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Hemp News, Laws & Product Updates

A curated news hub focused on hemp regulation and policy changes, cannabinoids (CBD/Delta-8/Delta-9/hemp-derived THC), lab testing and COAs, product safety, brands, and industry trends.

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https://hightimes.com/

New Research Exploring Psychedelics as a Treatment for Anxiety in Cancer Patients

The use of psychedelics as a treatment for serious mental health conditions continues to gain traction as multiple studies focus on the psychological symptoms commonly experienced by cancer patients. In one study, researchers at the University of Washington are exploring the use of psilocybin, one of the psychoactive components of magic mushrooms, to treat anxiety experienced by patients with metastatic cancers. Other research focuses on using psychedelic therapy to help patients receiving hospice care cope with demoralization.  In a separate study at the Center for Psychedelic Medicine at the New York University (NYU) School of Medicine, researchers are conducting a clinical trial using psilocybin-assisted therapy to treat existential distress in patients with advanced-stage cancer in collaboration with colleagues at the University of Colorado. Dr. Xiaojue Hu, a psychiatrist and researcher at NYU’s Center for Psychedelic Medicine, noted that the study “is building on the same work in this area originally done at NYU in the 2010s.”  “Now, there are many other studies using psilocybin in cancer patients, including a study using psilocybin in combination with multidisciplinary palliative care to treat demoralized cancer survivors with chronic pain going on at Emory University,” she told SurvivorNet. Hu explained that psychedelic-assisted therapy could be a more sustainable and effective treatment for cancer patients than other commonly prescribed alternatives including antidepressants.  “From the psilocybin research on depression alone, we’ve seen clinically significant impact from just one or two doses of psilocybin in conjunction with therapeutic support that can last up to 14 months for some patients,” said Hu. “This is in contrast to antidepressants, which people have to take on a daily basis for potentially years, with a risk of relapse when the meds are tapered off.” Clinical research and other studies into psychedelics such as psilocybin and MDMA have shown that the drugs have potential therapeutic benefits, particularly for serious mental health conditions such as depression, PTSD, substance misuse disorders and anxiety. In January, a California biopharmaceutical company announced positive results from a clinical trial testing MDMA as a treatment for PTSD. Research published in the peer-reviewed journal JAMA Psychiatry in 2020 found that psilocybin-assisted psychotherapy was an effective and quick-acting treatment for a group of 24 participants with major depressive disorder. A separate study published in 2016 determined that psilocybin treatment produced substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer. Although the research is promising, Hu said that psychedelic-assisted therapy does not work for everyone and that further research is needed to confirm the efficacy and safety of the treatment. “Psychedelics aren’t a panacea or miracle cure for anxiety and depression, as there’s still much that’s unknown about them and there’s always the potential for adverse effects, like with any treatment,” Dr. Hu said. Hu added that research has focused on using psychedelic treatments in conjunction with multiple sessions that integrate more traditional forms of therapy. “Most of the research is also done when psychedelics, such as psilocybin, are used in the context of therapeutic support with usually two therapists, which can include up to three sessions of preparation and three sessions of integration afterwards,” she said. “So the results are not completely due to the physiologic effects of psilocybin alone, in my opinion, but must be taken into context with the therapeutic and environmental support that’s also offered.” Hu also noted that psychedelic-assisted therapy is conducted in a tightly controlled environment because the set and setting in which a patient receives the treatment can have an impact on its success. “We typically don’t expect different results if someone took their Lexapro [an antidepressant] in different moods, with different people, or in different environments, but we definitely can when it involves psychedelics,” she said. While the research continues, the use of psychedelics to treat serious mental health conditions such as anxiety and depression has yet to achieve approval from health regulators. The U.S. Department of Health and Human Services projects that the Food and Drug Administration will eventually approve MDMA and psilocybin mental health treatments, according to a letter from the department in May 2022. In 2017, the FDA granted MDMA-assisted therapy Breakthrough Therapy designation, indicating that the therapy is a significant improvement over existing treatments.  The Multidisciplinary Association for Psychedelic Studies (MAPS) predicts that an application to use MDMA to treat PTSD will be submitted to the FDA at some point in 2023, and approval could come as early as 2024. But so far, MDMA-assisted therapy has not been approved by any regulatory agency and the safety and efficacy of MDMA-assisted therapy for the treatment of PTSD have not been firmly established. “MDMA and psilocybin have the most clinical research and legal momentum behind them right now, with psilocybin already being legalized in Oregon and Colorado and MDMA phase III trials recently being completed,” said Hu.

https://hightimes.com/

Cannabeginners: Delta-8, Delta-9, Is All THC Created Equal?

Delta-8-Tetrahydrocannabinol (delta-8, also seen as ∆8-THC) is a psychoactive and intoxicating cannabinoid similar to Delta-9-Tetrahydrocannabinol (the commonly found THC we all know well). Delta-8 has seen a surge in popularity due to a legal loophole in federal regulations that limits THC to 0.3% in hemp products but has no limit for delta-8. Roger Adams and a team of researchers at the University of Illinois were the first to report partial synthesis of delta-8 in 1941. It wasn’t until 1966, when Dr. Raphael Mechoulam and his colleague Dr. Yechiel Gaoni, achieved a total synthesis of delta-8 as part of their groundbreaking work at Hebrew University. In 2002, Dr. Mechoulam applied for a patent on the conversion of CBD into delta-8 and THC through various methods, which he received in 2008, and expired in 2022. As delta-8 is an isomer of THC, they have a similar chemical structure, and the only difference is the location of a double bond between two carbons. They are both psychoactive chemicals with intoxicating, euphoric properties.  A year before Dr. Mechoulam’s patent expired was the first time the American Association of Poison Control Centers “introduced a product code specific to delta-8 THC into its National Poison Data System, allowing for the monitoring of delta-8 THC adverse events.” That would mean that, officially, 2020 was the year that the delta-8 craze began in America.  The answer to this question is complicated and depends on how you define a synthetic cannabinoid. The National Institute on Drug Abuse says that “Synthetic cannabinoids are human-made mind-altering chemicals … they are similar to chemicals found in the marijuana plant.” In order to be synthetic, a cannabinoid must be made by humans and be similar to chemicals found in the plant. In the case of delta-8, it is not similar to a cannabinoid found in the plant, it naturally is found there in very small amounts. Even though the majority of delta-8 on the market is from a lab, not the plant, the cannabinoids were still made by the plant, they were converted by humans.  The FDA’s guidance is a little more complicated. While they note delta-8 is “produced naturally by the cannabis plant,” they are clear that “concentrated amounts of delta-8 THC are typically manufactured from hemp-derived cannabidiol (CBD).” As the word “manufactured” is another way of saying something was “made,” it is ambiguous on if the FDA would view delta-8 as synthetic, and it would likely depend on where it was sourced from (a plant versus a lab).  As there are only trace amounts of delta-8 found in hemp and cannabis plants, an incalculably high percentage of delta-8 on the market was produced in a lab using the chemical conversion that Dr. Mechoulam discovered.  The publication Chemical and Engineering News (CEN) described the process as “refluxing CBD in an organic solvent, such as toluene or heptane, with p-toluenesulfonic acid or another acid that serves as a catalyst.” In a controlled, regulated environment, these reactions would be done by PhD chemists to ensure there are no harmful by-products left in products sold to consumers, but the hemp industry is notoriously under-regulated with no requirements for lab testing. Experts who spoke to CEN described the conversion process as “pretty aggressive” and noted that it used “strong acids,” and in order to neutralize those conditions they would need to use strong bases, metal catalysts, or a number of other methods. While it is possible to purify converted delta-8 from unwanted contaminants, reaction leftovers, or other by-products, most people doing those conversions are not chemists and do not properly distill it or use appropriate testing methods.  A literature review published last year found that, “No comprehensive review articles have been published that focus exclusively on Δ8-THC,” meaning their study was the first to focus on delta-8. Rather than finding delta-8 to be more harmful than THC, they found “that Δ8-THC has [a] weaker potency than Δ9-THC.” Jeffrey Raber, is a cofounder and the CEO of the Werc Shop, a California-based cannabis contract manufacturing and testing firm, who saw the potential of delta-8 several years ago. “It’s a very interesting molecule, one that has very different physiological activity depending upon the entourage,” said Raber, who is urging regulators to address the testing and purity concerns around delta-8 while still allowing safe use. The FDA received 104 reports of adverse events in people who used delta-8 products between December 1, 2020, and February 28, 2022. None of those were fatal, and the events included “hallucinations, vomiting, tremor, anxiety, dizziness, confusion, and loss of consciousness.” Poison control centers around the US received 2,362 cases of delta-8 exposure from January 1, 2021 (when delta-8 was first coded) and February 28, 2022, with one pediatric case that resulted in death.  What is not clear is if those negative experiences and that one death were caused by delta-8 itself, or the rampant impurities in delta-8 products. Due to the lack of regulations, much of the delta-8 on the market is tainted with trace amounts of other cannabinoids (possibly THC or even Delta-10-THC, another isomer) and by-products from the chemical conversion.  Kyle Boyar is a research associate at the Center for Medicinal Cannabis Research, and has reported that olivetol, a chemical precursor to THC, is a common by-product found in delta-8 products, adding “I don’t think anybody really knows the safe inhalation dose of olivetol.” As there are a range of solvents used for the conversion from CBD, there can be a wide variety of residual solvents in delta-8 products, and some, like dichloromethane and trichloroacetic acid, don’t even have standardized testing methods developed.  While 2020 was the year of the craze, what was the “why” behind the delta-8 craze? Some sources note that the delta-8 craze began only after the price of CBD plummeted, and hemp companies needed a new way to turn a profit. So was a need to stay profitable the reason behind the delta-8 craze? It certainly was a contributing factor, but the real cause of the delta-8 craze, like the CBD craze before it, was cannabis prohibition. If there was no cannabis prohibition, then everyone using less safe hemp products could use legal, lab tested cannabis products. As long as whole plant cannabis containing over a certain amount of THC is illegal, people around the world will look for ways to get around that limit and create legal loopholes, and that is all delta-8 is, a new loophole to circumvent prohibition. 

