the words are.  So, this morning I just had this feeling. I grew up listening to Ali Farka Touré as well. I don’t know actually what he’s saying. So, today I was going to go through this one record called Radio Mali that I really fucking wore out. I listened to the shit out of that record when I was a kid. My dad gave it to me. I sing it. I’m singing these words, I don’t have no clue what he’s saying. So we’ll see… What if it’s just, “someday a great politician named Trump will rise”? Who knows? What if turns out I love this pro-Trump sound [laughs].  [laughs] Man, worst case scenario thinking right there. But yeah, no, it’s a really fun extra kind of dimension to putting in a little bit of work into the music that you love. Just looking up who produced it, looking up who played on that instrument always leads to other records. Oh, that guitar player that played on that record made a solo record. Let’s check that out. And this is the same thing with lyrics. I love the songs in a different language, but let’s look up what the lyrics are. “Oh, okay, based on a poem by blah blah, blah. Let’s get that person’s book.” It’s a very fun archeological dig.  So, you got bummed looking at these lovely lyrics on Google translate. As a successful songwriter, does that feeling never stop, like, oh, I’ll never be that good as this song? That’s never gone away for a second. But the paradox is that within the thought, “Wow, I’ll never write anything as good as this,” there’s also, “Wow, I’m such a good writer.” There are two insane extremes. Rarely am I like, “Well, I’m an okay writer. I’ve dedicated my life to it. I know how much I work on it, and it’s okay. The world will keep going when I’m gone. It’s not a big deal, but it’s not the worst, either.” Now, that’s how it should be.  But the reality is mostly, “I’m the greatest writer that’s ever lived of all time, and I’m the biggest piece of shit and everything should be burnt. What am I doing?!” It’s really there where it mostly is. It should be just, “Okay, I do my work.” It’s such a funny thing, such a bummer. It’s a sweet bummer because Google Translate is doing something without trying that I spend 12 hours trying to do while writing, which is: counterpoint.  Counterpoint is what makes poetry interesting, what makes writing a song with a theme that is so fucking banal, possibly interesting. You’ve heard what this song is about a million times. So, how can this be interesting is counterpoint, the poetry of it, and the symbolism. Trying to be a non-subjective human being is impossible with your own work. You’re trying to do that, trying to even trip yourself up and create a little hiccup in your own narrative, in your own linear, let’s say, pathway.  You’re trying to chop down some new pathway in this jungle, but Google Translate just happens to do it so perfectly. “Fuck! Why couldn’t I think of that? That’s exactly what I wanted to do.” There’s a lot of that. I’m trying to psych myself out.  For the new album, what were some new paths you wanted to journey down? Well, it was a collaborative thing. I wasn’t alone, just me and my machete trying to hack my way through the brambles and tangles and vines. I was there with Cate. So, [producer] Cate Le Bon was such a wonderful fucking partner. It was supposed to be co-produced, but five minutes into tracking, I just said, “Cate, you’re producing. I trust you so much.” Trust is so, like, oh my goodness. It’s a real waterfall of nectar to discover trust. That’s why it’s so painful when trust is betrayed, because it’s so extraordinary when you find it, when you feel it. I mean, “I trust you” should be more powerful than “I love you,” you know what I mean? I love burritos, but I don’t trust burritos. Now, “I trust you,” it’s like, whoa.  I think we were surprised that we were in this natural, beautiful country, classic California environment, even with a bit of that California history in it. It was the house where Neil Young had written “After the Gold Rush,” and we’re feeling that. There’s just gorgeous trees everywhere and hawks flying around and we’re in that pastoral California feeling. I’m listening to the Grateful Dead or ambient music pretty much nonstop. Amidst this totally pastoral environment, we make this record that to me and to Cate, I guess, sounds like the desolate and more dystopian side of Japanese City pop. We’re trying to create something that feels like if you were watching Blade Runner and the camera just moves away from Harrison Ford and focuses on an extra, and then the extra goes to their therapist. “Yeah, today it was blah, blah, blah,” and then they went shopping. We have the soundtrack for this extra in Blade Runner. So, that to me was surprising because we were in the complete opposite of that environment.  [Laughs] Also, it’s funny, I wrote in my notes that the album feels like – and I know it’s a cliche – just a cool breeze. Wow, that’s amazing. That makes me so happy. Because it’s a beautiful thing to share and have somebody feel what you’re doing. We didn’t see any of that. We were feeling the cool breeze while we were recording, but we were like, Oh my God, this is so funny. It’s the opposite of a cool breeze. This is a hot fart, synthetic hot fart.” [laughs]  [Laughs] Well, it’s like that thing you’re saying with, “Hey, what if you translated the ‘Macarena’ song”? Maybe the content and the execution are just the complete opposite. Ya’ never know what the true feeling is sometimes.  I actually just looked up “Macarena” lyrics. The first line is, “I am not trying to seduce you. When I dance, they call me Macarena and the boys, they say that I’m good. They all want me. They can’t have me come and dance beside me. They move with me, they chant with me. And if you’re good, I’ll take you home with me.” Okay. I mean, yeah, it’s a seduction dance. I was hoping for something a little bit more… What a bummer.  That was actually very nice to hear [laughs]. My favorite song off the album is “Twin.” Like for that song, when do you know in your gut, you really want to sit with a song and let it breathe as much as that one does? I guess that’s getting into the realm of process and intuition. I overdo it. I am a real quantity over quality person. I’ll do 100 drawings, so I get the two that I can show that are okay. And so, you arrive at that place of here’s the appropriate length with overdoing it and then underdoing it; it’s the only way I can figure it out.  I never know immediately. It’s never clear. I never have any idea. And then also, I think Cate is much more of an interesting person all around, a much more artistic person all around and a much better player and singer. It doesn’t hurt. I mean, if you’re going to make a record with someone, try to get somebody that’s much better at everything than you, it helps. She would push it.  My favorite type of poetry is haiku and my favorite book has, like, one word in it. I like to bring it back in as short as possible, while Cate would much prefer to pace it out, give it time. So, that was part of our dynamic. A lot of the meeting in the middle was the length of these songs. For “Twin,” Cate’s version could have been 20 minutes and I would’ve preferred a 45 second version of that.  I want to give you a festival. I want to have a festival, and all the 100 bands play half a song. That’s a good festival. I mean, I would be into that festival.  Have you pitched that idea to anyone? Kind of a speed freak festival. We’d have the highest organic Ritalin for sale, I’m sure, but it’d be like, “Here’s the hook of my tune and the next band. Okay, thank you. Next band. Wow.“ Do you think people would be satisfied?  What are these three-hour sets? Who the fuck wants a three-hour set? That blows my mind. It hurts to sit for that long and it hurts to stand for that long. I mean, okay, if we have Casper, the Casper Festival, everybody gets a bed and a toilet. Okay, we’ll do a three hour set.  Valid points, I say. That’d be a nice festival, right? Everyone gets a lazy boy and a toilet. Fuck that would be awesome.  So, when you’re on tour— Okay, let’s get it together. Yeah, let’s do it [laughs].  [Laughs] I’ll make some calls. You’re about to go on tour. What do you expect or hope for playing these new songs live? Well, we haven’t presented them the way that we are about to begin presenting them. I’m actually quite jetlagged. I got back from India yesterday. Now, this work begins by trying to really work out how to present these tunes. Some of these songs are going to stick, some won’t. We’ll be so excited to present them as close to whatever, as close to the record I guess, as possible. But so far, I’ve only really noticed something with my favorite song on the record. The one that means the most is a song called “Charger.” The first line is so dumb: “It looks like I lost my charger.” Even though subconsciously the reality of losing my charger for me, at least, is real anxiety. Genuine anxiety and kind of panic and terror. It means losing my charger is actually quite awful, but it’s such a silly thing to sing.  I’ve only played it a handful of times, but people laugh at the first line, like, people crack up. The song is actually quite serious. And so towards the end, the mood changes so much and the feeling in the room changes so much. So, that’s so fun to experience. I’m the butt of the joke at the start of that song. And towards the end, we’re all in a very different zone.  That’s a nice arc. It’s like when you laugh at a character in a movie, and then by the end, you feel terrible for having laughed at them. That’s right. I just love making people feel bad. This is the main thing that I’m into. It’s the only thing that gets me going [laughs].  [laughs] I don’t think your music makes people feel bad.  Everything makes me feel bad.  I’m sorry.  I love it, though. You see? It’s funny. Making a song, I mean, I love a sad song. My favorite song is the sad song. It’s going on a roller coaster ride. I like a sad song. I like a horror film. If it’s done right, it just takes me away. It’s a ride. And crying feels good. It’s embarrassing and humiliating, obviously, when you’re not trying to cry.  I mean, I cry, just coming up with a lyric. It’ll always emerge at the worst time. And I don’t have a pen or a paper or something to record it. It’s just like, whoa. That’s where it comes up, where it emerges.  And then the same thing with weeping, it’s never here alone in the house. It’s like at the post office or ordering a cup of coffee. Suddenly something just hits me, maybe the way somebody speaks to someone or the way somebody is opening the door for someone. Just a moment of real kindness, and I fucking lose it. I lose it. It’s such a cleansing, beautiful feeling.  So, this thing of, is that a sad song? Is that a happy song? Yeah, I don’t understand. I mean, “Macarena,” I really want to do a cover of “Macarena” that’ll make people cry [laughs]. I’m excited to give that a shot. A really dark, sad, sad version. Oh, yeah, that’s exciting. I’m getting Nick Cave to do “Macarena.” You should work on this today.  You got it. The lyrics are right here in front of me. Yeah, because there’s something here… “But don’t you worry about my boyfriend. He’s a boy whose name is Vitorino. I don’t want him. Couldn’t stand him. He was no good.” I mean, that’s already like, whoa, heartbreaking.  Do you ever cry at concerts? I think one of the most special parts of writing and recording and then presenting music is there are not that many places where we are collectively weeping. There’s funerals and, of course, that’s the ultimate in a way, that’s the main place where we’re collectively weeping. Maybe the theater, except that we’re not really seeing each other in the dark. It’s at a show where that real collective weeping is happening in a very particular way. It doesn’t happen too often. It really builds, even on a subconscious level, a feeling of community, which we really all long for, especially in the West. We don’t live this life. We don’t go to school, and they’re like, well, today we’re going to learn a bunch of things, but the most important one is ritual, healing, and community.” You’re never going to hear that ever. But those are the three things that we really need in our lives. We really long for these things, subconsciously and unconsciously.  Going to a concert has all three elements. There’s a ritual. It is absurd. A concert, you don’t need a concert, nobody needs a concert, that’s such an absurd thing [laughs]. But, of course, it’s so important. In the eyes of a kind of very materialistic and western logical scientific world, a concert is the most absurd thing ever. But you could look at all art that way, of course, as well as religion and spirituality. Of course, these are also the most important things.  So, there’s a ritual there [at concerts]. It’s a community. You’re around people. You don’t have to talk to any of these people, but just being around them and sharing that collective experience that is so even subconsciously meaningful and precious. And then healing. I mean, that’s the main thing. Born to heal. I was born just fucking straight out of the womb wishing to heal.  I saw Shannon Lay playing a set her acoustic guitar and singing, and then she sang an acapella song, fucking acapella, and everyone lost it. You can have a million bells and whistles, and that really can hit hard, too, or you can just go do something as simple as acapella, as pure as acapella. It could also be the most mortifying, embarrassing thing on the planet. I mean, really, it could be the most like, “Oh my God, please can this end?” But when it’s done right, it’s so beautiful. So beautiful.  Yeah, I agree.  I’m not sure what the point was, but back to the “Macarena.” [laughs] We’ll circle back to “Macarena,” but I have to ask you about India. How was your experience? Were you there for work? In a sense, I was there for work. I’m actually meaning to explain that to all the people I work with, because I went there to meet up with my teacher, who’s in Himachal Pradesh in the north of India, very near Dharamsala. I went just to be at the monastery. My teacher has a monastery there. When I say it’s for work, it’s because I’m about to start this tour, so I needed to go there and get a few things cleared up, do a little bit of that purification work, and a little bit of work to just be even more present. It’s for the benefit of work. Yeah, I was just in India with my teacher doing some stuff [laughs]. And did it work? Feel more present?  Well, I did there, I did there. But the second I got back I was like, “Blah, back to it.”  But you could circle back to that feeling.  Yeah, sure. I could give it a shot. I can give it a shot.  Good luck. Any closing statement on “Macarena”? Well, I’m scared of global warming. It pretty fucking hot right now. I think we fucked up the planet to a possibly totally reversible place. All that is to say the only solution is the “Macarena.” I think the “Macarena” is the only solution. We need to broadcast the “Macarena” on our biggest satellites out into space. It’s the only thing the aliens are going to listen to. Fuck the Voyager. You know what I mean? Putting Blind Willie Johnson on there? Give me a break. I’m talking about the “Macarena.” That’s the only thing that the aliens will go, “Oh wow, this is an advanced society and we need to preserve these people.” [Laughs] Thank you for the time, Devendra. Wish I’d known that we were going to talk about “Macarena” the whole time. This is, like, a dream for me, know what I mean? I’m talking to High Times about the fucking “Macarena”! I feel I’ve had a… high time? Hey, ha-ha! Alright, I’ll talk to you later, man. 