https://hightimes.com/

Throwing Shade

Christy Ai was trained from birth to move gracefully between two distinctly different worlds. Part of her life was lived in the Chinese language, among family in Asia, embracing the traditions of generations. The other part was rooted firmly in the U.S., where her parents moved to finish their studies as college post-graduates and where she was born, naturally conversant in English. Ai moved through the world as an American when in the States, as a Chinese when in China—and, it turns out, as a rebel throughout it all. A “good” girl careful to fulfill her responsibilities, Ai does things her own way—with a bit of punky mischief. She made her family in China happy by being accepted to Cornell University and taking a degree in hospitality, but her rebellious side drew her academic focus to casinos and gambling. She went into banking as a financial executive with J.P. Morgan but ended up working with alternative finance. She launched a highly lucrative business but centered it in cannabis.  Ai, 32, was accused by her family of being a drug dealer and bore the accusation with grace. She’s confident she’s not breaking any laws by growing cannabis and selling it according to California’s dictum. Plus, her grandmother has been enjoying the effects of the CBD/THC-infused balms and edibles Ai has been supplying her with since 2017. A relative with autism also appreciates how the plant products Ai gives him can calm his anxiety. Meanwhile, China itself has changed its stance slightly, beginning to experiment with hemp production and CBD development in a big way. Things generally come around to Christy Ai’s way of doing things—and when they don’t, she charts her own course. Having watched her best friend’s family suffer bankruptcy as the result of the 2008 financial crisis, Ai became interested in crypto in early 2011. Things were bad enough in the States that year, but they were even worse in China, which Ai says already constrains citizens’ access to their own money; ordinary cash transfers between Hong Kong, say, and Macao can be difficult if not impossible to complete. The idea that money you yourself worked hard to earn and save can be kept from you by the government was bewildering to Ai.  When cryptocurrency came to prominence, Ai could immediately see that it was a way to access the money you earned and grew and saved without anyone telling you if you could or not. Crypto was a way to be free.  Intrigued, Ai was an early adopter of the currency while still at J.P. Morgan. When cannabis became legal in California, she was interested in learning more and was soon active in the Discord crypto community that surrounds cannabis. Eventually she purchased a KODA NFT from the same group who created the Bored Apes Yacht Club collection. Her NFT, Koda #13528—a cuddly nine-eyed bear-like creature with fringed ears and an adorably chubby build—is one of only 10,000 “rare alien”creatures released to tease the launch of a new virtual community.  But back in 2020 when she and her partners were attempting to bootstrap the lease of an 1880s building in downtown Los Angeles, a 100,000-square-foot former adult diaper factory that they intended to revamp into a state-of-the-art cannabis grow facility, Ai hadn’t yet connected all the dots that would become the road map to her future. “We had our operating license in place and all of the other missing pieces, but the one thing that was an issue was funding,” she says, still sounding frustrated. “And it wasn’t just funding in terms of the money needed to build an entire cultivation, but it was also: how will people pay you? How do you pay rent? Landlords don’t take bags of cash. Utility companies don’t take bags of cash. I realized cannabis was really the true, modern day, unbanked industry for a First World country. I thought about it until the answer occurred to me: The answer was crypto.” Harnessing the power of crypto allowed Ai and her partners to procure and establish a robust $10 million grow facility known as Vangarde Cultivation in that old building in DTLA. Today they operate under a social equity license to provide some 30 employees with full time employment. Operations are focused on small-batch craft cannabis that is hand-raised, hand-harvested, and stick-trimmed by hand. Each of the nine grow rooms is personally overseen by a specific individual who is charged with the success of the flower inside. For her part, Ai sees herself as being personally charged with the success of each specific human individual inside the building. She and her business partner provide services like apprenticeships and training, housing and even cars to employees who may have sacrificed due to their involvement in the cannabis industry. “We give a lot back to our employees in terms of literally helping to get new apartments and cars because you don’t have a credit score when you work in the cannabis industry,” Ai says. Not content with merely co-owning Vangarde, one of the largest indoor growing facilities in Los Angeles, Ai struck out on her own to found The Otherside flower brand (as in: The grass is always greener on . . .) in 2022. Her KODA NFT proudly acts as the brand’s mascot and its silent voice. The Otherside’s small-batch craft cannabis is currently found in 13 California dispensaries—and counting. The brand’s three proprietary strains include perennial best-seller Sugarberry Cream, a trichrome-rich flower that bursts with lemon meringue and cherry-touched cotton candy flavors, as well as Bittersweet Jealousy, and Sunrise Papaya.  Ai’s KODA NFT is adapted to be slightly different for each strain it represents. But here’s the secret: If you look closely, you’ll see that the KODA is making a different American Sign Language (ASL) sign for each strain.  Ai explains: “Our spirit is reflected through the infamous KODA NFT that pays homage to the war against cannabis prohibition and celebrates the power of cryptocurrency. This KODA is our secret little ‘eff you’ message to everyone who tries to keep the industry down and to all the discrimination we still face as an industry today.” Here’s the code: According to Ai, who is always up for a bit of disruption and is known for swimming against the stream, this is a clever way of throwing shade while nodding to the ASL community and indulging in a bit of mystery. “I thought of it as a code, as a secret message,” Ai says. “We wanted to incorporate if-you-know-you-know messaging. That’s why it’s silent, like ‘They’ve been judging us the entire time and now we’re just silently judging them back.” Find The Otherside online at otherside-la.com

https://hightimes.com/

Elon Musk Offers $1 Billion to Wikipedia to Change Its Name to ‘Dickipedia’

Billionaire Elon Musk floated spending $1 billion on a joke—specifically to rename Wikipedia as “Dickipedia,” while right-wing distrust in the open-source database grows.  Musk broke the internet last year when he bought Twitter for $44 billion dollars and whittled it down to the bones, transforming it into a monetizing mill that charges for blue check marks, subscriptions to verified accounts, and the platform might charge all users $1 per month. Now Twitter/X is only worth one-tenth the amount it was worth when Musk bought it. Fortune reported last September that Twitter/X has lost 90% of its value and could be worth just $4 billion.   He’s at it again, now with Wikipedia. On Oct. 22, billionaire Musk posted a screenshot on X, formerly Twitter, showing that “Wikipedia is not for sale.” He then offered the database $1 billion if they change the Wikipedia name to Dickipedia, even if they quickly change it back. “Have you ever wondered why the Wikimedia Foundation wants so much money? It certainly isn’t needed to operate Wikipedia,” Musk posited. “You can literally fit a copy of the entire text on your phone! So, what’s the money for? Inquiring minds want to know.”  X users used the “Add Context” feature on the app to answer his question. “Expenses: $146m – 43-45% engineering improvements, product development, design and research, and legal support – 31-32% grants, projects, trainings, tools for contributor capacity, and support for the legal defense of editors – 13% Administration – 11-12% Fundraising,” users wrote. The next day, Musk posted on X that he’s offering $1 billion to the platform if they change its name to “Dickipedia.” “I will give them a billion dollars if they change their name to Dickipedia,” he posted, adding that they could change the name back. He replied to his post, adding “In the interests of accuracy.” Wikipedia is the world’s largest database, and is using the first Google result to pop up when users ask the internet any question. Wikipedia launched on Jan. 15, 2001, before the events of 9/11. While certainly not considered an academic primary source, Wikipedia is made up of freely editable content, and the articles are hyperlinked to guide readers to more information. The articles are written collaboratively by volunteers, known as Wikipedians, who are usually anonymous. It’s not a source, because Wikipedia articles can be edited by anyone with internet access), except in limited cases where editing is restricted. An 2021 article from the Cato Institute suggested that we’ve already lost the battle against disinformation on the internet, but people are currently battling over who controls the agenda on Wikipedia. Media platforms, especially in places like cable news, tend to lean right or left, and it’s constantly getting harder to filter out the nonsense. But why do people who lean right-wing distrust Wikipedia?  In 2022, a Wikipedia article on recession gained over 200,000 views. Right-wing conspiracy theorists claim Wikipedia manipulated its definition of a recession to favor the Biden administration. Conservative news platform The Daily Signal speculated about left-wing Wikipedia bias. “You see the pattern comparing political donations from different professions: Surgeons, oil workers, truck drivers, loggers, and pilots lean right; artists, bartenders, librarians, reporters, and teachers lean left,” Daily Signal writer John Stossel wrote. In April 2022, Musk bought Twitter with a plan to change everything. Musk acquired Twitter, Inc. according to an April 25, 2022 press release. The move made Twitter private and set off a firestorm of speculation, but no one could foresee the dramatic changes in store. Twitter, Inc. entered into a definitive agreement to be acquired by an entity wholly owned by Musk, for $54.20 per share in cash in a transaction valued at approximately $44 billion. Musk ran a complete overhaul of the platform formerly known as Twitter, but here’s a quick recap of some of Musk’s changes: NBC News reports that monetizing the blue check marks is fueling fake news on the Israel-Palestine war—typically old war footage or even role-player activity fronting to be new acts of violence. “People who have paid for blue checks have a financial incentive to LARP [live action role-play] as war reporters by dredging up old stories or fake footage,” Emerson T. Brooking, a researcher at the Atlantic Council’s Digital Forensics Research Lab, wrote. “Elon Musk enables this.” Time will tell if Musk can buy changes on Wikipedia as well.

https://hightimes.com/

Find The Strain For You With This Quiz

High Times recently came across this new cannabinoid quiz that matches your needs and desires to specific cannabis compounds. It only takes one minute and you also get a free packet of THC Mood Gummies. We’ll explain how it works … or go ahead and take the quiz now! What’s your favorite cannabis strain? Perhaps you’re a fan of energetic sativas or sleepy indicas. But, are you sure that Wedding Cake, Gelato, or Girl Scout Cookies are really giving you the effects you’re looking for?  When we think of strains, we’re really looking at the type, strength, and combination of specific cannabinoids and terpenes found in cannabis and hemp flowers. It’s these specific compounds that give buds (and other cannabis products) their unique effects. The two best-known cannabinoids are of course THC and CBD, but there are dozens of other active compounds in hemp and cannabis. In fact, some rare cannabinoids, which occur in much smaller quantities than THC and CBD, have the opposite effects of THC. For example, THCV acts like a stimulant, increasing energy and focus while curbing the munchies. Sativas such as Durban Poison have high levels of THCV. Taken alone or with CBD (instead of THC), THCV may even promote weight loss. On the opposite end of the spectrum is CBN which has sedative properties and aids sleep, like indica Hindu Kush. Then, there’s CBG for aches and pains and CBDV for sociability etc. But, with all the acronyms, it can be difficult to remember which compound does what! That’s where this new quiz comes in. This is not just your usual CBD quiz that chooses a simple CBD oil product or a comical Buzzfeed quiz on your style of stoner personality. Instead, Rare Cannabinoid Company’s quiz finds the right combination of cannabinoids for your needs with three simple questions. Once you take the quiz, you get your results and a coupon code for a free packet of THC Mood Gummies with euphoric Delta-9-THC, depression-busting CBC oil, and stress relieving CBD oil.  Results are given by which cannabinoids will help you most, followed by recommended products. The cannabinoids are chosen from your stated needs while the product suggestions take into consideration your desired THC content and product type.  You can use this quiz to help navigate the company’s vast selection of gummies, oils, and topicals, or use it to better understand which cannabis strains to look for at your local dispensary. Rare Cannabinoid Company also recommends enhancing your own favorite THC or CBD products with specific cannabinoids according to your desired effects. THCV – Known for it’s energetic uplift and for curbing the munchies, this stimulating cannabinoid suppresses appetite while boosting focus and concentration. THCV is also being studied for nicotine and other addictions, weight loss, obesity, type 2 diabetes, and for potential antipsychotic properties. Durban Poison, an African landrace sativa that became popular in Amsterdam, is a prime example of a strain high in THCV. Other popular high THCV strains include Doug’s Varin, Jack The Ripper, Tangie, Pineapple Purps, Malawi Gold, Willie Nelson, Dutch Treat, Skunk #1, and Power Plant. However, products with high THC content may negate some THCV effects and dedicated THCV oils and extra strength THCV gummies contain much higher concentrations of THCV than you’ll ever find in a flower.  CBC – Feeling depressed? CBC cannabinoid might help. Scientific studies have found CBC to offer the most antidepressant-like effects of all non-psychoactive cannabinoids. CBC oil elevates mood by raising levels of the brain’s bliss molecule anandamide and is also good for skin health (primarily acne) and occasional inflammation. High CBC strains include 3Kings, Sour Diesel, OG Kush, Maui Dream, Blue Cherry Soda, Valentine X, Purple Candy, Birthday Cake, and Bubba Cookies, Northern Lights, and Jack Herer strain. CBC’s mood boosting properties can also cut the anxiety and paranoia triggered by too much THC consumption. This will usually work best by taking a dedicated CBC oil or low to moderate dose THC edible with high levels of CBC like Rare Cannabinoid Company’s THC Mood Gummies.  CBG – For discomfort, soreness, and joint support. Some studies say CBG may be even better than THC and CBD for pain and inflammation. CBG is also being studied for potential use against many diseases including various cancers. Most cannabis strains contain at least a little CBG, but to be considered a high-CBG strain the flower should contain around 10-15% CBG. High CBG strains include: White CBG, Jack Frost CBG Strain, Lemon Diesel CBG, White  Widow, Magic Jordan, Destroyer, Mickey Kush, Allen Wrench, Auto CBG Strain, Madras CBG, and Matterhorn CBG. You can also take CBG in a CBG tincture or gummies. Delta-9-THC – For euphoria, deep relaxation, soreness, discomfort, and nausea. All cannabis flowers contain Delta-9-THC, but those with 25% to 35+% THC are considered the most potent THC strains. The following are among the strongest Delta 9 strains available now: Godfather OG, Ghost Train Haze, Wedding Cake, Grease Monkey, Bruce Banner, Ghost OG, Pacman OG, GM-UHOH, Umami Butter, Beyond Blueberry, Runtz x Z x AC, Xeno, Triple Lindy, Blue Face, Polar Gelato, Runtz, Gorilla Glue, and Chemdawg. However, the latest studies are saying that a full spectrum mix of cannabinoids and terpenes may offer a stronger high than looking at THC content alone. CBN – Considered the most-sedative cannabinoid, CBN helps with falling asleep, staying asleep, and waking up refreshed without next-day grogginess. CBN also offers relief from discomfort and is being studied for other ailments and potential benefits to eye health. CBN cannabinoid naturally occurs when THC degrades due to heat or age. The following are considered high CBN strains, however the amount of CBN in fresh buds is nowhere near as high as you’ll find in CBN gummies, oils, or other concentrated CBN products. High CBN strains: Animal Cookies, Blackberry Kush, Tahoe OG, Banana OG, Bubble Gum, Purple Cadillac, Mr. Nice.  CBDV – Do you suffer from social anxiety? CBDV may improve sociability and memory, while reducing anxiety and irritability. CBDV is also being studied for epilepsy, autism spectrum disorder (primarily for behavioral issues, anger, and repetitive movements), ADHD, muscular dystrophy and more. It is very difficult to be sure of the amount of CBDV even in many strains considered to contain larger amounts of CBDV such as Royal CBDV strain, CBDV Auto, Euphoria, Painkiller XL, Royal Medic, Dance World, Forbidden V CBDV, and Pine Walker CBDV. To get a high quantity of CBDV, Rare Cannabinoid Company offers the world’s first pure CBDV oil tincture.  Related Article: CBD, Rare Cannabinoid Cannabidivarin Show Great Promise for Autism Spectrum Disorder CBD – For calm, balance, and inflammation after exercise. CBD is the primary cannabinoid in hemp and can offer a lot of relief without the high associated with THC and cannabis. It is also being used for seizures and studied for many potential uses. Some people enjoy a mellow mix of CBD and THC. Ratios range considerably from Ringo’s Gift (24:1 CBD/THC ratio) and ACDC (20:1 CBD/THC) to Harlequin (5:2 CBD/THC ratio) and Cannatonic (2:1 CBD/THC ratio). Meanwhile, some CBD flower strains have truly negligible amounts of THC (less than 0.3% THC). These CBD strains include: Sour Space Candy, Dough Boy, Frosted Kush, Elektra, and Harle-Tsu. Of course, there are many CBD oils, gummies, and other products on the market that contain less than 0.3% THC or Zero THC. Why did Rare Cannabinoid Company create this quiz? “We found that cannabis is often classified just by THC content, sativa vs indica, or by the sound of a strain’s name,” said a company spokesperson. “We’re beyond the times of just smoking weed to get high or taking CBD for non-psychoactive relief. We know that specific cannabinoids offer unique effects and wanted to make it easier for people to get exactly what they were looking for,” she said. “After all, cannabis users are more knowledgeable and discerning than ever and this is also a fun way to help people learn more.” For example, she explains that many people associate a fun, energetic high with a certain sativa, but they don’t realize that there are other strains and products with much higher THCV potency.  Knowing that THCV reduces hunger and helps focus and concentration, many people will choose to take a THCV gummy or oil tincture throughout the day for work or exercise. Then, they’ll combine THCV with a THC Mood Gummy or their favorite cannabis strain for a night of dancing or a party.  “By mixing and matching cannabinoids and terpenes, people can find the perfect combination for each time of day, how they feel, or what their needs are at that minute,” she said. “We hope everyone will take the quiz and that it’ll help them choose from our products or make an informed decision when they visit their dispensary,” she said. Take the quiz and don’t forget you’ll also get free THC Mood Gummies. Rare Cannabinoid Company grew out of Hawaiian Choice CBD, which was founded in Honolulu, Hawaii, in 2017. The company offers premium full and broad spectrum Hawaiian CBD as well as the largest selection of naturally occurring cannabinoid tinctures, gummies, and topicals of CBC, CBDA, CBDV, CBGA, CBG, THC, and THCV, as well as terpenes and Pet CBD. Products can be found in hundreds of locations across the United States, Asia, and South America as well as online.