https://hightimes.com/

Research On Cannabis, Yoga Suggests That Setting Influences Mental Health Benefits

In a recent study from the University of British Columbia, researchers have unveiled new insights into the relationship between cannabis consumption and yoga. The study indicates that individuals who practice yoga after using cannabis may experience enhanced mindfulness and a heightened sense of mysticality. The research, which originated as a psychology dissertation, examined “the impact of contextual factors during cannabis use on well-being outcomes.” The paper’s author, Sarah Elizabeth Ann Daniels, highlights a significant disparity: While research into psychedelic therapy often emphasizes the importance of setting and intention, this emphasis is notably less prevalent in studies related to cannabis. While cannabis connoisseurs understand that the plant, like shrooms, is indeed psychedelic, the stoner community doesn’t always place the same weight on integrating set and setting into cannabis use. Yoga, which often utilizes intention-setting, could offer one modality to change that.  “When researchers explore the use of other psychoactive drugs for mental health treatment, there’s a strong focus on factors outside the direct effects of the drug, like mindset, environment, and behavior,” Daniels says. “This is because evidence suggests that these elements can dramatically influence therapeutic outcomes.”  The study underscores the importance of the context in which people enjoy cannabis. Its conclusions suggest that the environment and activities, aka the set and setting, invoked while under the influence of cannabis may play a pivotal role in shaping the user’s experience. Drawing a parallel with the world of psychedelics, the research supports the psychedelic-approved conviction that the setting and mindset during cannabis consumption can significantly affect its therapeutic benefits. While the cannabis community is often discussed in terms of a potential model for psychedelics to follow, as weed first gained mainstream societal approval, perhaps it’s time to reverse this relationship and see what marijuana can learn from psilocybin, ketamine, and other substances which therapeutically endorse set and setting.  To investigate the role of context within a cannabis experience, a weed trip, if you will, Daniels orchestrated the experiment involving 47 participants. She instructed them to self-administer cannabis on two occasions, spaced one week apart. In one session, participants engaged in yoga, while in the subsequent session, they just did whatever they usually enjoyed doing while high. The most common activities cited included eating, viewing TV or films, performing household tasks, socializing, and other hobbies. The research evaluated participants based on several criteria, such as “state mindfulness,” “mysticality of experience,” and “state affect.” Regarding “state mindfulness,” Daniels sought to gauge levels rooted in “both traditional Buddhist and contemporary psychology models of mindfulnesses.” This measure illuminated participants’ awareness of their mental states and bodily sensations. On the other hand, the “mystical experience” metric looked at more profound moments – such as experiencing deep peace and tranquility and perceiving a distorted sense of time, a common occurrence for cannabis trips.  In her research, Daniels identified a marked enhancement in participants’ reported mindfulness when they combined cannabis use with yoga practice. Additionally, their “mysticality of experience” saw a notable uptick. Despite mysticality traditionally being more aligned with psychedelic substances, Daniels points out, “While cannabis is not considered a traditional psychedelic,” it has been observed that “recent evidence indicates that it shares many commonalities with psychedelic-induced altered states.” When it comes to “state affect,” which essentially gauges an individual’s emotional and mood state, Daniels found no significant variance between sessions with yoga and those without. Pairing cannabis and yoga is nothing new. Ancient yogis in India touted the benefits of hashish, and classes such as the LA-based Ganja Yoga invite people to partake to enhance their yoga experience.  Of those participating in the study, six were newcomers to yoga. Thirty individuals claimed to engage in yoga sporadically or occasionally, with the remaining 11 being regular or frequent practitioners. 72% of the participants, or 34 individuals, expressed interest in blending cannabis and yoga in the future. In a symbiotic relationship, yoga not only amplified their cannabis experience, but the inclusion of cannabis also heightened their appreciation for yoga. Daniels notes: “The most frequently reported theme was enhanced physical awareness, where 15 participants articulated a heightened cognizance of their body, its movements, and sensory experiences. Many described feeling more ‘in touch’ or ‘in tune’ with their bodily sensations and expressed that their awareness of movement and physical sensations was at a ‘deeper’ level than usual. Importantly, they emphasized that this was distinct from their regular (non-cannabis influenced) yoga or physical activity sessions.” Reflecting on her findings, Daniels suggests, “These results underscore the importance of considering context and offering guidance to those using cannabis for therapeutic purposes, with the aim of enhancing its positive impacts on mental health and well-being.” The primary takeaway from the study is that going forward when prescribing cannabis (although you don’t need a doctor to implement this information), physicians should consider set and setting as part of cannabis consumption.  “Physicians have long identified a lack of clarity on the optimal approach to prescribe cannabis for therapeutic use,” the study reads. “Offering precise behavioral guidance and educating about the influence of environment and mindset can potentially optimize the benefits and reduce the downsides of therapeutic cannabis use. Given the favorable response to the yoga component, recommending yoga or similar mindful exercises might be highly beneficial.”

https://hightimes.com/

Eureka, CA Decriminalizes Psychedelic Plant Medicines

Eureka, CA, has passed a resolution decriminalizing entheogens and psychedelic plant medicines, making it the sixth California city to do so and the second such city in Humboldt County. The Eureka City Council unanimously approved an initiative last week to decriminalize plant medicines such as psilocybin mushrooms within city limits. The announcement came less than two weeks after CA Gov. Gavin Newsom vetoed an initiative which would have decriminalized psychedelics statewide. The City of Arcata, just a few miles to the north, voted to decriminalize in 2021 thanks to efforts by a group who also provided the language used in the Eureka resolution, Decriminalize Nature Humboldt. According to an article in the Lost Coast Outpost, the resolution was passed without much trouble from the council, though a particular phrase was removed from the language of the bill. The council voted to remove language which seemed to endorse entheogenic plants’ ability to “catalyze profound experiences of personal and spiritual growth.” Not for nothing, but one of recently deceased Johns Hopkins professor Roland Griffiths’ first studies on psilocybin in 2006 was on psilocybin’s ability to induce mystical and spiritual experiences in the user. Much of Griffiths’ later work at Johns Hopkins has been referenced in similar legislative discussions surrounding the legality of psychedelics. Other than the removal of the aforementioned phrase, the resolution was passed without much protest from the rest of the council members.There were some concerns voiced by local law enforcement representatives, mirroring Gov. Newsom’s concerns about potentially unforeseen consequences to the resolution. City Manager Miles Slattery, however, pointed out that he had consulted with the Arcata Police Department who reported no serious issues to him after just over two years of psychedelic decriminalization. He also pointed out that the City of Eureka only saw five cases of arrests related to entheogens in the previous year and almost every case was related to something more serious such as domestic violence.  Councilmember Scott Bauer also voiced concerns over friends who had succumbed to bad bouts with Lysergic Acid Diethylamide, commonly known as LSD or acid. Councilmember Bauer said many of these friends were “gone” from these trips while also expressing concern over the purported possibility of such substances to inhibit child brain development, though he ultimately voted to pass the measure. Hundreds of letters from concerned citizens were reportedly submitted to the council for consideration and dozens of members of the community showed up in person at the council meeting to speak about their personal experiences with psychedelics. They attested to ways in which they could foresee entheogenic plant medicines bringing net positives to both their own personal lives and to the collective good of a county awash with an inordinate amount of mental health and substance abuse disorders. “What we genuinely need as human beings in this chaotic world is a helping hand, and psychedelics — from a nurse perspective, from a humanistic perspective, from my own perspective — psychedelics lend a hand that can hold you and guide you into a good direction, as long as you have the foundation built,” said Randee Litten, a nurse in the City of Eureka who co-founded a local ketamine treatment center. “I know that’s the concern, but I can tell you that we’ve been doing it for a year and a half, and I can’t even tell you how many community members we have helped. And it’s the reason that I’m still here, because I love this community and I have never in my entire career felt like I am doing so much good for this community until we discovered how well psychedelics can help human beings. … I finally feel alive again, like we’re doing something good for our community.” Councilmember G. Mario Fernandez offered words of reassurance that the measures taken by the City of Eureka would, unequivocally not be reflective of Timothy Leary-esque sentiments from the chaotic psychedelic boom of the 1960’s. “This isn’t a call to ‘turn on, tune in and drop out,’” Fernandez said. “Instead it would be to allow for folks who do take these substances for healing to reach out to medical and mental health professionals — or law enforcement, if things go towards a more negative experience — without any fear of reprisal.” A local teacher, Rachel Riggs, told the council that she believes psychedelics can provide unparalleled healing in a community with an elevated rate of adverse childhood experiences. “Entheogens are anti-addictive [and are] among the safest substances being studied in the treatment of addiction and mental health problems,” Riggs said. “There are very few side effects, especially when under the guidance of a therapist or with proper education.”

https://hightimes.com/

New Research Exploring Psychedelics as a Treatment for Anxiety in Cancer Patients

The use of psychedelics as a treatment for serious mental health conditions continues to gain traction as multiple studies focus on the psychological symptoms commonly experienced by cancer patients. In one study, researchers at the University of Washington are exploring the use of psilocybin, one of the psychoactive components of magic mushrooms, to treat anxiety experienced by patients with metastatic cancers. Other research focuses on using psychedelic therapy to help patients receiving hospice care cope with demoralization.  In a separate study at the Center for Psychedelic Medicine at the New York University (NYU) School of Medicine, researchers are conducting a clinical trial using psilocybin-assisted therapy to treat existential distress in patients with advanced-stage cancer in collaboration with colleagues at the University of Colorado. Dr. Xiaojue Hu, a psychiatrist and researcher at NYU’s Center for Psychedelic Medicine, noted that the study “is building on the same work in this area originally done at NYU in the 2010s.”  “Now, there are many other studies using psilocybin in cancer patients, including a study using psilocybin in combination with multidisciplinary palliative care to treat demoralized cancer survivors with chronic pain going on at Emory University,” she told SurvivorNet. Hu explained that psychedelic-assisted therapy could be a more sustainable and effective treatment for cancer patients than other commonly prescribed alternatives including antidepressants.  “From the psilocybin research on depression alone, we’ve seen clinically significant impact from just one or two doses of psilocybin in conjunction with therapeutic support that can last up to 14 months for some patients,” said Hu. “This is in contrast to antidepressants, which people have to take on a daily basis for potentially years, with a risk of relapse when the meds are tapered off.” Clinical research and other studies into psychedelics such as psilocybin and MDMA have shown that the drugs have potential therapeutic benefits, particularly for serious mental health conditions such as depression, PTSD, substance misuse disorders and anxiety. In January, a California biopharmaceutical company announced positive results from a clinical trial testing MDMA as a treatment for PTSD. Research published in the peer-reviewed journal JAMA Psychiatry in 2020 found that psilocybin-assisted psychotherapy was an effective and quick-acting treatment for a group of 24 participants with major depressive disorder. A separate study published in 2016 determined that psilocybin treatment produced substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer. Although the research is promising, Hu said that psychedelic-assisted therapy does not work for everyone and that further research is needed to confirm the efficacy and safety of the treatment. “Psychedelics aren’t a panacea or miracle cure for anxiety and depression, as there’s still much that’s unknown about them and there’s always the potential for adverse effects, like with any treatment,” Dr. Hu said. Hu added that research has focused on using psychedelic treatments in conjunction with multiple sessions that integrate more traditional forms of therapy. “Most of the research is also done when psychedelics, such as psilocybin, are used in the context of therapeutic support with usually two therapists, which can include up to three sessions of preparation and three sessions of integration afterwards,” she said. “So the results are not completely due to the physiologic effects of psilocybin alone, in my opinion, but must be taken into context with the therapeutic and environmental support that’s also offered.” Hu also noted that psychedelic-assisted therapy is conducted in a tightly controlled environment because the set and setting in which a patient receives the treatment can have an impact on its success. “We typically don’t expect different results if someone took their Lexapro [an antidepressant] in different moods, with different people, or in different environments, but we definitely can when it involves psychedelics,” she said. While the research continues, the use of psychedelics to treat serious mental health conditions such as anxiety and depression has yet to achieve approval from health regulators. The U.S. Department of Health and Human Services projects that the Food and Drug Administration will eventually approve MDMA and psilocybin mental health treatments, according to a letter from the department in May 2022. In 2017, the FDA granted MDMA-assisted therapy Breakthrough Therapy designation, indicating that the therapy is a significant improvement over existing treatments.  The Multidisciplinary Association for Psychedelic Studies (MAPS) predicts that an application to use MDMA to treat PTSD will be submitted to the FDA at some point in 2023, and approval could come as early as 2024. But so far, MDMA-assisted therapy has not been approved by any regulatory agency and the safety and efficacy of MDMA-assisted therapy for the treatment of PTSD have not been firmly established. “MDMA and psilocybin have the most clinical research and legal momentum behind them right now, with psilocybin already being legalized in Oregon and Colorado and MDMA phase III trials recently being completed,” said Hu.

https://hightimes.com/

Cannabeginners: Delta-8, Delta-9, Is All THC Created Equal?