https://hightimes.com/

Study: Psilocybin Eases Psychological Distress in People with Childhood Trauma

We’re continuing to learn more about the potential medical applications of psychedelic substances like psilocybin, and while much of the conversation so far has been focused on conditions like treatment-resistant depression and post-traumatic stress disorder, a recent study is broadening the scope. The study, published recently in the Journal of Psychoactive Drugs, took a closer look at adverse childhood experiences as an “elevated risk for psychological distress,” specifically looking at how psilocybin may work to counter these effects. It was authored by researchers at Simon Fraser University, Athabasca University, University of British Columbia and University of Michigan. Researchers found that the use of psilocybin can help to ease psychological distress in people who had adverse experiences as children, indicating that psilocybin appeared to hold “particularly strong benefits to those with more severe childhood adversity.” “In recent years, renewed interest in psychedelic medicine has highlighted the therapeutic potential of psilocybin for those who have experienced childhood adversity,” authors mention in the study abstract. “However, recreational psilocybin use remains illegal and access to approved therapies is difficult. Such use provides an opportunity to explore the therapeutic potential of psilocybin for psychological distress among people with adverse childhood experiences.” For that reason, researchers surveyed 1,249 people in Canada over the age of 16 who completed a questionnaire used to assess experiences of childhood trauma. Participants were also asked about psilocybin use, including the last time they consumed it, frequency of psilocybin use and how strong the doses were. The study found that the effect of adverse childhood experiences on psychological distress was lower for participants who had used psilocybin in the last three months compared to those who had not. Researchers said this suggests a “potential benefit” of psilocybin in treating the psychological consequences of adverse childhood experiences. Nearly half of respondents (49.9%) said they often or always used psilocybin to address mental health or emotional challenges, and 32.3% said they sometimes used psilocybin for those reasons. Those who scored high for adverse childhood experiences were also much more likely to use psilocybin for mental health. Those who did not use psilocybin in the past 12 months cited reasons like not knowing where to get psilocybin (41.5%), being afraid of legal repercussions about consuming psilocybin (82.9%), and being worried about a bad trip or negative experience while using (48.1%). Researchers also said that there “appears to be a dose response effect,” in that more exposure to psychedelics was associated with a greater psychological effect and improvements to psychological well-being.  Authors also said that “feasibility studies suggest that psilocybin has a good safety profile and low addiction potential, particularly at low doses and even among those with complex psychiatric needs.” Still, they said that psilocybin use “outside of the care of a provider” may result in adverse experiences like bad trips. “Taken together, these findings suggest that psilocybin therapy may be potentially acceptable and may feasibly help in supporting survivors of adverse childhood experiences with particularly strong benefits to those with more severe childhood adversity,” authors said. They also noted that their findings were in line with other published search, naming a study of more than 213,000 U.S. adults which concluded that lifetime use of psilocybin was linked with lower odds of a past-year major depressive episode. It’s just one study among a growing base of research, increasingly showing the promise of psychedelic substances for mental health treatments. Along with the myriad studies showing psilocybin, and other psychedelics’, potential in treating often hard-to-treat mental health conditions, another recent study found that using psilocybin outside of a clinical setting was associated with mental health benefits including decreases in anxiety and depression. Another study looked more broadly at MDMA use with psilocybin and LSD, finding that co-using the trio of substances led some study participants to experience increased feelings of compassion, love and gratitude.

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Study Finds Highly Processed Foods Are as Addictive as Heroin, Cocaine

A new study shows that highly processed foods can be as addictive as heroin, cocaine and nicotine, leading some health experts to call for warning labels on popularly consumed snacks such as cookies and chips. The new research, which analyzed the findings of nearly 300 previous nutritional studies, was published recently by the peer-reviewed British Medical Journal. The study was headed by University of Michigan professor Ashley Gearhardt, who previously created the Yale Food Addiction Scale (YFAS) by applying the same criteria that experts use to diagnose substance addiction, including uncontrollable and excessive consumption, cravings and continued intake despite potential negative health effects. Although addiction to certain foods is not included in common diagnostic frameworks to assess mental health such as the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), research on this topic has grown rapidly in the past 20 years. Much of this research uses the YFAS, which was developed to measure food addiction by assessing DSM-5 criteria for substance use disorder in the context of food intake.  To complete the new study, researchers reviewed 281 previous studies conducted in 36 countries, which found that 14% of adults are addicted to UPFs (ultra-processed foods). The team of researchers was alarmed by the findings because of the amount of UPFs– foods such as cookies, ice cream, sausage, and sugary soft drinks and breakfast cereals– found in modern diets.  “The combination of refined carbohydrates and fats often found in UPFs seems to have a supra-additive effect on brain reward systems, above either macronutrient alone, which may increase the addictive potential of these foods,” Gearhardt and the authors of the study wrote in their new findings. As UPFs have become more common, previous studies have shown them to be associated with serious medical conditions including cancer, early death, cognitive decline and mental health issues. “Many UPFs for many people are addictive,” author Chris van Tulleken told The Guardian about the new study. “And when people experience food addiction, it is almost always to UPF products.” Exactly why UPFs cause food addictions is not yet understood. Some experts believe that rather than one particular substance being the root cause of food addictions, a combination of UPFs taken together may be the cause. While they are “not likely addictive on their own,” food additives could be “reinforcers” of the caloric effects, the researchers wrote. Natural, unprocessed foods normally have more carbohydrates or more fat, but not both. However, UPFs often have disproportionately higher levels of both fats and carbohydrates. Eating UPFs triggers a spike in dopamine that is followed by a steep decline in the neurotransmitter. The result is a cycle of craving, satisfaction and crash similar to drugs and alcohol, although not everyone is susceptible. “Addictive products are not addictive for everyone,” said van Tulleken. “Almost 90% of people can try alcohol and not develop a problematic relationship; many can try cigarettes, or even cocaine.” Past research has also found that sugary or fatty foods make healthier alternatives less appealing, a change that could have negative consequences on health, such as over-indulging and weight gain. However, avoiding UPFs has become difficult for many people because processed foods are so ubiquitous in the modern diet. As a result, the addictive properties of UPFs have led some health-conscious researchers to recommend that many foods should come with a warning similar to those for cigarettes and other tobacco products.  “Trying to quit UPFs now is like trying to quit smoking in the 1960s,” said van Tulleken. Luckily, most of the substances are safe when used in moderation, leading online medical resource Healthline to recommend that processed foods make up no more than 10% to 20% of the calories in a person’s diet. To help reach that goal, van Tulleken suggests choosing foods thoughtfully. “Ask yourself: is this really food? You can quickly move from addiction to disgust,” he said.

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Families of Deceased Loved Ones May Have Been Given Fake Ashes by Colorado Funeral Home

A Colorado funeral home is under investigation for potentially falsifying death certificates and giving fake cremated ashes to its bereaved customers after nearly 200 decaying corpses were found on its grounds. Return to Nature Funeral Home in Penrose, Colorado has been accused by at least four families of giving them fake human remains after a bad smell at the funeral home led to the police discovery of 189 rotting human bodies, almost all of which have yet to be identified according to an article by the Associated Press. Return to Nature reportedly listed third-party crematoriums on death certificates given back to bereaved family members after paying for funeral services. An Associated Press investigation culminated with the owners of said funeral homes vehemently denying having done any recent business with Return to Nature. The AP said they reviewed four death certificates provided to them by families who had used Return To Nature’s cremation services and found that none of the cremations appear to have actually happened, or at the very least did not happen at the locations provided by Return to Nature.  “My mom’s last wish was for her remains to be scattered in a place she loved, not rotting away in a building,” said Tanya Wilson, who told the Associated Press that she believes the ashes she spread in Hawaii in August were fake. “Any peace that we had, thinking that we honored her wishes, you know, was just completely ripped away from us.” According to the AP, all the death certificates they reviewed listed a crematorium owed by Wilbert Funeral Services. An attorney for Wilbert Funeral Services, Lisa Epps, said they stopped doing cremations for Return to Nature several months before the deaths listed on the provided death certificates. Epps told the AP that no less than 10 families have contacted them regarding cremations they did not perform. The owner of a second crematorium, Roselawn Funeral Home, also said they were recently contacted by a family regarding a 2021 cremation Roselawn did not perform.  Wilbert Funeral Services reportedly stopped doing business with Return to Nature because of purported financial woes. According to the AP, public records showed Return to Nature was recently the subject of an eviction notice and had records of unpaid taxes. They also recently had to pay a $21,000 settlement to Wilbert Funeral Services because they allegedly did not pay for what Epps described as “a couple hundred cremations.” The owners of Return to Nature, Jon and Carrie Hallford, have not yet been arrested but have not responded to any of the AP’s requests for comment. A member of one of the four families AP interviewed, all of whom suspect they were given dry concrete instead of human remains, said he confronted Carie Hallford about his concerns when he was originally handed the urn containing what she thought were the ashes of his mother Jesse Elliott, brother of Tanya Wilson, told the AP that when Carie Hallford handed him particularly heavy ashes, he asked her about it and Hallford said “Jesse, of course this is your mother.” Elliott and Wilson reportedly took the ashes to another funeral home director who told them the ashes looked very strange. “I’ve never seen anything that looks like that in the range of what cremated remains would typically expect to look like,” said Amber Flickinger from Platt’s Funeral Home to the AP. Another potential victim of the alleged falsifying of ashes, Michelle Johnston, told the AP she became suspicious after the news broke about all the bodies found at Return to Nature. She closely inspected her husband’s ashes and found, after applying a bit of water to them, that they turned into what she thought was concrete. Properly cremated remains do not behave this way and will remain in a brittle state, according to Faith Haug, chair of the mortuary science program at Colorado’s Arapahoe Community College. “I was kind of getting to a place where I wasn’t losing it every day,” Johnston said to the AP. “I don’t know where my husband is.” Charges against the Hallford’s and Return to Nature Funeral Home had not yet been filed at the time of publication but staggering criminal fines and a maximum two-year prison sentence are on the table, according to the AP. Colorado is known for having particularly lax laws regarding funeral services and cremations, and this is actually not the first time that concrete has potentially been substituted for human remains in Colorado. Another Colorado funeral home director was found guilty of selling body parts and fake ashes and received a 20-year prison sentence for mail fraud in January. 