Delta-8-Tetrahydrocannabinol (delta-8, also seen as ∆8-THC) is a psychoactive and intoxicating cannabinoid similar to Delta-9-Tetrahydrocannabinol (the commonly found THC we all know well). Delta-8 has seen a surge in popularity due to a legal loophole in federal regulations that limits THC to 0.3% in hemp products but has no limit for delta-8. Roger Adams and a team of researchers at the University of Illinois were the first to report partial synthesis of delta-8 in 1941. It wasn’t until 1966, when Dr. Raphael Mechoulam and his colleague Dr. Yechiel Gaoni, achieved a total synthesis of delta-8 as part of their groundbreaking work at Hebrew University. In 2002, Dr. Mechoulam applied for a patent on the conversion of CBD into delta-8 and THC through various methods, which he received in 2008, and expired in 2022. As delta-8 is an isomer of THC, they have a similar chemical structure, and the only difference is the location of a double bond between two carbons. They are both psychoactive chemicals with intoxicating, euphoric properties.  A year before Dr. Mechoulam’s patent expired was the first time the American Association of Poison Control Centers “introduced a product code specific to delta-8 THC into its National Poison Data System, allowing for the monitoring of delta-8 THC adverse events.” That would mean that, officially, 2020 was the year that the delta-8 craze began in America.  The answer to this question is complicated and depends on how you define a synthetic cannabinoid. The National Institute on Drug Abuse says that “Synthetic cannabinoids are human-made mind-altering chemicals … they are similar to chemicals found in the marijuana plant.” In order to be synthetic, a cannabinoid must be made by humans and be similar to chemicals found in the plant. In the case of delta-8, it is not similar to a cannabinoid found in the plant, it naturally is found there in very small amounts. Even though the majority of delta-8 on the market is from a lab, not the plant, the cannabinoids were still made by the plant, they were converted by humans.  The FDA’s guidance is a little more complicated. While they note delta-8 is “produced naturally by the cannabis plant,” they are clear that “concentrated amounts of delta-8 THC are typically manufactured from hemp-derived cannabidiol (CBD).” As the word “manufactured” is another way of saying something was “made,” it is ambiguous on if the FDA would view delta-8 as synthetic, and it would likely depend on where it was sourced from (a plant versus a lab).  As there are only trace amounts of delta-8 found in hemp and cannabis plants, an incalculably high percentage of delta-8 on the market was produced in a lab using the chemical conversion that Dr. Mechoulam discovered.  The publication Chemical and Engineering News (CEN) described the process as “refluxing CBD in an organic solvent, such as toluene or heptane, with p-toluenesulfonic acid or another acid that serves as a catalyst.” In a controlled, regulated environment, these reactions would be done by PhD chemists to ensure there are no harmful by-products left in products sold to consumers, but the hemp industry is notoriously under-regulated with no requirements for lab testing. Experts who spoke to CEN described the conversion process as “pretty aggressive” and noted that it used “strong acids,” and in order to neutralize those conditions they would need to use strong bases, metal catalysts, or a number of other methods. While it is possible to purify converted delta-8 from unwanted contaminants, reaction leftovers, or other by-products, most people doing those conversions are not chemists and do not properly distill it or use appropriate testing methods.  A literature review published last year found that, “No comprehensive review articles have been published that focus exclusively on Δ8-THC,” meaning their study was the first to focus on delta-8. Rather than finding delta-8 to be more harmful than THC, they found “that Δ8-THC has [a] weaker potency than Δ9-THC.” Jeffrey Raber, is a cofounder and the CEO of the Werc Shop, a California-based cannabis contract manufacturing and testing firm, who saw the potential of delta-8 several years ago. “It’s a very interesting molecule, one that has very different physiological activity depending upon the entourage,” said Raber, who is urging regulators to address the testing and purity concerns around delta-8 while still allowing safe use. The FDA received 104 reports of adverse events in people who used delta-8 products between December 1, 2020, and February 28, 2022. None of those were fatal, and the events included “hallucinations, vomiting, tremor, anxiety, dizziness, confusion, and loss of consciousness.” Poison control centers around the US received 2,362 cases of delta-8 exposure from January 1, 2021 (when delta-8 was first coded) and February 28, 2022, with one pediatric case that resulted in death.  What is not clear is if those negative experiences and that one death were caused by delta-8 itself, or the rampant impurities in delta-8 products. Due to the lack of regulations, much of the delta-8 on the market is tainted with trace amounts of other cannabinoids (possibly THC or even Delta-10-THC, another isomer) and by-products from the chemical conversion.  Kyle Boyar is a research associate at the Center for Medicinal Cannabis Research, and has reported that olivetol, a chemical precursor to THC, is a common by-product found in delta-8 products, adding “I don’t think anybody really knows the safe inhalation dose of olivetol.” As there are a range of solvents used for the conversion from CBD, there can be a wide variety of residual solvents in delta-8 products, and some, like dichloromethane and trichloroacetic acid, don’t even have standardized testing methods developed.  While 2020 was the year of the craze, what was the “why” behind the delta-8 craze? Some sources note that the delta-8 craze began only after the price of CBD plummeted, and hemp companies needed a new way to turn a profit. So was a need to stay profitable the reason behind the delta-8 craze? It certainly was a contributing factor, but the real cause of the delta-8 craze, like the CBD craze before it, was cannabis prohibition. If there was no cannabis prohibition, then everyone using less safe hemp products could use legal, lab tested cannabis products. As long as whole plant cannabis containing over a certain amount of THC is illegal, people around the world will look for ways to get around that limit and create legal loopholes, and that is all delta-8 is, a new loophole to circumvent prohibition. 

https://hightimes.com/

Throwing Shade

Christy Ai was trained from birth to move gracefully between two distinctly different worlds. Part of her life was lived in the Chinese language, among family in Asia, embracing the traditions of generations. The other part was rooted firmly in the U.S., where her parents moved to finish their studies as college post-graduates and where she was born, naturally conversant in English. Ai moved through the world as an American when in the States, as a Chinese when in China—and, it turns out, as a rebel throughout it all. A “good” girl careful to fulfill her responsibilities, Ai does things her own way—with a bit of punky mischief. She made her family in China happy by being accepted to Cornell University and taking a degree in hospitality, but her rebellious side drew her academic focus to casinos and gambling. She went into banking as a financial executive with J.P. Morgan but ended up working with alternative finance. She launched a highly lucrative business but centered it in cannabis.  Ai, 32, was accused by her family of being a drug dealer and bore the accusation with grace. She’s confident she’s not breaking any laws by growing cannabis and selling it according to California’s dictum. Plus, her grandmother has been enjoying the effects of the CBD/THC-infused balms and edibles Ai has been supplying her with since 2017. A relative with autism also appreciates how the plant products Ai gives him can calm his anxiety. Meanwhile, China itself has changed its stance slightly, beginning to experiment with hemp production and CBD development in a big way. Things generally come around to Christy Ai’s way of doing things—and when they don’t, she charts her own course. Having watched her best friend’s family suffer bankruptcy as the result of the 2008 financial crisis, Ai became interested in crypto in early 2011. Things were bad enough in the States that year, but they were even worse in China, which Ai says already constrains citizens’ access to their own money; ordinary cash transfers between Hong Kong, say, and Macao can be difficult if not impossible to complete. The idea that money you yourself worked hard to earn and save can be kept from you by the government was bewildering to Ai.  When cryptocurrency came to prominence, Ai could immediately see that it was a way to access the money you earned and grew and saved without anyone telling you if you could or not. Crypto was a way to be free.  Intrigued, Ai was an early adopter of the currency while still at J.P. Morgan. When cannabis became legal in California, she was interested in learning more and was soon active in the Discord crypto community that surrounds cannabis. Eventually she purchased a KODA NFT from the same group who created the Bored Apes Yacht Club collection. Her NFT, Koda #13528—a cuddly nine-eyed bear-like creature with fringed ears and an adorably chubby build—is one of only 10,000 “rare alien”creatures released to tease the launch of a new virtual community.  But back in 2020 when she and her partners were attempting to bootstrap the lease of an 1880s building in downtown Los Angeles, a 100,000-square-foot former adult diaper factory that they intended to revamp into a state-of-the-art cannabis grow facility, Ai hadn’t yet connected all the dots that would become the road map to her future. “We had our operating license in place and all of the other missing pieces, but the one thing that was an issue was funding,” she says, still sounding frustrated. “And it wasn’t just funding in terms of the money needed to build an entire cultivation, but it was also: how will people pay you? How do you pay rent? Landlords don’t take bags of cash. Utility companies don’t take bags of cash. I realized cannabis was really the true, modern day, unbanked industry for a First World country. I thought about it until the answer occurred to me: The answer was crypto.” Harnessing the power of crypto allowed Ai and her partners to procure and establish a robust $10 million grow facility known as Vangarde Cultivation in that old building in DTLA. Today they operate under a social equity license to provide some 30 employees with full time employment. Operations are focused on small-batch craft cannabis that is hand-raised, hand-harvested, and stick-trimmed by hand. Each of the nine grow rooms is personally overseen by a specific individual who is charged with the success of the flower inside. For her part, Ai sees herself as being personally charged with the success of each specific human individual inside the building. She and her business partner provide services like apprenticeships and training, housing and even cars to employees who may have sacrificed due to their involvement in the cannabis industry. “We give a lot back to our employees in terms of literally helping to get new apartments and cars because you don’t have a credit score when you work in the cannabis industry,” Ai says. Not content with merely co-owning Vangarde, one of the largest indoor growing facilities in Los Angeles, Ai struck out on her own to found The Otherside flower brand (as in: The grass is always greener on . . .) in 2022. Her KODA NFT proudly acts as the brand’s mascot and its silent voice. The Otherside’s small-batch craft cannabis is currently found in 13 California dispensaries—and counting. The brand’s three proprietary strains include perennial best-seller Sugarberry Cream, a trichrome-rich flower that bursts with lemon meringue and cherry-touched cotton candy flavors, as well as Bittersweet Jealousy, and Sunrise Papaya.  Ai’s KODA NFT is adapted to be slightly different for each strain it represents. But here’s the secret: If you look closely, you’ll see that the KODA is making a different American Sign Language (ASL) sign for each strain.  Ai explains: “Our spirit is reflected through the infamous KODA NFT that pays homage to the war against cannabis prohibition and celebrates the power of cryptocurrency. This KODA is our secret little ‘eff you’ message to everyone who tries to keep the industry down and to all the discrimination we still face as an industry today.” Here’s the code: According to Ai, who is always up for a bit of disruption and is known for swimming against the stream, this is a clever way of throwing shade while nodding to the ASL community and indulging in a bit of mystery. “I thought of it as a code, as a secret message,” Ai says. “We wanted to incorporate if-you-know-you-know messaging. That’s why it’s silent, like ‘They’ve been judging us the entire time and now we’re just silently judging them back.” Find The Otherside online at otherside-la.com

https://hightimes.com/

Elon Musk Offers $1 Billion to Wikipedia to Change Its Name to ‘Dickipedia’