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Cops Cleared of Federal Charges After Being Linked To Tipping Off Illegal Cannabis Operation

A web of lies and conspiracy is unfolding involving at least four law enforcement officers and multiple city officials in the area of Franklin County, Maine.  While two former Franklin County deputies await charges for allegedly keeping an illegal cannabis operation in Farmington, Maine in the loop of law enforcement surveillance, two other officers were cleared of federal charges after the court determined that they didn’t know why they were running plates and using government databases. The Sun Journal reports that former Wilton police officer Kevin Lemay of Farmington and former Oxford County Sheriff deputy James McLamb of Auburn were each charged by the federal government on Nov. 9, 2021, with tampering with documents. The charges alleged that they used government databases to confirm that a cannabis operation was under surveillance, and then destroyed electronic evidence. Federal prosecutors believe that Lucas Sirois—the ringleader—allegedly led a $13 million illegal cannabis operation and cops working for him on the inside, monitoring any potential investigations. Maine State Police officers and other law enforcement raided locations in Farmington and other places in Franklin County on July 21, 2020. After over a year of investigations, 11 people were indicted by a federal grand jury on Nov. 9, 2021, as well three businesses connected to Sirois. But he allegedly had several cops working for him on the inside. The two former cops were accused of running license plates per the request of Franklin County deputies Bradley Scovil and Derrick Doucette. They allegedly ran the plates to confirm that those deputies were under surveillance by law enforcement. The two former cops allegedly received cars and money in exchange for keeping the operation team in the loop.  Sirois also allegedly had city officials working for him on the inside: Former Rangeley Selectman David Burgess also admitted he accepted tens of thousands of dollars in cold, hard cash from Sirois to advocate for town decisions that benefited him and his cannabis operation. Burgess pleaded guilty in June to charges of conspiracy to distribute controlled substances, conspiracy to commit honest services fraud (bribery), and conspiracy to defraud the United States and impede and impair the Internal Revenue Service (tax fraud). His outcome was a bit less forgiving: Burgess also waived his right to appeal so long as his sentence is less than nine years. Doucette and Scovil pleaded guilty in a federal court to conspiracy to defraud and deprive residents of Franklin County of their “right to the defendants’ honest and faithful services through bribery,” and are currently awaiting sentencing. They won’t be doing any longer than five years in the slammer, though. Thanks to a plea deal, Doucette and Scovil waived their right to appeal the sentences, as long as their sentences are no longer than four years and nine months. Former officer Kevin Lemay of Farmington and former deputy James McLamb of Auburn, who also once served as town manager in Dixfield, each requested dismissal of the charges against them, saying they didn’t know the reasons for using government resources. The dismissals were granted by federal Judge Lance Walker because the government and the indictment failed to demonstrate that Lemay and McLamb were aware of a future grand jury investigation into the cannabis operation, or that their actions would affect those proceedings. That aspect is required for a conviction of tampering charge. “Mr. Lemay is pleased that the court has granted his motion and dismissed the charges against him. He has always maintained that these charges were baseless,” his attorney, Stacey Neumann, of the law firm of Murray, Plumb & Murray in Portland, Maine told The Sun Journal in an email. “From the outset, it has been our position that Mr. McLamb should not have been charged,” McLamb’s attorney Michael Turndorf of Turndorf Law in Portland wrote in an email. “This process has severely impacted Mr. McLamb’s life. I hope and trust that he can move on from this and lead a happy and productive life,” Scovil and Doucette were allegedly involved in the conspiracy from June 2019 to July 21, keeping the illegal cannabis operation  Farmington informed. Other co-defendants in the conspiracy case include Lucas Sirois,  his estranged wife Alisa Sirois, his father Robert Sirois, former Rangeley Selectman David Burgess, Brandon Dagnese, Kenneth Allen, and Ryan Nezol. Former Franklin County Assistant District Attorney Kayla Alves also pleaded guilty to federal charges of tampering with documents for her role in the conspiracy. Her license to practice law was suspended for nine months, but has since been reinstated. Alves was sentenced to two years of probation and fined $2,000 in exchange for pleading guilty. Allen and the Sirois family members pleaded not guilty and their cases are pending.

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Morocco Officials Appoint New Leader of Cannabis Agency

Mohamed El Guerrouj, who has been serving as the interim director for the Morocco National Agency for Regulating Cannabis Related Activities (ANRAC) general since September 2022, recently was granted the title of general director by Moroccan King Mohammed VI. According to Morocco World News, the announcement was made on Oct. 19 between King Mohammed VI and a council of ministers meeting to discuss the Morocco 2024 Finance Bill, as well as international agreements, and appointments to official positions.  El Guerrouj has had a lengthy career prior to his most recent cannabis appointment with plenty of experience in agriculture and development, according to Morocco World News. He graduated from the Hassan II Institute of Agronomy and Veterinary Medicine in Rabat, located on the northwestern coast of Morocco, as well as the National Institute of Agronomy in Paris-Grignon, France. In 1991, he served as the deputy director the technical department at a corporation called SOGETA, and moved on to positions as: the Ministry of Agriculture (1994), Head of the Cereals Department at the Central Directorate of Plant Production (1995), Provincial Director of Agriculture (2005), Head of the International Cooperation Division (2007), Chief of the Cabinet of the Minister of General and Economic Affairs (also in 2007), Director of Project Management at the Agency for Agricultural Development (2009), Director-General of the Agency for Agricultural Development (2013), governor of El Jadida (2017), and interim director of ANRAC (as of September 2022). Now he’s poised to lead ANRAC into the future. Moroccan Parliament initially voted to legalize medical cannabis through Law 13-21 in 2021 legalize cannabis for industrial, medical, and cosmetic purposes. ANRAC was established in 2022 to regulate all aspects of Morocco’s cannabis industry, including cultivation, certifications/licensing, marketing, processing, and manufacturing. ANRAC held its first meeting in June 2022. By October 2022, ANRAC issued the first 10 cannabis production permits, as well as authorized companies to “market and export cannabis derivatives for pharmaceutical, medical, and industrial purposes.” In doing so, the agency allows cannabis cultivation and processing to be done through agricultural collectives. In December 2022, Moroccan law enforcement dismantled a drug trafficking operation and found more than two tons of illegal cannabis. In 2021, law enforcement seized more than 191 tons of cannabis, which reflected a decrease in seizure amounts compared to that of 2020. In March of this year, Morocco officials announced that it would begin building its first testing lab, called Bio Cannat. It was one of the 10 original businesses to receive a permit from ANRAC, according to Morocco World News. Morocco has a long-standing history of cannabis cultivation and hashish production, especially in the Moroccan Rif mountains. According to a historical study published in Cannabis and Cannabinoid Research in October 2022, entitled “Origin, Early History, Cultivation, and Characteristics of the Traditional Varieties of Moroccan Cannabis sativa L.,” it’s thought that cannabis was brought to Morocco by Arab conquerors in the 10th century. Other researchers believe that it may have been introduced by travelers going on pilgrimages to Mecca, or possibly brought by African slaves. During that time, it was likely cultivated to make food, and use for textiles and making paper. What’s more certain is that cannabis cultivation was definitely happening in the Rif mountains around the early 1800s. As of the early 1900s, cannabis was mainly used for its fibers. The study claims that European narrow-leaf hemp varieties were possibly introduced to Moroccan landrace strains. In the 1960s, it’s believed that Lebanon hashish seeds, and the process of sieving (collecting cannabis resin powder) were brought to Morocco. By the early 1980s, more Lebanese cannabis strains were introduced to Morocco. Researchers noted that these strains became less common in cultivation compared to western hybrid cultivars because they were “improved, more productive, and more potent.” Cannabis prohibition began at the end of the 19th century, when sultan Hassan I created strict laws for cannabis trade and export, although he permitted five village tribes to continue cultivating. Later on, under Spanish and French control (although mainly through a monopolized tobacco grower) until 1953. Morocco became independent in 1956, and cannabis cultivation was banned. However, those villages and mountainous cultivation areas still grew the plant. The research study notes that the Rif mountains are “unfavorable” for agriculture, due to poor soil quality and a climate that leans too hot in the summer and too wet in the winter. So cultivators are limited to growing in spring and fall. According to a recent report this summer, illegal cannabis cultivation is still common in the Rif mountains. According to the United Nations Office on Drugs and Crime, that region is one of the top producers of cannabis resin in the world today. One Moroccan cultivator, named Mourad, told Al Jazeera that he learned cultivation from friends and family, although many others learned how to grow from hippies who traveled to the mountains. However, he noted his concern for switching from illegal to legal cultivation. “Official representatives came to the village in March to discuss the new bill with us and take the names of the people who might be interested,” said Mourad. “For my part, I do not really know what I am going to do. If I am forced to switch to legal production, I will, but if most of my neighbours continue to produce cannabis illegally, I will do like them.” The Moroccan Ministry of Interior estimated in 2013 that 700,000 people rely on cannabis cultivation as their livelihood.

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From the Archives: Mr. Randall Goes to Washington (1980)

By Robert Randall Once a week I go to a pharmacy located near my home in Washington, D.C., to pick up 70 prerolled cigarettes containing two and a half ounces of marijuana. The transaction is perfectly legal. My marijuana dealer is the U.S. government. I have glaucoma, a painless, incurable eye disease. Uncontrolled, it results in blindness. In 19731 accidentally discovered that smoking marijuana significantly reduces the eye pressure associated with my disease. Armed with the medical knowledge of a tenth-grade biology student, I conducted trial-and-error tests to determine if a drug I enjoyed using could prolong my sight. By the spring of 1974 the evidence was too persuasive to ignore and I added marijuana to my complement of conventionally prescribed antiglaucoma drugs. This illicit program of medication worked reasonably well. But marijuana purchased on the black market is always expensive, often unavailable and seldom of high quality. To offset these hazards I grew my own marijuana. In August 1975 I was arrested by the District of Columbia vice squad for cultivating four marijuana plants on a secondfloor sun deck. My first impulse was to plead guilty, pay a small fine for my indiscretion and return to my career as a college professor. But within a week of my arrest I learned the federal government also knew of marijuana’s potential value in the treatment of glaucoma. Several officials actually encouraged me to continue smoking cannabis on the sly. So I freely admitted smoking marijuana but pled not guilty for reasons of medical need. To support this claim I underwent 13 days of controlled medical study in December 1975 at the Jules Stein Eye Institute at the University of California at Los Angeles. I was hospitalized for six additional days of observation in March 1976 at the Wilmer Eye Institute, John Hopkins University. Ophthalmologists at the Stein and Wilmer institutes found I was suffering a “conventional medications failure,” and submitted the same prognosis: Unable to establish adequate control over my elevated eye pressures, I would suffer a rapid progression of sight loss ending in blindness. The physicians at Wilmer proposed surgical intervention as a last resort. The research ophthalmologists at UCLA, licensed to test marijuana, recommended cannabis therapy. In May 1976 I used this information to petition federal drug-abuse agencies requesting immediate, legal access to government stocks of marijuana for medical use. Robert Rosenthal, acting chief counsel for the Drug Enforcement Administration, rejected this appeal saying, “Mr. Randall is an individual and a criminal.” He did not indicate for which of these twin sins relief was denied me. After reconsideration, the Drug Enforcement Administration decided my petition was a medical request and bucked it to the Food and Drug Administration. FDA followed DEA’s example and forwarded my appeal to the National Institute on Drug Abuse. While my petition was being dispatched into bureaucratic oblivion I went on trial in Washington, D.C., in July 1976. The pur pose of the trial was to determine if I, as an individual, were indeed “criminal.” My personal physician, Dr. Ben Fine of Washington, testified he had no firsthand knowledge of marijuana’s potential benefits (such knowledge being illegal for him to possess). He could, however, relate the primary facts of my medical history. My glaucoma was beyond the control of conventional medications; surgery presented grave risks. He concluded by telling the court, “As a physician I believe it is in the best interest of the patient to pursue avenues of possible pressure control, if they are effective, regardless of their conventionality.” Dr. Robert Hepler, then the nation’s only ophthalmologist licensed to investigate marijuana’s effect on the eye, went further. “Without marijuana he will go blind,” he told the court. “With marijuana his sight might be saved.” The U.S. attorney prosecuting me did not question the medical fact marijuana might save my sight. Nor did he bother to offer any concrete evidence to show marijuana was not safe. Instead, he.alleged marijuana could cause “(Mr. Randall’s] legs to fall off,” then added the evidence was irrelevant because there is “no constitutional right to eyesight.” After four months of deliberation Judge James Washington, Jr., ruled my use of marijuana was not criminal, but a consequence of medical “necessity” protected by law. The court declared in part, “While blindness was shown by competent medical testimony to be the otherwise inevitable result of defendant’s disease, no adverse effects from the smoking of marijuana has been demonstrated…[It] is doubtful,” the court reasoned, “that [marijuana’s] slight, speculative and undemonstrable harm could be considered more important than defendant’s right to sight.” It was the first successful case of medical “necessity” ever brought in an American court and only the 13th successful defense of necessity (a rare legal doctrine) in the 750-year history of English common law. Judge Washington’s verdict also marked the first time in 40 years that any branch of the federal government acknowledged marijuana to be a therapeutic agent. Within the month federal drug abuse agencies answered my petition by granting me legal access to government stocks of quality-controlled cannabis. I became America’s first and only legal marijuana smoker in November 1976. I smoked legal marijuana for Walter Cronkite and Tom Snyder and appeared on “To Tell the Truth.” Midnight magazine headlined, BOB SMOKES POT-AND IT’S LEGAL. The Washington Post wondered why “a man losing his sight has to rely on the courts to get the right to smoke marijuana to stave off total blindness.” Dorothy Storck, a columnist for the Philadelphia Inquirer, wrote, “One has the feeling the marijuana millennium is near.” Muckraker Jack Anderson paused between scandals to declare me “America’s most famous pot smoker,” a dubious distinction at best. I did not mind being the free world’s first legal pot smoker, but I deeply resented being the only American with medical access to marijuana. It left me feeling much like the man who makes the lifeboat and then finds he is alone. Four million Americans have glaucoma, a disease that is this nation’s second leading cause of blindness. According to the National Eye Institute 10 percent—or 400,000—of these glaucoma patients are unresponsive to conventional medications. But the question of marijuana’s medicinal use extends beyond glaucoma. Historical records and modern clinical data indicate there is a wide range of maladies that may be responsive to cannabis-based therapies. The most significant of these potentially beneficial applications for cannabis he in the plant’s ability to lower the elevated eye pressures associated with glaucoma, to reduce the nausea and vomiting generated by cancer chemotherapies and radiation treatments, and to lessen the spasticity endemic to certain types of multiple sclerosis and other neural and muscular disorders resulting in convulsion. Many patients afflicted with glaucoma, cancer and multiple sclerosis are now demanding legal access to marijuana. Growing numbers of their physicians, medical researchers and health-care professionals are also calling for marijuana’s release for medical applications, and the general public, media and politicians are increasingly supporting extensive reform measures. Recently, the National Center for Telephone Research of Pennsylvania and respected Nebraska pollster Joe B. Wilhams, found that 83 percent of the registered voters in both states approved of marijuana’s medicinal use. Farmers and ranchers in rural Nebraska were the least enthusiastic group surveyed, but by a sizable 69 percent they also supported legalizing access to cannabis for patients and physicians. On January 26, 1979, American Medical News, an American Medical Association sponsored publication distributed to physicians and health-care professionals, reported that, almost unnoticed, the question of marijuana’s legalization for therapeutic applications “is becoming one of the top medical issues this year.” The public demand for reform, while subtly expressed, has sparked a dramatic political response. In 1978, four states (New Mexico, Florida, Louisiana and Illinois) abandoned federal models of prohibition to enact laws permitting marijuana’s medical use by glaucoma and cancer patients confronting “life and sense-threatening” disability. The tempo of reform has accelerated. Fifteen additional states—Alabama, California, Colorado, Georgia, Iowa, Maine, Michigan, Nevada, North Carolina, Ohio, Oregon, Texas, Virginia, Washington and West Virginia—have enacted similar laws. Approximately 15 more states are considering measures to release marijuana for medical purposes before the end of the 1979-80 legislative session. While this mushrooming political activity is impressive, the depth of legislative support commanded by these reform actions is more instructive. The Louisiana State Senate voted 34-4 to release marijuana for medical use. In Oregon both houses of the state legislature gave unanimous consent. The conservative Florida House of Representatives approved that state’s new law by a resounding 96-6. Illinois governor James Thompson signed his state’s bill into law by calling the measure “a step forward in the practice of medicine.” Despite these innovative state laws, I still remain one of a handful of individuals with legal access to cannabis. But from my protected niche of privilege I have watched other individuals, denied similar care, suffer needlessly and go blind. Ara Cron of Wichita, Kansas, is 65, retired and suffers from glaucoma. Like many who wrote to me, Mrs. Cron wanted to know if marijuana could prolong her vision. Ara feared surgery and not without good cause. Her father had glaucoma and was blinded by ocular surgery. I could not answer her question, but instead provided her with the available research data, some general information on marijuana and the names of various federal officials. Over the next several months Mrs. Cron and her doctor contacted these officials in an effort to secure legal access to marijuana. They failed, but as a result of her efforts she attracted local press attention. Shortly after articles appeared detailing her plight she found an ounce of marijuana, a pack of cigarette rolling papers, and instructions on how to roll a joint in her mailbox. That evening Mrs. Cron’s husband, Gerald, a retired Wichita high-school principal, measured his wife’s eye pressure as he had done nightly for six years. Then Ara Cron smoked marijuana for the first time in her life. An hour later Gerald rechecked his wife’s eye pressures and found marijuana had dramatically reduced her ocular tensions. In Mrs. Cron’s case, as in mine, the reduction was significant enough to lower her pressures into the “safe” range. In the following days Mrs. Cron’s ophthalmologist conducted several informal tests and reached the same conclusion. With access to adequate supplies of quality-controlled cannabis he felt surgery might be avoided. Both he and the Crons recontacted the Food and Drug Administration, the Drug Enforcement Administration and other federal agencies to request legal supplies of marijuana. The Crons also wrote to their federal and state legislators and the Carter White House seeking assistance. They received kind responses but found no help. Within several weeks the mailbox marijuana was gone and Mrs. Cron’s eye pressure became uncontrollably elevated. Unwilling to break the law, frightened of the illegal black market, the Crons waited until they could wait no longer. By June, Mrs. Cron was forced to resort to surgery. Technically, the operation was a success. But as a consequence of surgery Ara Cron, like her father, lost most of her remaining sight. “I’m very resentful,” she told UPI months later. “There are days now I can no longer read.” The Crons do not understand why no one moved to help them. “My doctor was more than willing to treat me with marijuana in the hope surgery could be avoided or at least postponed,” Mrs. Cron explains. She sighs. “The lack of a reasonable response to his and my repeated requests for legal access to marijuana has, I feel, cost me my sight.” Ara was the first glaucoma victim I watched go blind. She has not been the last. Victims of other diseases for which marijuana offers relief have fared no better. Lynn Pierson was 25 years old and dying of cancer when I met him in December 1977. He was a tall young man who looked old beyond his years. He was bone thin and completely bald as a result of chemotherapy. The medical philosophy behind chemotherapy is both simple and savage. A patient is larger than his disease, the theory goes, so if you begin killing the patient at a cellular level, his cancer will die before he does. Chemotherapeutic agents are brutal drugs that hold out the promise of prolonged life but subject patients to violent, nearly lethal side effects. After receiving chemotherapy some cancer patients collapse or go into convulsive shock. Most suffer devastating attacks of nausea and vomit for hours or days. In some instances the trauma is so intense patients begin to vomit as soon as they enter the hospital. Lynn Pierson, like many cancer patients, received chemotherapy once, then considered abandoning the treatments, preferring death to the debilitating consequences of the cure. Fearing Lynn would abandon further treatment, his oncologist suggested he smoke marijuana to reduce the nausea and vomiting. Lynn tried marijuana, it worked, and he continued receiving his anticancer injections. “After Lynn discovered smoking marijuana made chemotherapy tolerable,” his wife Cindy explains, “he tried to get one man, a close friend, to smoke with him. The man was twice Lynn’s age and chemotherapy was killing him. But he refused to smoke marijuana, not because he doubted it worked but because it was illegal. When that man died there was just no stopping Lynn.” Pierson approached the New Mexico legislature and asked for help. His appeal received broad public support, was backed by the state’s major media, and endorsed by the New Mexico Medical Society, which called for reform. In February 1978 New Mexico adopted the nation’s first law permitting marijuana’s medical use. But repeated efforts by the state to secure “legal” marijuana from federal drug-abuse agencies proved futile. Seven months after the law’s enactment Lynn Pierson died before smoking his first legal joint or benefiting from the legislation inspired by his efforts. He was not alone. By October 1978 Dr. George Goldstein, New Mexico’s secretary for health, bluntly informed Joseph Califano, at that time secretary of the federal Department of Health, Education and Welfare, that “every patient certified by the state as eligible to receive marijuana has died before receiving the relief promised.” Goldstein put Califano on notice that “further delays on the part of FDA are neither morally nor ethically defensible.” In a Health Department report issued in January 1979 New Mexico’s chief of substance abuse, Dr. Edward Deaux, complained that “it was definitely the intent of the [state law] to establish a program through which glaucoma patients and cancer chemotherapy patients could receive marijuana. Not to establish a program to deceive these patients into believing that they were receiving marijuana when, for the purposes of satisfying federal requirements, many were not.” Upon receiving the report, the New Mexico legislature reaffirmed the state’s decision to create legal, medical channels of access to marijuana and renamed the law in honor of Lynn Pierson. While public attention is beginning to focus on the question of marijuana’s use in the treatment of glaucoma and as an adjunct to chemotherapy, patients with less dramatic but equally sinister maladies are also unable to obtain relief. Meredith S. is a stunningly beautiful young woman who appears vital and filled with life. But like a million other Americans Meredith is afflicted with the spasticity that is frequently the result of multiple sclerosis. Like glaucoma and cancer, multiple sclerosis is incurable and the available medical treatments are limited. Multiple sclerosis disrupts nerve tissue and impairs the transmission of messages to and from the brain. It eventually cripples an individual by inflicting accumulative damage to the nerves. Introduced to Meredith through a mutual friend, I was skeptical when she told me she smoked marijuana to calm the spasticity caused by her disease. “Without marijuana I was in and out of the hospital every six months, growing weaker with each attack,” she said. “But if I smoke marijuana when I feel an attack coming on, I’m able to relax until it subsides.” Current therapies for multiple sclerosis involve the use of sedating, tranquilizing and narcotic substances, many of which are highly addictive and impair a patient’s ability to function normally. Meredith’s physicians knew she smoked marijuana and did not object. “Since I started smoking marijuana,” she told me, “I’ve learned to ski. Two or three nights a week I go dancing. Those are things I never thought I’d be able to do.” Marijuana was once prescribed as an antispasmodic, but there was no modern data on the subject when I spoke to Meredith in early 1977. Yet within a month of speaking with Meredith, I received letters from three other multiple sclerosis patients who made precisely the same claims. After months of appealing to the government for help Meredith found it easier to buy marijuana illegally. Early in 1979 the first study evaluating marijuana’s utility in the treatment of multiple sclerosis was published. Seven out of nine patients given marijuana experienced a reduction in spasticity. Dr. Tod Mikuriya, one of the nation’s pioneers in the field of