Billionaire Elon Musk floated spending $1 billion on a joke—specifically to rename Wikipedia as “Dickipedia,” while right-wing distrust in the open-source database grows.  Musk broke the internet last year when he bought Twitter for $44 billion dollars and whittled it down to the bones, transforming it into a monetizing mill that charges for blue check marks, subscriptions to verified accounts, and the platform might charge all users $1 per month. Now Twitter/X is only worth one-tenth the amount it was worth when Musk bought it. Fortune reported last September that Twitter/X has lost 90% of its value and could be worth just $4 billion.   He’s at it again, now with Wikipedia. On Oct. 22, billionaire Musk posted a screenshot on X, formerly Twitter, showing that “Wikipedia is not for sale.” He then offered the database $1 billion if they change the Wikipedia name to Dickipedia, even if they quickly change it back. “Have you ever wondered why the Wikimedia Foundation wants so much money? It certainly isn’t needed to operate Wikipedia,” Musk posited. “You can literally fit a copy of the entire text on your phone! So, what’s the money for? Inquiring minds want to know.”  X users used the “Add Context” feature on the app to answer his question. “Expenses: $146m – 43-45% engineering improvements, product development, design and research, and legal support – 31-32% grants, projects, trainings, tools for contributor capacity, and support for the legal defense of editors – 13% Administration – 11-12% Fundraising,” users wrote. The next day, Musk posted on X that he’s offering $1 billion to the platform if they change its name to “Dickipedia.” “I will give them a billion dollars if they change their name to Dickipedia,” he posted, adding that they could change the name back. He replied to his post, adding “In the interests of accuracy.” Wikipedia is the world’s largest database, and is using the first Google result to pop up when users ask the internet any question. Wikipedia launched on Jan. 15, 2001, before the events of 9/11. While certainly not considered an academic primary source, Wikipedia is made up of freely editable content, and the articles are hyperlinked to guide readers to more information. The articles are written collaboratively by volunteers, known as Wikipedians, who are usually anonymous. It’s not a source, because Wikipedia articles can be edited by anyone with internet access), except in limited cases where editing is restricted. An 2021 article from the Cato Institute suggested that we’ve already lost the battle against disinformation on the internet, but people are currently battling over who controls the agenda on Wikipedia. Media platforms, especially in places like cable news, tend to lean right or left, and it’s constantly getting harder to filter out the nonsense. But why do people who lean right-wing distrust Wikipedia?  In 2022, a Wikipedia article on recession gained over 200,000 views. Right-wing conspiracy theorists claim Wikipedia manipulated its definition of a recession to favor the Biden administration. Conservative news platform The Daily Signal speculated about left-wing Wikipedia bias. “You see the pattern comparing political donations from different professions: Surgeons, oil workers, truck drivers, loggers, and pilots lean right; artists, bartenders, librarians, reporters, and teachers lean left,” Daily Signal writer John Stossel wrote. In April 2022, Musk bought Twitter with a plan to change everything. Musk acquired Twitter, Inc. according to an April 25, 2022 press release. The move made Twitter private and set off a firestorm of speculation, but no one could foresee the dramatic changes in store. Twitter, Inc. entered into a definitive agreement to be acquired by an entity wholly owned by Musk, for $54.20 per share in cash in a transaction valued at approximately $44 billion. Musk ran a complete overhaul of the platform formerly known as Twitter, but here’s a quick recap of some of Musk’s changes: NBC News reports that monetizing the blue check marks is fueling fake news on the Israel-Palestine war—typically old war footage or even role-player activity fronting to be new acts of violence. “People who have paid for blue checks have a financial incentive to LARP [live action role-play] as war reporters by dredging up old stories or fake footage,” Emerson T. Brooking, a researcher at the Atlantic Council’s Digital Forensics Research Lab, wrote. “Elon Musk enables this.” Time will tell if Musk can buy changes on Wikipedia as well.

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Find The Strain For You With This Quiz

High Times recently came across this new cannabinoid quiz that matches your needs and desires to specific cannabis compounds. It only takes one minute and you also get a free packet of THC Mood Gummies. We’ll explain how it works … or go ahead and take the quiz now! What’s your favorite cannabis strain? Perhaps you’re a fan of energetic sativas or sleepy indicas. But, are you sure that Wedding Cake, Gelato, or Girl Scout Cookies are really giving you the effects you’re looking for?  When we think of strains, we’re really looking at the type, strength, and combination of specific cannabinoids and terpenes found in cannabis and hemp flowers. It’s these specific compounds that give buds (and other cannabis products) their unique effects. The two best-known cannabinoids are of course THC and CBD, but there are dozens of other active compounds in hemp and cannabis. In fact, some rare cannabinoids, which occur in much smaller quantities than THC and CBD, have the opposite effects of THC. For example, THCV acts like a stimulant, increasing energy and focus while curbing the munchies. Sativas such as Durban Poison have high levels of THCV. Taken alone or with CBD (instead of THC), THCV may even promote weight loss. On the opposite end of the spectrum is CBN which has sedative properties and aids sleep, like indica Hindu Kush. Then, there’s CBG for aches and pains and CBDV for sociability etc. But, with all the acronyms, it can be difficult to remember which compound does what! That’s where this new quiz comes in. This is not just your usual CBD quiz that chooses a simple CBD oil product or a comical Buzzfeed quiz on your style of stoner personality. Instead, Rare Cannabinoid Company’s quiz finds the right combination of cannabinoids for your needs with three simple questions. Once you take the quiz, you get your results and a coupon code for a free packet of THC Mood Gummies with euphoric Delta-9-THC, depression-busting CBC oil, and stress relieving CBD oil.  Results are given by which cannabinoids will help you most, followed by recommended products. The cannabinoids are chosen from your stated needs while the product suggestions take into consideration your desired THC content and product type.  You can use this quiz to help navigate the company’s vast selection of gummies, oils, and topicals, or use it to better understand which cannabis strains to look for at your local dispensary. Rare Cannabinoid Company also recommends enhancing your own favorite THC or CBD products with specific cannabinoids according to your desired effects. THCV – Known for it’s energetic uplift and for curbing the munchies, this stimulating cannabinoid suppresses appetite while boosting focus and concentration. THCV is also being studied for nicotine and other addictions, weight loss, obesity, type 2 diabetes, and for potential antipsychotic properties. Durban Poison, an African landrace sativa that became popular in Amsterdam, is a prime example of a strain high in THCV. Other popular high THCV strains include Doug’s Varin, Jack The Ripper, Tangie, Pineapple Purps, Malawi Gold, Willie Nelson, Dutch Treat, Skunk #1, and Power Plant. However, products with high THC content may negate some THCV effects and dedicated THCV oils and extra strength THCV gummies contain much higher concentrations of THCV than you’ll ever find in a flower.  CBC – Feeling depressed? CBC cannabinoid might help. Scientific studies have found CBC to offer the most antidepressant-like effects of all non-psychoactive cannabinoids. CBC oil elevates mood by raising levels of the brain’s bliss molecule anandamide and is also good for skin health (primarily acne) and occasional inflammation. High CBC strains include 3Kings, Sour Diesel, OG Kush, Maui Dream, Blue Cherry Soda, Valentine X, Purple Candy, Birthday Cake, and Bubba Cookies, Northern Lights, and Jack Herer strain. CBC’s mood boosting properties can also cut the anxiety and paranoia triggered by too much THC consumption. This will usually work best by taking a dedicated CBC oil or low to moderate dose THC edible with high levels of CBC like Rare Cannabinoid Company’s THC Mood Gummies.  CBG – For discomfort, soreness, and joint support. Some studies say CBG may be even better than THC and CBD for pain and inflammation. CBG is also being studied for potential use against many diseases including various cancers. Most cannabis strains contain at least a little CBG, but to be considered a high-CBG strain the flower should contain around 10-15% CBG. High CBG strains include: White CBG, Jack Frost CBG Strain, Lemon Diesel CBG, White  Widow, Magic Jordan, Destroyer, Mickey Kush, Allen Wrench, Auto CBG Strain, Madras CBG, and Matterhorn CBG. You can also take CBG in a CBG tincture or gummies. Delta-9-THC – For euphoria, deep relaxation, soreness, discomfort, and nausea. All cannabis flowers contain Delta-9-THC, but those with 25% to 35+% THC are considered the most potent THC strains. The following are among the strongest Delta 9 strains available now: Godfather OG, Ghost Train Haze, Wedding Cake, Grease Monkey, Bruce Banner, Ghost OG, Pacman OG, GM-UHOH, Umami Butter, Beyond Blueberry, Runtz x Z x AC, Xeno, Triple Lindy, Blue Face, Polar Gelato, Runtz, Gorilla Glue, and Chemdawg. However, the latest studies are saying that a full spectrum mix of cannabinoids and terpenes may offer a stronger high than looking at THC content alone. CBN – Considered the most-sedative cannabinoid, CBN helps with falling asleep, staying asleep, and waking up refreshed without next-day grogginess. CBN also offers relief from discomfort and is being studied for other ailments and potential benefits to eye health. CBN cannabinoid naturally occurs when THC degrades due to heat or age. The following are considered high CBN strains, however the amount of CBN in fresh buds is nowhere near as high as you’ll find in CBN gummies, oils, or other concentrated CBN products. High CBN strains: Animal Cookies, Blackberry Kush, Tahoe OG, Banana OG, Bubble Gum, Purple Cadillac, Mr. Nice.  CBDV – Do you suffer from social anxiety? CBDV may improve sociability and memory, while reducing anxiety and irritability. CBDV is also being studied for epilepsy, autism spectrum disorder (primarily for behavioral issues, anger, and repetitive movements), ADHD, muscular dystrophy and more. It is very difficult to be sure of the amount of CBDV even in many strains considered to contain larger amounts of CBDV such as Royal CBDV strain, CBDV Auto, Euphoria, Painkiller XL, Royal Medic, Dance World, Forbidden V CBDV, and Pine Walker CBDV. To get a high quantity of CBDV, Rare Cannabinoid Company offers the world’s first pure CBDV oil tincture.  Related Article: CBD, Rare Cannabinoid Cannabidivarin Show Great Promise for Autism Spectrum Disorder CBD – For calm, balance, and inflammation after exercise. CBD is the primary cannabinoid in hemp and can offer a lot of relief without the high associated with THC and cannabis. It is also being used for seizures and studied for many potential uses. Some people enjoy a mellow mix of CBD and THC. Ratios range considerably from Ringo’s Gift (24:1 CBD/THC ratio) and ACDC (20:1 CBD/THC) to Harlequin (5:2 CBD/THC ratio) and Cannatonic (2:1 CBD/THC ratio). Meanwhile, some CBD flower strains have truly negligible amounts of THC (less than 0.3% THC). These CBD strains include: Sour Space Candy, Dough Boy, Frosted Kush, Elektra, and Harle-Tsu. Of course, there are many CBD oils, gummies, and other products on the market that contain less than 0.3% THC or Zero THC. Why did Rare Cannabinoid Company create this quiz? “We found that cannabis is often classified just by THC content, sativa vs indica, or by the sound of a strain’s name,” said a company spokesperson. “We’re beyond the times of just smoking weed to get high or taking CBD for non-psychoactive relief. We know that specific cannabinoids offer unique effects and wanted to make it easier for people to get exactly what they were looking for,” she said. “After all, cannabis users are more knowledgeable and discerning than ever and this is also a fun way to help people learn more.” For example, she explains that many people associate a fun, energetic high with a certain sativa, but they don’t realize that there are other strains and products with much higher THCV potency.  Knowing that THCV reduces hunger and helps focus and concentration, many people will choose to take a THCV gummy or oil tincture throughout the day for work or exercise. Then, they’ll combine THCV with a THC Mood Gummy or their favorite cannabis strain for a night of dancing or a party.  “By mixing and matching cannabinoids and terpenes, people can find the perfect combination for each time of day, how they feel, or what their needs are at that minute,” she said. “We hope everyone will take the quiz and that it’ll help them choose from our products or make an informed decision when they visit their dispensary,” she said. Take the quiz and don’t forget you’ll also get free THC Mood Gummies. Rare Cannabinoid Company grew out of Hawaiian Choice CBD, which was founded in Honolulu, Hawaii, in 2017. The company offers premium full and broad spectrum Hawaiian CBD as well as the largest selection of naturally occurring cannabinoid tinctures, gummies, and topicals of CBC, CBDA, CBDV, CBGA, CBG, THC, and THCV, as well as terpenes and Pet CBD. Products can be found in hundreds of locations across the United States, Asia, and South America as well as online.

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Study: Psilocybin Eases Psychological Distress in People with Childhood Trauma

We’re continuing to learn more about the potential medical applications of psychedelic substances like psilocybin, and while much of the conversation so far has been focused on conditions like treatment-resistant depression and post-traumatic stress disorder, a recent study is broadening the scope. The study, published recently in the Journal of Psychoactive Drugs, took a closer look at adverse childhood experiences as an “elevated risk for psychological distress,” specifically looking at how psilocybin may work to counter these effects. It was authored by researchers at Simon Fraser University, Athabasca University, University of British Columbia and University of Michigan. Researchers found that the use of psilocybin can help to ease psychological distress in people who had adverse experiences as children, indicating that psilocybin appeared to hold “particularly strong benefits to those with more severe childhood adversity.” “In recent years, renewed interest in psychedelic medicine has highlighted the therapeutic potential of psilocybin for those who have experienced childhood adversity,” authors mention in the study abstract. “However, recreational psilocybin use remains illegal and access to approved therapies is difficult. Such use provides an opportunity to explore the therapeutic potential of psilocybin for psychological distress among people with adverse childhood experiences.” For that reason, researchers surveyed 1,249 people in Canada over the age of 16 who completed a questionnaire used to assess experiences of childhood trauma. Participants were also asked about psilocybin use, including the last time they consumed it, frequency of psilocybin use and how strong the doses were. The study found that the effect of adverse childhood experiences on psychological distress was lower for participants who had used psilocybin in the last three months compared to those who had not. Researchers said this suggests a “potential benefit” of psilocybin in treating the psychological consequences of adverse childhood experiences. Nearly half of respondents (49.9%) said they often or always used psilocybin to address mental health or emotional challenges, and 32.3% said they sometimes used psilocybin for those reasons. Those who scored high for adverse childhood experiences were also much more likely to use psilocybin for mental health. Those who did not use psilocybin in the past 12 months cited reasons like not knowing where to get psilocybin (41.5%), being afraid of legal repercussions about consuming psilocybin (82.9%), and being worried about a bad trip or negative experience while using (48.1%). Researchers also said that there “appears to be a dose response effect,” in that more exposure to psychedelics was associated with a greater psychological effect and improvements to psychological well-being.  Authors also said that “feasibility studies suggest that psilocybin has a good safety profile and low addiction potential, particularly at low doses and even among those with complex psychiatric needs.” Still, they said that psilocybin use “outside of the care of a provider” may result in adverse experiences like bad trips. “Taken together, these findings suggest that psilocybin therapy may be potentially acceptable and may feasibly help in supporting survivors of adverse childhood experiences with particularly strong benefits to those with more severe childhood adversity,” authors said. They also noted that their findings were in line with other published search, naming a study of more than 213,000 U.S. adults which concluded that lifetime use of psilocybin was linked with lower odds of a past-year major depressive episode. It’s just one study among a growing base of research, increasingly showing the promise of psychedelic substances for mental health treatments. Along with the myriad studies showing psilocybin, and other psychedelics’, potential in treating often hard-to-treat mental health conditions, another recent study found that using psilocybin outside of a clinical setting was associated with mental health benefits including decreases in anxiety and depression. Another study looked more broadly at MDMA use with psilocybin and LSD, finding that co-using the trio of substances led some study participants to experience increased feelings of compassion, love and gratitude.

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Study Finds Highly Processed Foods Are as Addictive as Heroin, Cocaine

A new study shows that highly processed foods can be as addictive as heroin, cocaine and nicotine, leading some health experts to call for warning labels on popularly consumed snacks such as cookies and chips. The new research, which analyzed the findings of nearly 300 previous nutritional studies, was published recently by the peer-reviewed British Medical Journal. The study was headed by University of Michigan professor Ashley Gearhardt, who previously created the Yale Food Addiction Scale (YFAS) by applying the same criteria that experts use to diagnose substance addiction, including uncontrollable and excessive consumption, cravings and continued intake despite potential negative health effects. Although addiction to certain foods is not included in common diagnostic frameworks to assess mental health such as the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), research on this topic has grown rapidly in the past 20 years. Much of this research uses the YFAS, which was developed to measure food addiction by assessing DSM-5 criteria for substance use disorder in the context of food intake.  To complete the new study, researchers reviewed 281 previous studies conducted in 36 countries, which found that 14% of adults are addicted to UPFs (ultra-processed foods). The team of researchers was alarmed by the findings because of the amount of UPFs– foods such as cookies, ice cream, sausage, and sugary soft drinks and breakfast cereals– found in modern diets.  “The combination of refined carbohydrates and fats often found in UPFs seems to have a supra-additive effect on brain reward systems, above either macronutrient alone, which may increase the addictive potential of these foods,” Gearhardt and the authors of the study wrote in their new findings. As UPFs have become more common, previous studies have shown them to be associated with serious medical conditions including cancer, early death, cognitive decline and mental health issues. “Many UPFs for many people are addictive,” author Chris van Tulleken told The Guardian about the new study. “And when people experience food addiction, it is almost always to UPF products.” Exactly why UPFs cause food addictions is not yet understood. Some experts believe that rather than one particular substance being the root cause of food addictions, a combination of UPFs taken together may be the cause. While they are “not likely addictive on their own,” food additives could be “reinforcers” of the caloric effects, the researchers wrote. Natural, unprocessed foods normally have more carbohydrates or more fat, but not both. However, UPFs often have disproportionately higher levels of both fats and carbohydrates. Eating UPFs triggers a spike in dopamine that is followed by a steep decline in the neurotransmitter. The result is a cycle of craving, satisfaction and crash similar to drugs and alcohol, although not everyone is susceptible. “Addictive products are not addictive for everyone,” said van Tulleken. “Almost 90% of people can try alcohol and not develop a problematic relationship; many can try cigarettes, or even cocaine.” Past research has also found that sugary or fatty foods make healthier alternatives less appealing, a change that could have negative consequences on health, such as over-indulging and weight gain. However, avoiding UPFs has become difficult for many people because processed foods are so ubiquitous in the modern diet. As a result, the addictive properties of UPFs have led some health-conscious researchers to recommend that many foods should come with a warning similar to those for cigarettes and other tobacco products.  “Trying to quit UPFs now is like trying to quit smoking in the 1960s,” said van Tulleken. Luckily, most of the substances are safe when used in moderation, leading online medical resource Healthline to recommend that processed foods make up no more than 10% to 20% of the calories in a person’s diet. To help reach that goal, van Tulleken suggests choosing foods thoughtfully. “Ask yourself: is this really food? You can quickly move from addiction to disgust,” he said.

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Families of Deceased Loved Ones May Have Been Given Fake Ashes by Colorado Funeral Home

A Colorado funeral home is under investigation for potentially falsifying death certificates and giving fake cremated ashes to its bereaved customers after nearly 200 decaying corpses were found on its grounds. Return to Nature Funeral Home in Penrose, Colorado has been accused by at least four families of giving them fake human remains after a bad smell at the funeral home led to the police discovery of 189 rotting human bodies, almost all of which have yet to be identified according to an article by the Associated Press. Return to Nature reportedly listed third-party crematoriums on death certificates given back to bereaved family members after paying for funeral services. An Associated Press investigation culminated with the owners of said funeral homes vehemently denying having done any recent business with Return to Nature. The AP said they reviewed four death certificates provided to them by families who had used Return To Nature’s cremation services and found that none of the cremations appear to have actually happened, or at the very least did not happen at the locations provided by Return to Nature.  “My mom’s last wish was for her remains to be scattered in a place she loved, not rotting away in a building,” said Tanya Wilson, who told the Associated Press that she believes the ashes she spread in Hawaii in August were fake. “Any peace that we had, thinking that we honored her wishes, you know, was just completely ripped away from us.” According to the AP, all the death certificates they reviewed listed a crematorium owed by Wilbert Funeral Services. An attorney for Wilbert Funeral Services, Lisa Epps, said they stopped doing cremations for Return to Nature several months before the deaths listed on the provided death certificates. Epps told the AP that no less than 10 families have contacted them regarding cremations they did not perform. The owner of a second crematorium, Roselawn Funeral Home, also said they were recently contacted by a family regarding a 2021 cremation Roselawn did not perform.  Wilbert Funeral Services reportedly stopped doing business with Return to Nature because of purported financial woes. According to the AP, public records showed Return to Nature was recently the subject of an eviction notice and had records of unpaid taxes. They also recently had to pay a $21,000 settlement to Wilbert Funeral Services because they allegedly did not pay for what Epps described as “a couple hundred cremations.” The owners of Return to Nature, Jon and Carrie Hallford, have not yet been arrested but have not responded to any of the AP’s requests for comment. A member of one of the four families AP interviewed, all of whom suspect they were given dry concrete instead of human remains, said he confronted Carie Hallford about his concerns when he was originally handed the urn containing what she thought were the ashes of his mother Jesse Elliott, brother of Tanya Wilson, told the AP that when Carie Hallford handed him particularly heavy ashes, he asked her about it and Hallford said “Jesse, of course this is your mother.” Elliott and Wilson reportedly took the ashes to another funeral home director who told them the ashes looked very strange. “I’ve never seen anything that looks like that in the range of what cremated remains would typically expect to look like,” said Amber Flickinger from Platt’s Funeral Home to the AP. Another potential victim of the alleged falsifying of ashes, Michelle Johnston, told the AP she became suspicious after the news broke about all the bodies found at Return to Nature. She closely inspected her husband’s ashes and found, after applying a bit of water to them, that they turned into what she thought was concrete. Properly cremated remains do not behave this way and will remain in a brittle state, according to Faith Haug, chair of the mortuary science program at Colorado’s Arapahoe Community College. “I was kind of getting to a place where I wasn’t losing it every day,” Johnston said to the AP. “I don’t know where my husband is.” Charges against the Hallford’s and Return to Nature Funeral Home had not yet been filed at the time of publication but staggering criminal fines and a maximum two-year prison sentence are on the table, according to the AP. Colorado is known for having particularly lax laws regarding funeral services and cremations, and this is actually not the first time that concrete has potentially been substituted for human remains in Colorado. Another Colorado funeral home director was found guilty of selling body parts and fake ashes and received a 20-year prison sentence for mail fraud in January. 

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Cops Cleared of Federal Charges After Being Linked To Tipping Off Illegal Cannabis Operation

A web of lies and conspiracy is unfolding involving at least four law enforcement officers and multiple city officials in the area of Franklin County, Maine.  While two former Franklin County deputies await charges for allegedly keeping an illegal cannabis operation in Farmington, Maine in the loop of law enforcement surveillance, two other officers were cleared of federal charges after the court determined that they didn’t know why they were running plates and using government databases. The Sun Journal reports that former Wilton police officer Kevin Lemay of Farmington and former Oxford County Sheriff deputy James McLamb of Auburn were each charged by the federal government on Nov. 9, 2021, with tampering with documents. The charges alleged that they used government databases to confirm that a cannabis operation was under surveillance, and then destroyed electronic evidence. Federal prosecutors believe that Lucas Sirois—the ringleader—allegedly led a $13 million illegal cannabis operation and cops working for him on the inside, monitoring any potential investigations. Maine State Police officers and other law enforcement raided locations in Farmington and other places in Franklin County on July 21, 2020. After over a year of investigations, 11 people were indicted by a federal grand jury on Nov. 9, 2021, as well three businesses connected to Sirois. But he allegedly had several cops working for him on the inside. The two former cops were accused of running license plates per the request of Franklin County deputies Bradley Scovil and Derrick Doucette. They allegedly ran the plates to confirm that those deputies were under surveillance by law enforcement. The two former cops allegedly received cars and money in exchange for keeping the operation team in the loop.  Sirois also allegedly had city officials working for him on the inside: Former Rangeley Selectman David Burgess also admitted he accepted tens of thousands of dollars in cold, hard cash from Sirois to advocate for town decisions that benefited him and his cannabis operation. Burgess pleaded guilty in June to charges of conspiracy to distribute controlled substances, conspiracy to commit honest services fraud (bribery), and conspiracy to defraud the United States and impede and impair the Internal Revenue Service (tax fraud). His outcome was a bit less forgiving: Burgess also waived his right to appeal so long as his sentence is less than nine years. Doucette and Scovil pleaded guilty in a federal court to conspiracy to defraud and deprive residents of Franklin County of their “right to the defendants’ honest and faithful services through bribery,” and are currently awaiting sentencing. They won’t be doing any longer than five years in the slammer, though. Thanks to a plea deal, Doucette and Scovil waived their right to appeal the sentences, as long as their sentences are no longer than four years and nine months. Former officer Kevin Lemay of Farmington and former deputy James McLamb of Auburn, who also once served as town manager in Dixfield, each requested dismissal of the charges against them, saying they didn’t know the reasons for using government resources. The dismissals were granted by federal Judge Lance Walker because the government and the indictment failed to demonstrate that Lemay and McLamb were aware of a future grand jury investigation into the cannabis operation, or that their actions would affect those proceedings. That aspect is required for a conviction of tampering charge. “Mr. Lemay is pleased that the court has granted his motion and dismissed the charges against him. He has always maintained that these charges were baseless,” his attorney, Stacey Neumann, of the law firm of Murray, Plumb & Murray in Portland, Maine told The Sun Journal in an email. “From the outset, it has been our position that Mr. McLamb should not have been charged,” McLamb’s attorney Michael Turndorf of Turndorf Law in Portland wrote in an email. “This process has severely impacted Mr. McLamb’s life. I hope and trust that he can move on from this and lead a happy and productive life,” Scovil and Doucette were allegedly involved in the conspiracy from June 2019 to July 21, keeping the illegal cannabis operation  Farmington informed. Other co-defendants in the conspiracy case include Lucas Sirois,  his estranged wife Alisa Sirois, his father Robert Sirois, former Rangeley Selectman David Burgess, Brandon Dagnese, Kenneth Allen, and Ryan Nezol. Former Franklin County Assistant District Attorney Kayla Alves also pleaded guilty to federal charges of tampering with documents for her role in the conspiracy. Her license to practice law was suspended for nine months, but has since been reinstated. Alves was sentenced to two years of probation and fined $2,000 in exchange for pleading guilty. Allen and the Sirois family members pleaded not guilty and their cases are pending.