marijuana research, is one of the most articulate critics of present policies. In Marijuana Medical Papers, a book devoted to cannabis’s therapeutic use, published in 1973, Mikuriya charged, “Medicine in the Western World has forgotten almost all it once knew about the therapeutic properties of cannabis. The treatment of a disease is far more important than the irrational prohibitory law which forbids marijuana’s medical use.” In Mikuriya’s mind, our present problems stem from “the illegitimate removal of cannabis from medical use in 1937, and a continuing attempt by federal agencies to rewrite history by seeking to create the impression marijuana is a ‘new’ drug.” Until the introduction of morphine, marijuana was the major painkilling drug used by the Union soldiers during the Civil War. Marijuana was available by prescription in this country for nearly a century. Between 1850 and 1940, several hundred articles extolling cannabis’s healing properties appeared in reputable medical journals. As late as 1924, the Merck Manual, a popular health guide, advised the use of marijuana for conditions including “eyestrain, nausea, vomiting, digestive distress and convulsive disorders.” During this same period almost no public concern was expressed about recreational use. The Reader’s Guide to Periodical Literature, a fair measure of cultural concerns, lists no articles on cannabis between 1917 and June 1935. In 1937, however, the Federal Bureau of Narcotics encouraged Congress to enact a prohibition against marijuana’s social use. Coincidentally, Harry Anslinger, the bureau’s director, published a book titled Marijuana: The Füller Weed. Borrowing from the popular detective fiction of this period, Anslinger’s book was laced with descriptive gore ranging from rape to murder. And it was effective. The Reader’s Guide to Periodical Literature for 1937-1939 boasts more than a dozen articles condemning marijuana’s social use. This sudden, well-cultivated surge in public concern over marijuana’s potential, if unproven harms galvanized Congress. Legislation outlawing the drug’s use was drafted. The only organized resistance against the prohibition came from the medical profession. Dr. William Woodward, a lawyer-physician and the American Medical Association’s Washington lobbyist, strongly opposed legislative action. In testimony before Congress, Woodward raised two objections to the proposed prohibition. First, he argued, marijuana was not dangerous enough to warrant legal sanctions against its social use. Second, and more particular to his professional interests, Woodward told Congress that efforts to enforce a social prohibition would result in a federal regulatory scheme that would interfere with marijuana’s legitimate use and thwart scientific study into the plant’s beneficial applications. “In all you have heard thus far,” Woodward said, “no mention has been made of any excessive use of the drug by any doctor or of its excessive distribution by any pharmacist…To say, however, as has been proposed here, that the use of the drug should be prevented by a prohibitive tax, loses sight of the fact that there are substantial medical uses for cannabis.” Congress dismissed Woodward’s medical judgment and passed the Marijuana Tax Act of 1937. Though the act did not specifically prohibit marijuana’s medical use, Woodward’s fears were quickly realized. By 1938, the Federal Bureau of Narcotics had promulgated 60 pages of additional regulations covering marijuana’s use in medicine. Ostensibly, these regulations sought to discourage the diversion of medicinal cannabis into social uses. Whatever the rationale, these federally imposed controls abruptly ended marijuana’s medical use in America. Major pharmaceutical companies, including Upjohn, Eli Lilly and Sharp & Dome, abandoned promising research programs. By 1941, marijuana and 28 cannabis-based extracts were dropped from the Pharmacopoeia of the United States (a list of available medicants) after a century of accepted medical use. With the medical profession effectively neutralized, the Federal Bureau of Narcotics, a police agency of the Treasury Department, assumed absolute control of all cannabis-related study. Between 1937 and 1967 the only extensive, long-term studies of marijuana conducted in the United States were undertaken by U.S. intelligence agencies, notably the Office of Strategic Studies (OSS) and the Central Intelligence Agency, in their search for a mind-control drug. This valuable store of data on marijuana and specially prepared cannabis extracts was destroyed in 1973 when retiring CIA director Richard Helms ordered all mindcontrol files shredded. Of course, the federal government’s ironclad control over marijuana’s availability for medical study did nothing to discourage the drug’s social use. By the mid 1960s, millions of white, middle-class youths were turning on. Citing these patterns of accelerating social use, Pres. Richard Nixon called for an even more comprehensive system of federal controls. His vehicle was the Uniform Controlled Dangerous Substances Act, drafted in 1970, a year after the Supreme Court ruled the Marijuana Tax Act of 1937 was unconstitutional because it was based on double jeopardy. The Controlled Substances Act creates five distinct classes or schedules of regulation. Marijuana was placed on Schedule I, the most restrictive classification possible, along with drugs such as heroin and LSD-25. Schedule I substances, legally defined as “without accepted medical value,’’ are said to have a “high potential for abuse.” As such, the medical use of Schedule I drugs is forbidden. Research on cannabis is possible, but only after such study has been subjected to review and approval by federal drug-abuse agencies. The Drug Enforcement Administration, a progeny of the Federal Bureau of Narcotics and a police agency of the Department of Justice, administers the Controlled Substances Act. The FDA has the authority to determine a drug’s classification and the DEA enforces the determination through the power of arrest. Charged with regulating the security that surrounds Schedule I substances, the DEA can veto any program of cannabis study it deems “inappropriate.” To make marijuana available for officially sanctioned research while respecting Schedule I prohibitions against the plant’s therapeutic use, the FDA has declared marijuana a new drug. As a new drug marijuana is regulated under the Food, Drug and Cosmetics Act and researchers must comply with the agency’s complex Investigational New Drug (IND) procedures. Through the IND process, the FDA has the power to accept or reject, advance, delay, adjust or amend any proposed program of study involving marijuana. A third federal agency, the National Institute on Drug Abuse (NIDA), enjoys an exclusive monopoly over the legal cultivation of marijuana in the United States. NIDA functions as the federal government’s marijuana drugstore, and manages federal funds available for the study of drug abuse. By exercising its dual authority over marijuana supplies and research funds, NIDA has a direct influence on the design and direction of marijuana’s evaluation. Thus, to obtain access to federal stocks of cannabis, a licensed physician (or a state] must request and receive supplies of marijuana from NIDA, comply with FDA procedures and satisfy DEA Schedule I security requirements. In the past decade the federal government has spent more than $40 million on marijuana-related research. Yet less than $1 million has gone into the exploration of the potentially beneficial applications of cannabis. The vast bulk of funds and research has gone instead into a deliberate effort to scientifically and medically demonstrate that marijuana is a drug of abuse. Under the Food, Drug and Cosmetics Act, only two essential criteria qualify a substance as a medicine: First, it must be “safe” relative to the disease being treated; second, it must be “effective” in providing patients relief. Since 1970 federal drug-abuse agencies have been aware of marijuana’s potential use in the treatment of glaucoma. In that year researchers at UCLA accidentally discovered that cannabis lowered eye pressure. By September 1971 Dr. Robert Hepler communicated an outline of the UCLA findings to the Journal of the American Medical Association. Hepler wrote, “The purpose of this letter is to present preliminary data concerning the most impressive changes observed so far, namely, a substantial decrease in intraocular pressure [following the use of marijuana]. The possible implications,” he stressed, “including … therapeutic action in the treatment of glaucoma are obvious.” While Hepler continued his work without funds, other short-term studies, some unauthorized, rechecked his findings and reached the same conclusion. By 1975 Hepler informed NIDA that “marijuana produces a consistent, dose-related, clinically significant reduction in intraocular pressure.” University of Georgia at Athens researcher Dr. Keith Green, approaching the question from a different perspective, reached the same conclusion. In 1976 Green told reporters, “Marijuana is as good as, if not better than, any existing glaucoma-control drug.” The federal response to these important medical discoveries was nonexistent. Even my court victory demonstrating marijuana’s potential value in the treatment of glaucoma in 1976 failed to ignite interest. NIDA, for example, funded no glaucoma-related research in 1976, 1977 or 1978. In late 1978, the National Eye Institution (NEI) publicly announced it would fund study in this area. At present NEI tells reporters there are five federally approved programs of study. NEI fails to point out that none of these programs is funded and that three are in various stages of suspension. My private program of medical care and a second single patient constitute the remaining two studies reported by NEI. Thus, a decade after Dr. Robert Hepler discovered the link between cannabis and reduced intraocular pressure, only two glaucoma patients in the United States are legally receiving marijuana. This same pattern of neglect toward marijuana’s medical use is not confined to glaucoma, but extends across a wide range of inquiry. Dr. Norman Zinberg and Dr. Stephen Sallan, of Harvard University and the Sidney Fabrer Cancer Center respectively, became intrigued when cancer patients who smoked marijuana reported less nausea and vomiting following chemotherapy. Working without funds they clinically analyzed these “anecdotal accounts” and found marijuana was an effective antiemetic. Moreover, Zinberg and Sallan learned what to most social marijuana smokers is obvious: Marijuana stimulates the appetite. Cancer patients who smoked marijuana got the “munchies,” ate well and maintained their weight during chemotherapy. By 1975, Zinberg and Sallan reported their findings to the New England Journal of Medicine. Sallan, who has continued his research, says, “To have less anxiety, little vomiting and a better appetite takes care of many of the toxic side effects of chemotherapy.” Ann Guttentag, a 53-year-old Pennsylvania cancer patient, agrees. “Without marijuana I doubt I would have made it this far.” Mrs. Guttentag calls Compazine, the antiemetic her physician prescribed, “a real dud. It made me feel dopey and didn’t work. I would vomit for hours. But with marijuana I just take a few puffs and the nausea and vomiting goes away. My appetite returns and I raid the refrigerator.” With the help of her doctor Mrs. Guttentag is now seeking federal permission to smoke marijuana legally. “I just don’t like getting my medicine off the streets,” she says. Physicians whose patients smoke marijuana face a compromising dilemma. A Washington, D.C, oncologist who asked not to be identified laments, “What am I supposed to do? Call the cops? Tell my patients to stop smoking? Not when the patients know marijuana works and they know that I know it works. I tell them to keep puffing. I’m a doctor, not a policeman.” With all the evidence, both clinical and anecdotal, from cancer and glaucoma patients and their physicians demonstrating marijuana’s medical value, why is cannabis being denied to those who might benefit? The Drug Enforcement Administration argues it is a police agency, not a medical clearinghouse. The Food and Drug Administration describes its role as “passive” and notes it has no funds to pursue marijuana’s medical use. The National Institute on Drug Abuse says its responsibilities are limited to evaluating a drug’s “abuse potential,” not its therapeutic value. Dr. Sidney Cohen, a longtime investigator of illicit drugs, told Psychology Today in 1978, “It is not necessary to be a masochist to study marijuana, but it certainly helps.” Cohen then Used 11 federal and state agencies involved in certifying, licensing, supplying and approving his marijuana-related research. Another physician familiar with this intimidating, multibureaucratic system of controls came away with “a gut feeling the federal government does not want anything positive to come out on marijuana.” This same system of regulatory disincentives is now being deployed against those states that have legalized marijuana’s therapeutic use. Last December, Barbara Weiner, an official of the Illinois Dangerous Drug Commission, complained, “The federal government is speaking with so many different, often conflicting voices, it is nearly impossible for the states to divine an appropriate remedy.” Even if the states penetrate these regulatory barriers, their efforts may prove futile. Since 1976 the quality and quantity of federal supplies of marijuana have declined dramatically. Indeed, NIDA has so mismanaged the nation’s only legal marijuana drugstore that the federal cupboard is bare. By conservative estimate 1.5 to 2 million glaucoma and cancer patients reside in the 20 states that have already recognized marijuana’s medical value. Even under the most restrictive programs of access, 150,000 to 400,000 individuals are legally qualified to receive access to marijuana. Yet in the face of rapidly accelerating demands and despite dire warning of an impending supply crisis, NIDA actually reduced the size of the 1979 crop to a mere three acres. Federal officials continue to reassure the states that supplies are adequate to meet “any conceivable need.” But by mid 1979 the supply shortage was so acute that Dr. Seymor Perry, chairman of a Carter-appointed interagency committee, admitted that NIDA could meet the medical needs of fewer than 250 individuals. NIDA is now offering the states a consolation prize: a synthetic marijuana substitute called delta-9 THC. Despite the fact that THC is more psychoactive than real marijuana and medically inferior in terms of the relief it provides, NIDA is aggressively pushing THC. A “pot pill,” even if ineffective, is more bureaucratically pleasing than having to admit that real marijuana has real medical value. Several states, sensing these trends, have sought to avoid the red-tape runaround. If NIDA fails to make good on its promise of adequate supplies both Iowa and Michigan have threatened to use confiscated (state-owned) marijuana. Oregon may abandon federal control completely and establish an intrastate program of cultivation and distribution. Washington will not look kindly on such innovative approaches. Control over supplies of marijuana is the last means by which federal agencies can manipulate the issue and the legality of intrastate solutions is uncertain. Indeed, only one thing seems certain: Patients, promised medical access to marijuana under state laws, are being deprived of marijuana by an entrenched federal bureaucracy terrified by the prospects of change. Unable to obtain marijuana legally, seriously ill patients are resorting to the illegal, unregulated black market for relief. According to American Medical News, “thousands—and perhaps tens of thousands—of glaucoma and cancer patients across the country” are medicating themselves with marijuana. As bureaucrats bicker and interagency committees meet patients, physicians and health-care professionals are stumbling through a legal no-man’s-land, making do with what is available. Should marijuana be released for medical applications? To thousands of patients, their families and physicians, this is like asking if the pope is Polish. The federal government may pretend marijuana is as mysterious as the planet Mars, but marijuana’s ability to reduce intraocular pressure, reduce the nausea and vomiting associated with chemotherapy, and control the spasticity generated by certain types of multiple sclerosis is obvious to many patients without a day of medical training. As long as the federal government retards research it can inversely argue there is not enough data to reach a conclusion. As long as “anecdotal accounts” are greeted with the same neglect given “folk medicine” (that vast 5,000-year period immediately preceding the Marijuana Tax Act in 1937), the prohibition will remain in force. Two generations—four decades—of Americans have already suffered unnecessary pain or blindness due to federal interference in marijuana’s medical evaluation. Perhaps it is time to consider a fresh approach. The state laws now being enacted beckon toward a more reasonable and responsible policy. But these actions will remain unfulfilled gestures until substantive reform occurs in Washington and in the philosophies of abuse that dominate bureaucratic interests. Until congressional action revamps existing policies, bureaucratic assumptions centering on marijuana’s social use will continue to condemn seriously ill citizens to a choice between unnecessary physical injury and violating the law. This choice, really no choice at all, has been made. Patients are smoking marijuana. The only question is When will they be allowed to buy medication in pharmacies instead of on the streets?