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Morocco Officials Appoint New Leader of Cannabis Agency

Mohamed El Guerrouj, who has been serving as the interim director for the Morocco National Agency for Regulating Cannabis Related Activities (ANRAC) general since September 2022, recently was granted the title of general director by Moroccan King Mohammed VI. According to Morocco World News, the announcement was made on Oct. 19 between King Mohammed VI and a council of ministers meeting to discuss the Morocco 2024 Finance Bill, as well as international agreements, and appointments to official positions.  El Guerrouj has had a lengthy career prior to his most recent cannabis appointment with plenty of experience in agriculture and development, according to Morocco World News. He graduated from the Hassan II Institute of Agronomy and Veterinary Medicine in Rabat, located on the northwestern coast of Morocco, as well as the National Institute of Agronomy in Paris-Grignon, France. In 1991, he served as the deputy director the technical department at a corporation called SOGETA, and moved on to positions as: the Ministry of Agriculture (1994), Head of the Cereals Department at the Central Directorate of Plant Production (1995), Provincial Director of Agriculture (2005), Head of the International Cooperation Division (2007), Chief of the Cabinet of the Minister of General and Economic Affairs (also in 2007), Director of Project Management at the Agency for Agricultural Development (2009), Director-General of the Agency for Agricultural Development (2013), governor of El Jadida (2017), and interim director of ANRAC (as of September 2022). Now he’s poised to lead ANRAC into the future. Moroccan Parliament initially voted to legalize medical cannabis through Law 13-21 in 2021 legalize cannabis for industrial, medical, and cosmetic purposes. ANRAC was established in 2022 to regulate all aspects of Morocco’s cannabis industry, including cultivation, certifications/licensing, marketing, processing, and manufacturing. ANRAC held its first meeting in June 2022. By October 2022, ANRAC issued the first 10 cannabis production permits, as well as authorized companies to “market and export cannabis derivatives for pharmaceutical, medical, and industrial purposes.” In doing so, the agency allows cannabis cultivation and processing to be done through agricultural collectives. In December 2022, Moroccan law enforcement dismantled a drug trafficking operation and found more than two tons of illegal cannabis. In 2021, law enforcement seized more than 191 tons of cannabis, which reflected a decrease in seizure amounts compared to that of 2020. In March of this year, Morocco officials announced that it would begin building its first testing lab, called Bio Cannat. It was one of the 10 original businesses to receive a permit from ANRAC, according to Morocco World News. Morocco has a long-standing history of cannabis cultivation and hashish production, especially in the Moroccan Rif mountains. According to a historical study published in Cannabis and Cannabinoid Research in October 2022, entitled “Origin, Early History, Cultivation, and Characteristics of the Traditional Varieties of Moroccan Cannabis sativa L.,” it’s thought that cannabis was brought to Morocco by Arab conquerors in the 10th century. Other researchers believe that it may have been introduced by travelers going on pilgrimages to Mecca, or possibly brought by African slaves. During that time, it was likely cultivated to make food, and use for textiles and making paper. What’s more certain is that cannabis cultivation was definitely happening in the Rif mountains around the early 1800s. As of the early 1900s, cannabis was mainly used for its fibers. The study claims that European narrow-leaf hemp varieties were possibly introduced to Moroccan landrace strains. In the 1960s, it’s believed that Lebanon hashish seeds, and the process of sieving (collecting cannabis resin powder) were brought to Morocco. By the early 1980s, more Lebanese cannabis strains were introduced to Morocco. Researchers noted that these strains became less common in cultivation compared to western hybrid cultivars because they were “improved, more productive, and more potent.” Cannabis prohibition began at the end of the 19th century, when sultan Hassan I created strict laws for cannabis trade and export, although he permitted five village tribes to continue cultivating. Later on, under Spanish and French control (although mainly through a monopolized tobacco grower) until 1953. Morocco became independent in 1956, and cannabis cultivation was banned. However, those villages and mountainous cultivation areas still grew the plant. The research study notes that the Rif mountains are “unfavorable” for agriculture, due to poor soil quality and a climate that leans too hot in the summer and too wet in the winter. So cultivators are limited to growing in spring and fall. According to a recent report this summer, illegal cannabis cultivation is still common in the Rif mountains. According to the United Nations Office on Drugs and Crime, that region is one of the top producers of cannabis resin in the world today. One Moroccan cultivator, named Mourad, told Al Jazeera that he learned cultivation from friends and family, although many others learned how to grow from hippies who traveled to the mountains. However, he noted his concern for switching from illegal to legal cultivation. “Official representatives came to the village in March to discuss the new bill with us and take the names of the people who might be interested,” said Mourad. “For my part, I do not really know what I am going to do. If I am forced to switch to legal production, I will, but if most of my neighbours continue to produce cannabis illegally, I will do like them.” The Moroccan Ministry of Interior estimated in 2013 that 700,000 people rely on cannabis cultivation as their livelihood.

https://hightimes.com/

From the Archives: Mr. Randall Goes to Washington (1980)

By Robert Randall Once a week I go to a pharmacy located near my home in Washington, D.C., to pick up 70 prerolled cigarettes containing two and a half ounces of marijuana. The transaction is perfectly legal. My marijuana dealer is the U.S. government. I have glaucoma, a painless, incurable eye disease. Uncontrolled, it results in blindness. In 19731 accidentally discovered that smoking marijuana significantly reduces the eye pressure associated with my disease. Armed with the medical knowledge of a tenth-grade biology student, I conducted trial-and-error tests to determine if a drug I enjoyed using could prolong my sight. By the spring of 1974 the evidence was too persuasive to ignore and I added marijuana to my complement of conventionally prescribed antiglaucoma drugs. This illicit program of medication worked reasonably well. But marijuana purchased on the black market is always expensive, often unavailable and seldom of high quality. To offset these hazards I grew my own marijuana. In August 1975 I was arrested by the District of Columbia vice squad for cultivating four marijuana plants on a secondfloor sun deck. My first impulse was to plead guilty, pay a small fine for my indiscretion and return to my career as a college professor. But within a week of my arrest I learned the federal government also knew of marijuana’s potential value in the treatment of glaucoma. Several officials actually encouraged me to continue smoking cannabis on the sly. So I freely admitted smoking marijuana but pled not guilty for reasons of medical need. To support this claim I underwent 13 days of controlled medical study in December 1975 at the Jules Stein Eye Institute at the University of California at Los Angeles. I was hospitalized for six additional days of observation in March 1976 at the Wilmer Eye Institute, John Hopkins University. Ophthalmologists at the Stein and Wilmer institutes found I was suffering a “conventional medications failure,” and submitted the same prognosis: Unable to establish adequate control over my elevated eye pressures, I would suffer a rapid progression of sight loss ending in blindness. The physicians at Wilmer proposed surgical intervention as a last resort. The research ophthalmologists at UCLA, licensed to test marijuana, recommended cannabis therapy. In May 1976 I used this information to petition federal drug-abuse agencies requesting immediate, legal access to government stocks of marijuana for medical use. Robert Rosenthal, acting chief counsel for the Drug Enforcement Administration, rejected this appeal saying, “Mr. Randall is an individual and a criminal.” He did not indicate for which of these twin sins relief was denied me. After reconsideration, the Drug Enforcement Administration decided my petition was a medical request and bucked it to the Food and Drug Administration. FDA followed DEA’s example and forwarded my appeal to the National Institute on Drug Abuse. While my petition was being dispatched into bureaucratic oblivion I went on trial in Washington, D.C., in July 1976. The pur pose of the trial was to determine if I, as an individual, were indeed “criminal.” My personal physician, Dr. Ben Fine of Washington, testified he had no firsthand knowledge of marijuana’s potential benefits (such knowledge being illegal for him to possess). He could, however, relate the primary facts of my medical history. My glaucoma was beyond the control of conventional medications; surgery presented grave risks. He concluded by telling the court, “As a physician I believe it is in the best interest of the patient to pursue avenues of possible pressure control, if they are effective, regardless of their conventionality.” Dr. Robert Hepler, then the nation’s only ophthalmologist licensed to investigate marijuana’s effect on the eye, went further. “Without marijuana he will go blind,” he told the court. “With marijuana his sight might be saved.” The U.S. attorney prosecuting me did not question the medical fact marijuana might save my sight. Nor did he bother to offer any concrete evidence to show marijuana was not safe. Instead, he.alleged marijuana could cause “(Mr. Randall’s] legs to fall off,” then added the evidence was irrelevant because there is “no constitutional right to eyesight.” After four months of deliberation Judge James Washington, Jr., ruled my use of marijuana was not criminal, but a consequence of medical “necessity” protected by law. The court declared in part, “While blindness was shown by competent medical testimony to be the otherwise inevitable result of defendant’s disease, no adverse effects from the smoking of marijuana has been demonstrated…[It] is doubtful,” the court reasoned, “that [marijuana’s] slight, speculative and undemonstrable harm could be considered more important than defendant’s right to sight.” It was the first successful case of medical “necessity” ever brought in an American court and only the 13th successful defense of necessity (a rare legal doctrine) in the 750-year history of English common law. Judge Washington’s verdict also marked the first time in 40 years that any branch of the federal government acknowledged marijuana to be a therapeutic agent. Within the month federal drug abuse agencies answered my petition by granting me legal access to government stocks of quality-controlled cannabis. I became America’s first and only legal marijuana smoker in November 1976. I smoked legal marijuana for Walter Cronkite and Tom Snyder and appeared on “To Tell the Truth.” Midnight magazine headlined, BOB SMOKES POT-AND IT’S LEGAL. The Washington Post wondered why “a man losing his sight has to rely on the courts to get the right to smoke marijuana to stave off total blindness.” Dorothy Storck, a columnist for the Philadelphia Inquirer, wrote, “One has the feeling the marijuana millennium is near.” Muckraker Jack Anderson paused between scandals to declare me “America’s most famous pot smoker,” a dubious distinction at best. I did not mind being the free world’s first legal pot smoker, but I deeply resented being the only American with medical access to marijuana. It left me feeling much like the man who makes the lifeboat and then finds he is alone. Four million Americans have glaucoma, a disease that is this nation’s second leading cause of blindness. According to the National Eye Institute 10 percent—or 400,000—of these glaucoma patients are unresponsive to conventional medications. But the question of marijuana’s medicinal use extends beyond glaucoma. Historical records and modern clinical data indicate there is a wide range of maladies that may be responsive to cannabis-based therapies. The most significant of these potentially beneficial applications for cannabis he in the plant’s ability to lower the elevated eye pressures associated with glaucoma, to reduce the nausea and vomiting generated by cancer chemotherapies and radiation treatments, and to lessen the spasticity endemic to certain types of multiple sclerosis and other neural and muscular disorders resulting in convulsion. Many patients afflicted with glaucoma, cancer and multiple sclerosis are now demanding legal access to marijuana. Growing numbers of their physicians, medical researchers and health-care professionals are also calling for marijuana’s release for medical applications, and the general public, media and politicians are increasingly supporting extensive reform measures. Recently, the National Center for Telephone Research of Pennsylvania and respected Nebraska pollster Joe B. Wilhams, found that 83 percent of the registered voters in both states approved of marijuana’s medicinal use. Farmers and ranchers in rural Nebraska were the least enthusiastic group surveyed, but by a sizable 69 percent they also supported legalizing access to cannabis for patients and physicians. On January 26, 1979, American Medical News, an American Medical Association sponsored publication distributed to physicians and health-care professionals, reported that, almost unnoticed, the question of marijuana’s legalization for therapeutic applications “is becoming one of the top medical issues this year.” The public demand for reform, while subtly expressed, has sparked a dramatic political response. In 1978, four states (New Mexico, Florida, Louisiana and Illinois) abandoned federal models of prohibition to enact laws permitting marijuana’s medical use by glaucoma and cancer patients confronting “life and sense-threatening” disability. The tempo of reform has accelerated. Fifteen additional states—Alabama, California, Colorado, Georgia, Iowa, Maine, Michigan, Nevada, North Carolina, Ohio, Oregon, Texas, Virginia, Washington and West Virginia—have enacted similar laws. Approximately 15 more states are considering measures to release marijuana for medical purposes before the end of the 1979-80 legislative session. While this mushrooming political activity is impressive, the depth of legislative support commanded by these reform actions is more instructive. The Louisiana State Senate voted 34-4 to release marijuana for medical use. In Oregon both houses of the state legislature gave unanimous consent. The conservative Florida House of Representatives approved that state’s new law by a resounding 96-6. Illinois governor James Thompson signed his state’s bill into law by calling the measure “a step forward in the practice of medicine.” Despite these innovative state laws, I still remain one of a handful of individuals with legal access to cannabis. But from my protected niche of privilege I have watched other individuals, denied similar care, suffer needlessly and go blind. Ara Cron of Wichita, Kansas, is 65, retired and suffers from glaucoma. Like many who wrote to me, Mrs. Cron wanted to know if marijuana could prolong her vision. Ara feared surgery and not without good cause. Her father had glaucoma and was blinded by ocular surgery. I could not answer her question, but instead provided her with the available research data, some general information on marijuana and the names of various federal officials. Over the next several months Mrs. Cron and her doctor contacted these officials in an effort to secure legal access to marijuana. They failed, but as a result of her efforts she attracted local press attention. Shortly after articles appeared detailing her plight she found an ounce of marijuana, a pack of cigarette rolling papers, and instructions on how to roll a joint in her mailbox. That evening Mrs. Cron’s husband, Gerald, a retired Wichita high-school principal, measured his wife’s eye pressure as he had done nightly for six years. Then Ara Cron smoked marijuana for the first time in her life. An hour later Gerald rechecked his wife’s eye pressures and found marijuana had dramatically reduced her ocular tensions. In Mrs. Cron’s case, as in mine, the reduction was significant enough to lower her pressures into the “safe” range. In the following days Mrs. Cron’s ophthalmologist conducted several informal tests and reached the same conclusion. With access to adequate supplies of quality-controlled cannabis he felt surgery might be avoided. Both he and the Crons recontacted the Food and Drug Administration, the Drug Enforcement Administration and other federal agencies to request legal supplies of marijuana. The Crons also wrote to their federal and state legislators and the Carter White House seeking assistance. They received kind responses but found no help. Within several weeks the mailbox marijuana was gone and Mrs. Cron’s eye pressure became uncontrollably elevated. Unwilling to break the law, frightened of the illegal black market, the Crons waited until they could wait no longer. By June, Mrs. Cron was forced to resort to surgery. Technically, the operation was a success. But as a consequence of surgery Ara Cron, like her father, lost most of her remaining sight. “I’m very resentful,” she told UPI months later. “There are days now I can no longer read.” The Crons do not understand why no one moved to help them. “My doctor was more than willing to treat me with marijuana in the hope surgery could be avoided or at least postponed,” Mrs. Cron explains. She sighs. “The lack of a reasonable response to his and my repeated requests for legal access to marijuana has, I feel, cost me my sight.” Ara was the first glaucoma victim I watched go blind. She has not been the last. Victims of other diseases for which marijuana offers relief have fared no better. Lynn Pierson was 25 years old and dying of cancer when I met him in December 1977. He was a tall young man who looked old beyond his years. He was bone thin and completely bald as a result of chemotherapy. The medical philosophy behind chemotherapy is both simple and savage. A patient is larger than his disease, the theory goes, so if you begin killing the patient at a cellular level, his cancer will die before he does. Chemotherapeutic agents are brutal drugs that hold out the promise of prolonged life but subject patients to violent, nearly lethal side effects. After receiving chemotherapy some cancer patients collapse or go into convulsive shock. Most suffer devastating attacks of nausea and vomit for hours or days. In some instances the trauma is so intense patients begin to vomit as soon as they enter the hospital. Lynn Pierson, like many cancer patients, received chemotherapy once, then considered abandoning the treatments, preferring death to the debilitating consequences of the cure. Fearing Lynn would abandon further treatment, his oncologist suggested he smoke marijuana to reduce the nausea and vomiting. Lynn tried marijuana, it worked, and he continued receiving his anticancer injections. “After Lynn discovered smoking marijuana made chemotherapy tolerable,” his wife Cindy explains, “he tried to get one man, a close friend, to smoke with him. The man was twice Lynn’s age and chemotherapy was killing him. But he refused to smoke marijuana, not because he doubted it worked but because it was illegal. When that man died there was just no stopping Lynn.” Pierson approached the New Mexico legislature and asked for help. His appeal received broad public support, was backed by the state’s major media, and endorsed by the New Mexico Medical Society, which called for reform. In February 1978 New Mexico adopted the nation’s first law permitting marijuana’s medical use. But repeated efforts by the state to secure “legal” marijuana from federal drug-abuse agencies proved futile. Seven months after the law’s enactment Lynn Pierson died before smoking his first legal joint or benefiting from the legislation inspired by his efforts. He was not alone. By October 1978 Dr. George Goldstein, New Mexico’s secretary for health, bluntly informed Joseph Califano, at that time secretary of the federal Department of Health, Education and Welfare, that “every patient certified by the state as eligible to receive marijuana has died before receiving the relief promised.” Goldstein put Califano on notice that “further delays on the part of FDA are neither morally nor ethically defensible.” In a Health Department report issued in January 1979 New Mexico’s chief of substance abuse, Dr. Edward Deaux, complained that “it was definitely the intent of the [state law] to establish a program through which glaucoma patients and cancer chemotherapy patients could receive marijuana. Not to establish a program to deceive these patients into believing that they were receiving marijuana when, for the purposes of satisfying federal requirements, many were not.” Upon receiving the report, the New Mexico legislature reaffirmed the state’s decision to create legal, medical channels of access to marijuana and renamed the law in honor of Lynn Pierson. While public attention is beginning to focus on the question of marijuana’s use in the treatment of glaucoma and as an adjunct to chemotherapy, patients with less dramatic but equally sinister maladies are also unable to obtain relief. Meredith S. is a stunningly beautiful young woman who appears vital and filled with life. But like a million other Americans Meredith is afflicted with the spasticity that is frequently the result of multiple sclerosis. Like glaucoma and cancer, multiple sclerosis is incurable and the available medical treatments are limited. Multiple sclerosis disrupts nerve tissue and impairs the transmission of messages to and from the brain. It eventually cripples an individual by inflicting accumulative damage to the nerves. Introduced to Meredith through a mutual friend, I was skeptical when she told me she smoked marijuana to calm the spasticity caused by her disease. “Without marijuana I was in and out of the hospital every six months, growing weaker with each attack,” she said. “But if I smoke marijuana when I feel an attack coming on, I’m able to relax until it subsides.” Current therapies for multiple sclerosis involve the use of sedating, tranquilizing and narcotic substances, many of which are highly addictive and impair a patient’s ability to function normally. Meredith’s physicians knew she smoked marijuana and did not object. “Since I started smoking marijuana,” she told me, “I’ve learned to ski. Two or three nights a week I go dancing. Those are things I never thought I’d be able to do.” Marijuana was once prescribed as an antispasmodic, but there was no modern data on the subject when I spoke to Meredith in early 1977. Yet within a month of speaking with Meredith, I received letters from three other multiple sclerosis patients who made precisely the same claims. After months of appealing to the government for help Meredith found it easier to buy marijuana illegally. Early in 1979 the first study evaluating marijuana’s utility in the treatment of multiple sclerosis was published. Seven out of nine patients given marijuana experienced a reduction in spasticity. Dr. Tod Mikuriya, one of the nation’s pioneers in the field of marijuana research, is one of the most articulate critics of present policies. In Marijuana Medical Papers, a book devoted to cannabis’s therapeutic use, published in 1973, Mikuriya charged, “Medicine in the Western World has forgotten almost all it once knew about the therapeutic properties of cannabis. The treatment of a disease is far more important than the irrational prohibitory law which forbids marijuana’s medical use.” In Mikuriya’s mind, our present problems stem from “the illegitimate removal of cannabis from medical use in 1937, and a continuing attempt by federal agencies to rewrite history by seeking to create the impression marijuana is a ‘new’ drug.” Until the introduction of morphine, marijuana was the major painkilling drug used by the Union soldiers during the Civil War. Marijuana was available by prescription in this country for nearly a century. Between 1850 and 1940, several hundred articles extolling cannabis’s healing properties appeared in reputable medical journals. As late as 1924, the Merck Manual, a popular health guide, advised the use of marijuana for conditions including “eyestrain, nausea, vomiting, digestive distress and convulsive disorders.” During this same period almost no public concern was expressed about recreational use. The Reader’s Guide to Periodical Literature, a fair measure of cultural concerns, lists no articles on cannabis between 1917 and June 1935. In 1937, however, the Federal Bureau of Narcotics encouraged Congress to enact a prohibition against marijuana’s social use. Coincidentally, Harry Anslinger, the bureau’s director, published a book titled Marijuana: The Füller Weed. Borrowing from the popular detective fiction of this period, Anslinger’s book was laced with descriptive gore ranging from rape to murder. And it was effective. The Reader’s Guide to Periodical Literature for 1937-1939 boasts more than a dozen articles condemning marijuana’s social use. This sudden, well-cultivated surge in public concern over marijuana’s potential, if unproven harms galvanized Congress. Legislation outlawing the drug’s use was drafted. The only organized resistance against the prohibition came from the medical profession. Dr. William Woodward, a lawyer-physician and the American Medical Association’s Washington lobbyist, strongly opposed legislative action. In testimony before Congress, Woodward raised two objections to the proposed prohibition. First, he argued, marijuana was not dangerous enough to warrant legal sanctions against its social use. Second, and more particular to his professional interests, Woodward told Congress that efforts to enforce a social prohibition would result in a federal regulatory scheme that would interfere with marijuana’s legitimate use and thwart scientific study into the plant’s beneficial applications. “In all you have heard thus far,” Woodward said, “no mention has been made of any excessive use of the drug by any doctor or of its excessive distribution by any pharmacist…To say, however, as has been proposed here, that the use of the drug should be prevented by a prohibitive tax, loses sight of the fact that there are substantial medical uses for cannabis.” Congress dismissed Woodward’s medical judgment and passed the Marijuana Tax Act of 1937. Though the act did not specifically prohibit marijuana’s medical use, Woodward’s fears were quickly realized. By 1938, the Federal Bureau of Narcotics had promulgated 60 pages of additional regulations covering marijuana’s use in medicine. Ostensibly, these regulations sought to discourage the diversion of medicinal cannabis into social uses. Whatever the rationale, these federally imposed controls abruptly ended marijuana’s medical use in America. Major pharmaceutical companies, including Upjohn, Eli Lilly and Sharp & Dome, abandoned promising research programs. By 1941, marijuana and 28 cannabis-based extracts were dropped from the Pharmacopoeia of the United States (a list of available medicants) after a century of accepted medical use. With the medical profession effectively neutralized, the Federal Bureau of Narcotics, a police agency of the Treasury Department, assumed absolute control of all cannabis-related study. Between 1937 and 1967 the only extensive, long-term studies of marijuana conducted in the United States were undertaken by U.S. intelligence agencies, notably the Office of Strategic Studies (OSS) and the Central Intelligence Agency, in their search for a mind-control drug. This valuable store of data on marijuana and specially prepared cannabis extracts was destroyed in 1973 when retiring CIA director Richard Helms ordered all mindcontrol files shredded. Of course, the federal government’s ironclad control over marijuana’s availability for medical study did nothing to discourage the drug’s social use. By the mid 1960s, millions of white, middle-class youths were turning on. Citing these patterns of accelerating social use, Pres. Richard Nixon called for an even more comprehensive system of federal controls. His vehicle was the Uniform Controlled Dangerous Substances Act, drafted in 1970, a year after the Supreme Court ruled the Marijuana Tax Act of 1937 was unconstitutional because it was based on double jeopardy. The Controlled Substances Act creates five distinct classes or schedules of regulation. Marijuana was placed on Schedule I, the most restrictive classification possible, along with drugs such as heroin and LSD-25. Schedule I substances, legally defined as “without accepted medical value,’’ are said to have a “high potential for abuse.” As such, the medical use of Schedule I drugs is forbidden. Research on cannabis is possible, but only after such study has been subjected to review and approval by federal drug-abuse agencies. The Drug Enforcement Administration, a progeny of the Federal Bureau of Narcotics and a police agency of the Department of Justice, administers the Controlled Substances Act. The FDA has the authority to determine a drug’s classification and the DEA enforces the determination through the power of arrest. Charged with regulating the security that surrounds Schedule I substances, the DEA can veto any program of cannabis study it deems “inappropriate.” To make marijuana available for officially sanctioned research while respecting Schedule I prohibitions against the plant’s therapeutic use, the FDA has declared marijuana a new drug. As a new drug marijuana is regulated under the Food, Drug and Cosmetics Act and researchers must comply with the agency’s complex Investigational New Drug (IND) procedures. Through the IND process, the FDA has the power to accept or reject, advance, delay, adjust or amend any proposed program of study involving marijuana. A third federal agency, the National Institute on Drug Abuse (NIDA), enjoys an exclusive monopoly over the legal cultivation of marijuana in the United States. NIDA functions as the federal government’s marijuana drugstore, and manages federal funds available for the study of drug abuse. By exercising its dual authority over marijuana supplies and research funds, NIDA has a direct influence on the design and direction of marijuana’s evaluation. Thus, to obtain access to federal stocks of cannabis, a licensed physician (or a state] must request and receive supplies of marijuana from NIDA, comply with FDA procedures and satisfy DEA Schedule I security requirements. In the past decade the federal government has spent more than $40 million on marijuana-related research. Yet less than $1 million has gone into the exploration of the potentially beneficial applications of cannabis. The vast bulk of funds and research has gone instead into a deliberate effort to scientifically and medically demonstrate that marijuana is a drug of abuse. Under the Food, Drug and Cosmetics Act, only two essential criteria qualify a substance as a medicine: First, it must be “safe” relative to the disease being treated; second, it must be “effective” in providing patients relief. Since 1970 federal drug-abuse agencies have been aware of marijuana’s potential use in the treatment of glaucoma. In that year researchers at UCLA accidentally discovered that cannabis lowered eye pressure. By September 1971 Dr. Robert Hepler communicated an outline of the UCLA findings to the Journal of the American Medical Association. Hepler wrote, “The purpose of this letter is to present preliminary data concerning the most impressive changes observed so far, namely, a substantial decrease in intraocular pressure [following the use of marijuana]. The possible implications,” he stressed, “including … therapeutic action in the treatment of glaucoma are obvious.” While Hepler continued his work without funds, other short-term studies, some unauthorized, rechecked his findings and reached the same conclusion. By 1975 Hepler informed NIDA that “marijuana produces a consistent, dose-related, clinically significant reduction in intraocular pressure.” University of Georgia at Athens researcher Dr. Keith Green, approaching the question from a different perspective, reached the same conclusion. In 1976 Green told reporters, “Marijuana is as good as, if not better than, any existing glaucoma-control drug.” The federal response to these important medical discoveries was nonexistent. Even my court victory demonstrating marijuana’s potential value in the treatment of glaucoma in 1976 failed to ignite interest. NIDA, for example, funded no glaucoma-related research in 1976, 1977 or 1978. In late 1978, the National Eye Institution (NEI) publicly announced it would fund study in this area. At present NEI tells reporters there are five federally approved programs of study. NEI fails to point out that none of these programs is funded and that three are in various stages of suspension. My private program of medical care and a second single patient constitute the remaining two studies reported by NEI. Thus, a decade after Dr. Robert Hepler discovered the link between cannabis and reduced intraocular pressure, only two glaucoma patients in the United States are legally receiving marijuana. This same pattern of neglect toward marijuana’s medical use is not confined to glaucoma, but extends across a wide range of inquiry. Dr. Norman Zinberg and Dr. Stephen Sallan, of Harvard University and the Sidney Fabrer Cancer Center respectively, became intrigued when cancer patients who smoked marijuana reported less nausea and vomiting following chemotherapy. Working without funds they clinically analyzed these “anecdotal accounts” and found marijuana was an effective antiemetic. Moreover, Zinberg and Sallan learned what to most social marijuana smokers is obvious: Marijuana stimulates the appetite. Cancer patients who smoked marijuana got the “munchies,” ate well and maintained their weight during chemotherapy. By 1975, Zinberg and Sallan reported their findings to the New England Journal of Medicine. Sallan, who has continued his research, says, “To have less anxiety, little vomiting and a better appetite takes care of many of the toxic side effects of chemotherapy.” Ann Guttentag, a 53-year-old Pennsylvania cancer patient, agrees. “Without marijuana I doubt I would have made it this far.” Mrs. Guttentag calls Compazine, the antiemetic her physician prescribed, “a real dud. It made me feel dopey and didn’t work. I would vomit for hours. But with marijuana I just take a few puffs and the nausea and vomiting goes away. My appetite returns and I raid the refrigerator.” With the help of her doctor Mrs. Guttentag is now seeking federal permission to smoke marijuana legally. “I just don’t like getting my medicine off the streets,” she says. Physicians whose patients smoke marijuana face a compromising dilemma. A Washington, D.C, oncologist who asked not to be identified laments, “What am I supposed to do? Call the cops? Tell my patients to stop smoking? Not when the patients know marijuana works and they know that I know it works. I tell them to keep puffing. I’m a doctor, not a policeman.” With all the evidence, both clinical and anecdotal, from cancer and glaucoma patients and their physicians demonstrating marijuana’s medical value, why is cannabis being denied to those who might benefit? The Drug Enforcement Administration argues it is a police agency, not a medical clearinghouse. The Food and Drug Administration describes its role as “passive” and notes it has no funds to pursue marijuana’s medical use. The National Institute on Drug Abuse says its responsibilities are limited to evaluating a drug’s “abuse potential,” not its therapeutic value. Dr. Sidney Cohen, a longtime investigator of illicit drugs, told Psychology Today in 1978, “It is not necessary to be a masochist to study marijuana, but it certainly helps.” Cohen then Used 11 federal and state agencies involved in certifying, licensing, supplying and approving his marijuana-related research. Another physician familiar with this intimidating, multibureaucratic system of controls came away with “a gut feeling the federal government does not want anything positive to come out on marijuana.” This same system of regulatory disincentives is now being deployed against those states that have legalized marijuana’s therapeutic use. Last December, Barbara Weiner, an official of the Illinois Dangerous Drug Commission, complained, “The federal government is speaking with so many different, often conflicting voices, it is nearly impossible for the states to divine an appropriate remedy.” Even if the states penetrate these regulatory barriers, their efforts may prove futile. Since 1976 the quality and quantity of federal supplies of marijuana have declined dramatically. Indeed, NIDA has so mismanaged the nation’s only legal marijuana drugstore that the federal cupboard is bare. By conservative estimate 1.5 to 2 million glaucoma and cancer patients reside in the 20 states that have already recognized marijuana’s medical value. Even under the most restrictive programs of access, 150,000 to 400,000 individuals are legally qualified to receive access to marijuana. Yet in the face of rapidly accelerating demands and despite dire warning of an impending supply crisis, NIDA actually reduced the size of the 1979 crop to a mere three acres. Federal officials continue to reassure the states that supplies are adequate to meet “any conceivable need.” But by mid 1979 the supply shortage was so acute that Dr. Seymor Perry, chairman of a Carter-appointed interagency committee, admitted that NIDA could meet the medical needs of fewer than 250 individuals. NIDA is now offering the states a consolation prize: a synthetic marijuana substitute called delta-9 THC. Despite the fact that THC is more psychoactive than real marijuana and medically inferior in terms of the relief it provides, NIDA is aggressively pushing THC. A “pot pill,” even if ineffective, is more bureaucratically pleasing than having to admit that real marijuana has real medical value. Several states, sensing these trends, have sought to avoid the red-tape runaround. If NIDA fails to make good on its promise of adequate supplies both Iowa and Michigan have threatened to use confiscated (state-owned) marijuana. Oregon may abandon federal control completely and establish an intrastate program of cultivation and distribution. Washington will not look kindly on such innovative approaches. Control over supplies of marijuana is the last means by which federal agencies can manipulate the issue and the legality of intrastate solutions is uncertain. Indeed, only one thing seems certain: Patients, promised medical access to marijuana under state laws, are being deprived of marijuana by an entrenched federal bureaucracy terrified by the prospects of change. Unable to obtain marijuana legally, seriously ill patients are resorting to the illegal, unregulated black market for relief. According to American Medical News, “thousands—and perhaps tens of thousands—of glaucoma and cancer patients across the country” are medicating themselves with marijuana. As bureaucrats bicker and interagency committees meet patients, physicians and health-care professionals are stumbling through a legal no-man’s-land, making do with what is available. Should marijuana be released for medical applications? To thousands of patients, their families and physicians, this is like asking if the pope is Polish. The federal government may pretend marijuana is as mysterious as the planet Mars, but marijuana’s ability to reduce intraocular pressure, reduce the nausea and vomiting associated with chemotherapy, and control the spasticity generated by certain types of multiple sclerosis is obvious to many patients without a day of medical training. As long as the federal government retards research it can inversely argue there is not enough data to reach a conclusion. As long as “anecdotal accounts” are greeted with the same neglect given “folk medicine” (that vast 5,000-year period immediately preceding the Marijuana Tax Act in 1937), the prohibition will remain in force. Two generations—four decades—of Americans have already suffered unnecessary pain or blindness due to federal interference in marijuana’s medical evaluation. Perhaps it is time to consider a fresh approach. The state laws now being enacted beckon toward a more reasonable and responsible policy. But these actions will remain unfulfilled gestures until substantive reform occurs in Washington and in the philosophies of abuse that dominate bureaucratic interests. Until congressional action revamps existing policies, bureaucratic assumptions centering on marijuana’s social use will continue to condemn seriously ill citizens to a choice between unnecessary physical injury and violating the law. This choice, really no choice at all, has been made. Patients are smoking marijuana. The only question is When will they be allowed to buy medication in pharmacies instead of on the streets?