https://hightimes.com/

Coffee, Cannabis & Color in Colombia

Ignoring warnings from my family and that internal fear monster informed by nothing more than movies about narcotraficantes, I board the plane for an adventure in Colombia. From the moment I see Santi’s welcoming smile as I wheel out of the baggage area, I feel my anxiety dissipating. This is going to be an amazing weekend with Wind Hill Tours, the brainchild of Damian Holman, a cannabis grower based out of Maine. He, his wife Sonja, and their business partner Santi have brought down two other “cannabis influencers” (Mary Pryor and Ace King) to assess the tour and to advise how to make the experience as amazing as possible. Scooping our baggage, Damian drives us out to Finca El Huerto. As we pull up, I look through the open air foyer and directly out to the Andes Mountains. My mouth drops open as I walk onto the splayed-out ranch estate. Bougainvillea and other flowering trees and shrubs form a semicircle around the infinity pool. The rooms of the house encircle the trees and I instantly feel wrapped in a cocoon of nature’s luxury. We relax, smoke some provided pre-rolls, and chat as the chefs prepare our first dinner. Damon tells me his vision for Wind Hill Tours as the first all-inclusive resort experience focused on wellness through the lens of cannabis. I advise him that he will be able to provide the best possible experience for his guests once his own cannabis grow is established. There is nothing like providing single-source quality as flower or hash. Though the industry is nascent—personal consumption in Colombia is decriminalized and a proposal to legalize cannabis for adults is currently in motion at the time of my visit in fall 2022—there are no growing conditions quite like those found in Colombia with its fertile volcanic soil and consistent 12/12 photoperiod. I open the pre-rolls and reroll them with rosin smeared on the paper. That’s better. At the crack of dawn the next day, I throw on a light hoodie, grab my already packed chillum, and pad out to the pool. I appreciate the lightly scented breeze that whispers through the valley songs of contentment. Facing out to the Maravelez Valley, I take a deep hit and surrender to the thick smoke which overtakes my airway, charges down into my lungs and blossoms into a pleasant warmth before sliding back through my lips. Almost immediately I feel tension releasing from my face. I had slept very well, but sometimes I need THC-laden moments like this to truly let go. The sun has just begun banishing the thick fog that had been blanketing the mountains when I finish the last of my chillum. I knock it firmly into my palm and allow the ashes to fall down before disappearing in the fragrant wind. Our first stop is a coffee finca, La Pradera. We start on a small hike to the property, crossing bamboo bridges over rushing creeks, wild coffee bushes crowding the path, and other tropical flora. Santi gives us the coffee tour, plucking unripe, yet still potent, berries for our sweet sucking pleasure. Upstairs at the coffee terrace, we sip perfectly prepared coffee, appreciate the mountains, and enjoy the sweet sounds of salsa and merengue. Newly charged with caffeine we head over to the cannabis farm, IQ&A. We are warmly welcomed and sensing our haste, the team hustles us into blue scrubs and head coverings before ushering us into the greenhouse. My face alights with joy seeing these wonderfully healthy plants. Although each household in Colombia can grow up to 20 THC plants, this legal grow is strictly CBD. We sashay through the rows; admiring the bountiful life and delight in the various terpene rich varieties. The grow is as impressive as any in California’s Emerald Triangle. We finish off the tour in a lofty perch, smoking chillum and talking about the amazing view of the Andes. Sunday morning finds me laying by the pool and puffing flower and rosin in my chillum before it is time for yoga with Jimy Betancurt. I slide through the poses with ease as I am in the zone; uncaring of any of life’s trivialities. Jimy assures us that with proper breathing and technique, we can achieve the same state of oneness and stillness that we get from our cannabis. I believe him, but I take another puff just in case. A few hours later, we pass around joints of Cholado, Bubblegum, and Bubba Kush as we head for Salento, a small town known for its wild color; as if some larger than life artist had selected all of the doors, shutters, tiles, and window sills, and splashed every surface with a different hue. We traipse through the town and up 242 stairs directly to the Alto de La Cruz lookout which gives us the best view of the town. The combination of the glaring pigments, the sun beating from above, and the effects of several joints has my head swimming in surreal, slightly off kilter awe. After a much-needed lunch, and under a persistent mist, we make our way to the nearby Valle de Corcora. We are looking to see the tallest wax palms in the world. As the Jeep barrels steadily down the road, trees and grasses sporting the most verdant leaves reach out to further entice our senses. Between the grand flora, we get glimpses of wild horses running with wild abandon; oblivious to our wide eyed stares. A few waterfalls punctuate the grand landscape. We arrive at the valley under relentless rain and I look at the proposed hiking path dubiously as the sodden ground squelches with every step. I awkwardly slip and slide my way over the fairly steep course and just when I am exhausted from the thigh workout (and mentally pooped from the lack of THC), I see the turnaround for the loop. It is a beautiful overlook of the valley and the wax palms, some of them 200 feet tall, stand erectly and in complete defiance of gravity. We have been advised not to fly the drone, but the view is just too tempting. Truthfully I too am ready to throw care to the wind and I take out a vape pen to replenish my endocannabinoid system. I plop down at the feet of a statue of Groot and I shake my head in wonder at all of the lusciousness of this whole endeavor. Colombia has been good. This adventure has been a heady expression of nature’s beauty and bounty. As THC has coursed through my body, my mind has soared wildly; buoyed not only by the cannabinoids, but also the sense of wonderment as Colombia reveals its next fascination. I have spent my time in Colombia reveling in the psychedelic experience of smelling, tasting, hearing, feeling, and seeing everything in a larger than life way. In one weekend, Wind Hill Tours has made considerable strides in its mission to provide a safe oasis for personal rejuvenation through cannabis and immersion in nature, as well as contribute to a new narrative of all that Colombia can be. This article was originally published in the March 2023 issue of High Times Magazine.

https://hightimes.com/

Rough Riders: 6 Positive Takeaways from Legalization

I’d like to start with the acknowledgement of everything good that’s happened during this decade-long royal ball sideshow. Whether we want to acknowledge the degree of foolishness and the feeling of lost years due to spinning, what we can’t forget is what went right.  Number 1: We can mostly talk about weed anywhere now.  The exclusivity of acting as a dark agent to the status quo has definitely been reduced. That was fun and is missed. More so with weed, because it has some benefits and a nonexistent direct body count. Anyone that has danced with the sale of substances that fully enslave people by effect, have inevitably, at least once or twice acted as a precursor to the hooded spirit with a scythe. There’s a cost when your game currency consists of drugs that make the soul easy to slaughter. This is a rare situation with cannabis users. Most cannabis mortalities seemed to be ‘wrong place, wrong time’ incidents. Some cannabis user low moments can be attributed to mental illness. This should be expected, look at the atomic cocktail the human race has become and the strange layers of past eras we have built a world upon.  Even with the full reality in scope, I think it’s safe to say, sugar has enslaved and destroyed more lives than cannabis, at least in this country. Number 2: The start of the industry brought in a lot of action. One of the results of the war on drugs is that beneficial or medical psychoactive plants were traded adjacent and within the economy of all things not allowed. A tenuous and stressed economic system but one that provided a way for a few to level up out of poverty or a lifeless middle class. An economic system with a high body count. That economy has enticed the lower echelon of first round investors for the state legalization efforts. Those who were willing to risk a lot. Most used the chaos to fleece millions from family offices, shareholders, or private money. Some wanted to be that guy in that movie they watched while hoovering through an eight ball and some just thought it was cool to be a part of bringing cannabis lawfully into the market. I’ve worked with a few of the latter. Good to see them but also sad to see them lose ambition as the layers of scummy rules and people wore on their net worth. Some are still here, stuck with too much in, grimace riding their way through it, sometimes with the help of the mortal drugs available on the market of all things not allowed. Regardless, a solid few made off with a few lifetimes of cash and a lot of us made a living. Number 3: Plant breeding and new strains have steered the market. This is largely due to a few brands that understood how aromatic associations with foods and candies and a terpy weed analogue could be packaged in a way that psychologically related cannabis with items in the pantry. Innocuous cartoon baked goods and candy boxes on shorts, hoodies, and backpacks splattered their way around the common city square. It worked so well even backpacks with cartoon images of backpacks that would theoretically hold the pastry comic art flowered filled mylars became a thing. This pantry trend did bottleneck a lot of the wide genetic expressions available for consumption but that is starting to shift as more markets with different smoker cultures continue to pop up from legal states coming online. The value of unique varieties is established and has become a path for growers, breeders, or selectors to create a place in the market no matter their footprint. It’s a lottery with popping seeds but there are more winners with cannabis than any other gamble if you can read the current room and predict the coming trends. Number 4: Good smoke is available to all more than ever. There is still a lot of bad flower and products, but it’s easier now than ever to find amazing flower and hash. The cannabis economy does prefer cost still over quality. People have less money, so getting passable flower for a low cost has now become the preference for most. This has also led to more people growing their own and learning the plant craft. Oregon, the barren wasteland for the small and medium sized business who were decimated with oversupply and a hemp rush that was mostly cloaked real weed farms is now left with numerous small growers, seed makers and plant selectors doing their thing carving out small customer bases while working other jobs. Not ideal if you want cannabis to be your only source of bacon, but it is something. A lot of us in California look north to Oregon, praying that this isn’t our fate but witnessing a lot of the same signs. Maybe the only hold out is that California has been a nucleus for good weed and novel genetics. It still is, but that will only hold up as long as California holds up as a myth machine for new trends. At the moment, the allure of the west coast seems to be fading even if most of the world still perceive it as the “home of the best weed”. Still amazing cultivators and plant makers still live here and as long as they keep participating and bringing new things to the market, us Californians, have a chance to ride another wave. Number 5: Even law enforcement is lobbying for federally legal weed. And they are growing and selling it as well. Which is where it gets a little sticky. If you weren’t growing during the medical era of proposition 215 in California, you might not be aware that law enforcement’s position on both sides of the fence was strong prior to recreational licensing. So this is nothing new. What is new is that we can talk about it. Prior if you were raided, caught a charge and won the case only to find that a portion or none at all of your confiscated cannabis products were returned to you would raise an eyebrow but you wouldn’t ask where it went. It should be no surprise that during this time many law enforcement officials allegedly would have side hustles with medical dispensaries moving confiscated products into the market under protected shops receiving a profit from the sales. It is a strange rub seeing former law enforcement on culturally relevant weed podcasts touting themselves as leaders in the legalization movement appropriating advocacy movements and tokenizing a few supposed victims of the war on drugs while leveraging a publicly traded company into the largest seat at the table. It feels like a Black Mirror episode. It accurately feels like modern America. A cascading of past, present and future narratives cased into a feel good virtue soapbox with a massive profit potential but the box is empty. There isn’t enough bleach, soap or cleanser that can wash away the long standing impact of doublespeak propaganda that has petrified like diseased mind particles from the era of prohibition and its beneficiary, law enforcement and big business. If former law enforcement wants to stick it to the war on drugs, it would feel virtuous only if there wasn’t a carrot hanging on their stick, but I am not sure that those from that culture have ever known a carrot without a stick. Clearly, the virtuous path here is to fight for change around cannabis without a profit motive. Fight for it to change, because it is the right thing to do. Fighting for it to change because you know at some point you’ll be able to sell your weed company to big pharma for a billion dollars is not virtuous, it’s more of the same.  Number 6: Cannabis legalization began during the golden age of social media, creating a platform for normalizing its use to the world. Social media has without a doubt made and broken many in the cannabis space. Mid 2010s it was a virtual Mecca for trends, genetics and determining market value for specific growers and strains. If you were able to launch a brand and sell it prior to 2019, there is little doubt that you have won some sort of success in this space. Post-pandemic, social media’s use has been weaponized more as businesses, partnerships and markets have faltered. As the algorithms elevate the more contentious content and more contentious scenarios played out with the bubble beginning to implode, social media around the cannabis industry is feeling more like a carbon fiber plated tube thousands of feet below its operating depth on a mission to view the sunken ship of a industry that could have been, only to implode before viewing the wreckage. Instead, many with some harboring resentments towards the current state get high by hiding behind anonymous accounts and picking apart with perverse humor the failed state still dressed up like a lipstick smattered pig. It wouldn’t be honest if I didn’t admit that my participation in this trend has been less than superfluous. I understand fully the small wins of highlighting the skullduggery with a post that warrants a painful laugh. I also know that posting a weed pic just gets you in trouble and as much as I would prefer to post cannabis pics, the drama always brings more conversation and engagement. It becomes a hard pinning role and leaves little room for mobility out of that position and the cost of cashing in for the engagement by low key trauma posting through targeting memes can limit how and who you will work with in the future. People just trucking through the noise with a ten year plan have little time to even look at the drama, but we cannot argue that social media is an effective weapon. I am just not sure that any of us have really earned the power to wield it and are free enough from our own bullshit to be the moral adjudicator of the cannabis space. This includes myself. Most here will just hustle that engagement for a profit, and in the end aren’t too far from the true intentions of law enforcement carrying on with a publicly traded weed company spouting cheap virtue aphorisms on justice. It’s really just a lot of spin encased in a virtual drug. Meanwhile the rappers and duffle bag boys keep grifting away to consumers who just want cheap or hype weed, never to be accepted by their peers who know and have felt their unscrupulous behavior, but without a doubt are still catching the bag for how much longer, I do not know. In any event, troll trauma posting is getting old and it’s time to start developing a new form of market creation and competition. These social low points are always the womb for new waves of creativity. Just make sure that you vet your corporate sponsors. This last point I know is a hard ask. There is much that is not functioning and when the losses keep stacking up an easy win is there with some online character assassination. My argument is that this trend will also lose its relationship with reality, where drama will be engineered to drive engagement. Trolling for some sort of change or awareness will just end up as a marketing strategy solely. Losing its power, like most things do, into the void of short term profitability. The muddy banks of an emerging industry held like a social experiment by the federal government, measuring whether they open up the market through descheduling or limiting its legal expansion by rescheduling within the world of big tobacco and pharmaceuticals, will use what we have created as a reference point for that decision. We still live under a master and they continue to act as one as long as we continue to buy what they sell. Right now, biotech companies and private equity are investing heavily in low THC genetically modified cannabis plants as a substitute for tobacco. I’m not sure how that will work, since nicotine is a far different stimulant and its legal yet regulated proliferation has almost fully negated the awareness and intentional use of its neurotrophic medical benefits that could be used in substitution of antidepressants and SSRIs. Like tobacco, will we lose the purposeful use of cannabis and its medical benefits while these Optimus Prime level industry actors descend into the chaos of the current state? I think it’s likely as more and more of reality continues to play out like the Twilight Zone. We can still resist this by continuing to organize into small thoughtful online groups, perhaps trolling more the meta than the individuals, unless of course the meta becomes an individual. A larger than life icon with the power to determine the industry trajectory as a whole, conspicuously breaking all the rules and continuing to get a pass from the powers that be. Those entities, icons, or organizations, should continue to be tested. As any power should be that could shape the future of our collective and individual dreams. They determine who or who doesn’t sit at the table, and that is also a power that is too great for one or a few, because in the end that power rules over them more than they rule over anything else, bringing forth a primal state of behavior. Behaviors that bury its passengers leagues under a weighted sea, shoddily wrapped in a glossy material that screams hubris.