https://hightimes.com/

Coffee, Cannabis & Color in Colombia

Ignoring warnings from my family and that internal fear monster informed by nothing more than movies about narcotraficantes, I board the plane for an adventure in Colombia. From the moment I see Santi’s welcoming smile as I wheel out of the baggage area, I feel my anxiety dissipating. This is going to be an amazing weekend with Wind Hill Tours, the brainchild of Damian Holman, a cannabis grower based out of Maine. He, his wife Sonja, and their business partner Santi have brought down two other “cannabis influencers” (Mary Pryor and Ace King) to assess the tour and to advise how to make the experience as amazing as possible. Scooping our baggage, Damian drives us out to Finca El Huerto. As we pull up, I look through the open air foyer and directly out to the Andes Mountains. My mouth drops open as I walk onto the splayed-out ranch estate. Bougainvillea and other flowering trees and shrubs form a semicircle around the infinity pool. The rooms of the house encircle the trees and I instantly feel wrapped in a cocoon of nature’s luxury. We relax, smoke some provided pre-rolls, and chat as the chefs prepare our first dinner. Damon tells me his vision for Wind Hill Tours as the first all-inclusive resort experience focused on wellness through the lens of cannabis. I advise him that he will be able to provide the best possible experience for his guests once his own cannabis grow is established. There is nothing like providing single-source quality as flower or hash. Though the industry is nascent—personal consumption in Colombia is decriminalized and a proposal to legalize cannabis for adults is currently in motion at the time of my visit in fall 2022—there are no growing conditions quite like those found in Colombia with its fertile volcanic soil and consistent 12/12 photoperiod. I open the pre-rolls and reroll them with rosin smeared on the paper. That’s better. At the crack of dawn the next day, I throw on a light hoodie, grab my already packed chillum, and pad out to the pool. I appreciate the lightly scented breeze that whispers through the valley songs of contentment. Facing out to the Maravelez Valley, I take a deep hit and surrender to the thick smoke which overtakes my airway, charges down into my lungs and blossoms into a pleasant warmth before sliding back through my lips. Almost immediately I feel tension releasing from my face. I had slept very well, but sometimes I need THC-laden moments like this to truly let go. The sun has just begun banishing the thick fog that had been blanketing the mountains when I finish the last of my chillum. I knock it firmly into my palm and allow the ashes to fall down before disappearing in the fragrant wind. Our first stop is a coffee finca, La Pradera. We start on a small hike to the property, crossing bamboo bridges over rushing creeks, wild coffee bushes crowding the path, and other tropical flora. Santi gives us the coffee tour, plucking unripe, yet still potent, berries for our sweet sucking pleasure. Upstairs at the coffee terrace, we sip perfectly prepared coffee, appreciate the mountains, and enjoy the sweet sounds of salsa and merengue. Newly charged with caffeine we head over to the cannabis farm, IQ&A. We are warmly welcomed and sensing our haste, the team hustles us into blue scrubs and head coverings before ushering us into the greenhouse. My face alights with joy seeing these wonderfully healthy plants. Although each household in Colombia can grow up to 20 THC plants, this legal grow is strictly CBD. We sashay through the rows; admiring the bountiful life and delight in the various terpene rich varieties. The grow is as impressive as any in California’s Emerald Triangle. We finish off the tour in a lofty perch, smoking chillum and talking about the amazing view of the Andes. Sunday morning finds me laying by the pool and puffing flower and rosin in my chillum before it is time for yoga with Jimy Betancurt. I slide through the poses with ease as I am in the zone; uncaring of any of life’s trivialities. Jimy assures us that with proper breathing and technique, we can achieve the same state of oneness and stillness that we get from our cannabis. I believe him, but I take another puff just in case. A few hours later, we pass around joints of Cholado, Bubblegum, and Bubba Kush as we head for Salento, a small town known for its wild color; as if some larger than life artist had selected all of the doors, shutters, tiles, and window sills, and splashed every surface with a different hue. We traipse through the town and up 242 stairs directly to the Alto de La Cruz lookout which gives us the best view of the town. The combination of the glaring pigments, the sun beating from above, and the effects of several joints has my head swimming in surreal, slightly off kilter awe. After a much-needed lunch, and under a persistent mist, we make our way to the nearby Valle de Corcora. We are looking to see the tallest wax palms in the world. As the Jeep barrels steadily down the road, trees and grasses sporting the most verdant leaves reach out to further entice our senses. Between the grand flora, we get glimpses of wild horses running with wild abandon; oblivious to our wide eyed stares. A few waterfalls punctuate the grand landscape. We arrive at the valley under relentless rain and I look at the proposed hiking path dubiously as the sodden ground squelches with every step. I awkwardly slip and slide my way over the fairly steep course and just when I am exhausted from the thigh workout (and mentally pooped from the lack of THC), I see the turnaround for the loop. It is a beautiful overlook of the valley and the wax palms, some of them 200 feet tall, stand erectly and in complete defiance of gravity. We have been advised not to fly the drone, but the view is just too tempting. Truthfully I too am ready to throw care to the wind and I take out a vape pen to replenish my endocannabinoid system. I plop down at the feet of a statue of Groot and I shake my head in wonder at all of the lusciousness of this whole endeavor. Colombia has been good. This adventure has been a heady expression of nature’s beauty and bounty. As THC has coursed through my body, my mind has soared wildly; buoyed not only by the cannabinoids, but also the sense of wonderment as Colombia reveals its next fascination. I have spent my time in Colombia reveling in the psychedelic experience of smelling, tasting, hearing, feeling, and seeing everything in a larger than life way. In one weekend, Wind Hill Tours has made considerable strides in its mission to provide a safe oasis for personal rejuvenation through cannabis and immersion in nature, as well as contribute to a new narrative of all that Colombia can be. This article was originally published in the March 2023 issue of High Times Magazine.

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