https://hightimes.com/

Rough Riders

I’d like to start with the acknowledgement of everything good that’s happened during this decade-long royal ball sideshow. Whether we want to acknowledge the degree of foolishness and the feeling of lost years due to spinning, what we can’t forget is what went right.  Number 1: We can mostly talk about weed anywhere now.  The exclusivity of acting as a dark agent to the status quo has definitely been reduced. That was fun and is missed. More so with weed, because it has some benefits and a nonexistent direct body count. Anyone that has danced with the sale of substances that fully enslave people by effect, have inevitably, at least once or twice acted as a precursor to the hooded spirit with a scythe. There’s a cost when your game currency consists of drugs that make the soul easy to slaughter. This is a rare situation with cannabis users. Most cannabis mortalities seemed to be ‘wrong place, wrong time’ incidents. Some cannabis user low moments can be attributed to mental illness. This should be expected, look at the atomic cocktail the human race has become and the strange layers of past eras we have built a world upon.  Even with the full reality in scope, I think it’s safe to say, sugar has enslaved and destroyed more lives than cannabis, at least in this country. Number 2: The start of the industry brought in a lot of action. One of the results of the war on drugs is that beneficial or medical psychoactive plants were traded adjacent and within the economy of all things not allowed. A tenuous and stressed economic system but one that provided a way for a few to level up out of poverty or a lifeless middle class. An economic system with a high body count. That economy has enticed the lower echelon of first round investors for the state legalization efforts. Those who were willing to risk a lot. Most used the chaos to fleece millions from family offices, shareholders, or private money. Some wanted to be that guy in that movie they watched while hoovering through an eight ball and some just thought it was cool to be a part of bringing cannabis lawfully into the market. I’ve worked with a few of the latter. Good to see them but also sad to see them lose ambition as the layers of scummy rules and people wore on their net worth. Some are still here, stuck with too much in, grimace riding their way through it, sometimes with the help of the mortal drugs available on the market of all things not allowed. Regardless, a solid few made off with a few lifetimes of cash and a lot of us made a living. Number 3: Plant breeding and new strains have steered the market. This is largely due to a few brands that understood how aromatic associations with foods and candies and a terpy weed analogue could be packaged in a way that psychologically related cannabis with items in the pantry. Innocuous cartoon baked goods and candy boxes on shorts, hoodies, and backpacks splattered their way around the common city square. It worked so well even backpacks with cartoon images of backpacks that would theoretically hold the pastry comic art flowered filled mylars became a thing. This pantry trend did bottleneck a lot of the wide genetic expressions available for consumption but that is starting to shift as more markets with different smoker cultures continue to pop up from legal states coming online. The value of unique varieties is established and has become a path for growers, breeders, or selectors to create a place in the market no matter their footprint. It’s a lottery with popping seeds but there are more winners with cannabis than any other gamble if you can read the current room and predict the coming trends. Number 4: Good smoke is available to all more than ever. There is still a lot of bad flower and products, but it’s easier now than ever to find amazing flower and hash. The cannabis economy does prefer cost still over quality. People have less money, so getting passable flower for a low cost has now become the preference for most. This has also led to more people growing their own and learning the plant craft. Oregon, the barren wasteland for the small and medium sized business who were decimated with oversupply and a hemp rush that was mostly cloaked real weed farms is now left with numerous small growers, seed makers and plant selectors doing their thing carving out small customer bases while working other jobs. Not ideal if you want cannabis to be your only source of bacon, but it is something. A lot of us in California look north to Oregon, praying that this isn’t our fate but witnessing a lot of the same signs. Maybe the only hold out is that California has been a nucleus for good weed and novel genetics. It still is, but that will only hold up as long as California holds up as a myth machine for new trends. At the moment, the allure of the west coast seems to be fading even if most of the world still perceive it as the “home of the best weed”. Still amazing cultivators and plant makers still live here and as long as they keep participating and bringing new things to the market, us Californians, have a chance to ride another wave. Number 5: Even law enforcement is lobbying for federally legal weed. And they are growing and selling it as well. Which is where it gets a little sticky. If you weren’t growing during the medical era of proposition 215 in California, you might not be aware that law enforcement’s position on both sides of the fence was strong prior to recreational licensing. So this is nothing new. What is new is that we can talk about it. Prior if you were raided, caught a charge and won the case only to find that a portion or none at all of your confiscated cannabis products were returned to you would raise an eyebrow but you wouldn’t ask where it went. It should be no surprise that during this time many law enforcement officials allegedly would have side hustles with medical dispensaries moving confiscated products into the market under protected shops receiving a profit from the sales. It is a strange rub seeing former law enforcement on culturally relevant weed podcasts touting themselves as leaders in the legalization movement appropriating advocacy movements and tokenizing a few supposed victims of the war on drugs while leveraging a publicly traded company into the largest seat at the table. It feels like a Black Mirror episode. It accurately feels like modern America. A cascading of past, present and future narratives cased into a feel good virtue soapbox with a massive profit potential but the box is empty. There isn’t enough bleach, soap or cleanser that can wash away the long standing impact of doublespeak propaganda that has petrified like diseased mind particles from the era of prohibition and its beneficiary, law enforcement and big business. If former law enforcement wants to stick it to the war on drugs, it would feel virtuous only if there wasn’t a carrot hanging on their stick, but I am not sure that those from that culture have ever known a carrot without a stick. Clearly, the virtuous path here is to fight for change around cannabis without a profit motive. Fight for it to change, because it is the right thing to do. Fighting for it to change because you know at some point you’ll be able to sell your weed company to big pharma for a billion dollars is not virtuous, it’s more of the same.  Number 6: Cannabis legalization began during the golden age of social media, creating a platform for normalizing its use to the world. Social media has without a doubt made and broken many in the cannabis space. Mid 2010s it was a virtual Mecca for trends, genetics and determining market value for specific growers and strains. If you were able to launch a brand and sell it prior to 2019, there is little doubt that you have won some sort of success in this space. Post-pandemic, social media’s use has been weaponized more as businesses, partnerships and markets have faltered. As the algorithms elevate the more contentious content and more contentious scenarios played out with the bubble beginning to implode, social media around the cannabis industry is feeling more like a carbon fiber plated tube thousands of feet below its operating depth on a mission to view the sunken ship of a industry that could have been, only to implode before viewing the wreckage. Instead, many with some harboring resentments towards the current state get high by hiding behind anonymous accounts and picking apart with perverse humor the failed state still dressed up like a lipstick smattered pig. It wouldn’t be honest if I didn’t admit that my participation in this trend has been less than superfluous. I understand fully the small wins of highlighting the skullduggery with a post that warrants a painful laugh. I also know that posting a weed pic just gets you in trouble and as much as I would prefer to post cannabis pics, the drama always brings more conversation and engagement. It becomes a hard pinning role and leaves little room for mobility out of that position and the cost of cashing in for the engagement by low key trauma posting through targeting memes can limit how and who you will work with in the future. People just trucking through the noise with a ten year plan have little time to even look at the drama, but we cannot argue that social media is an effective weapon. I am just not sure that any of us have really earned the power to wield it and are free enough from our own bullshit to be the moral adjudicator of the cannabis space. This includes myself. Most here will just hustle that engagement for a profit, and in the end aren’t too far from the true intentions of law enforcement carrying on with a publicly traded weed company spouting cheap virtue aphorisms on justice. It’s really just a lot of spin encased in a virtual drug. Meanwhile the rappers and duffle bag boys keep grifting away to consumers who just want cheap or hype weed, never to be accepted by their peers who know and have felt their unscrupulous behavior, but without a doubt are still catching the bag for how much longer, I do not know. In any event, troll trauma posting is getting old and it’s time to start developing a new form of market creation and competition. These social low points are always the womb for new waves of creativity. Just make sure that you vet your corporate sponsors. This last point I know is a hard ask. There is much that is not functioning and when the losses keep stacking up an easy win is there with some online character assassination. My argument is that this trend will also lose its relationship with reality, where drama will be engineered to drive engagement. Trolling for some sort of change or awareness will just end up as a marketing strategy solely. Losing its power, like most things do, into the void of short term profitability. The muddy banks of an emerging industry held like a social experiment by the federal government, measuring whether they open up the market through descheduling or limiting its legal expansion by rescheduling within the world of big tobacco and pharmaceuticals, will use what we have created as a reference point for that decision. We still live under a master and they continue to act as one as long as we continue to buy what they sell. Right now, biotech companies and private equity are investing heavily in low THC genetically modified cannabis plants as a substitute for tobacco. I’m not sure how that will work, since nicotine is a far different stimulant and its legal yet regulated proliferation has almost fully negated the awareness and intentional use of its neurotrophic medical benefits that could be used in substitution of antidepressants and SSRIs. Like tobacco, will we lose the purposeful use of cannabis and its medical benefits while these Optimus Prime level industry actors descend into the chaos of the current state? I think it’s likely as more and more of reality continues to play out like the Twilight Zone. We can still resist this by continuing to organize into small thoughtful online groups, perhaps trolling more the meta than the individuals, unless of course the meta becomes an individual. A larger than life icon with the power to determine the industry trajectory as a whole, conspicuously breaking all the rules and continuing to get a pass from the powers that be. Those entities, icons, or organizations, should continue to be tested. As any power should be that could shape the future of our collective and individual dreams. They determine who or who doesn’t sit at the table, and that is also a power that is too great for one or a few, because in the end that power rules over them more than they rule over anything else, bringing forth a primal state of behavior. Behaviors that bury its passengers leagues under a weighted sea, shoddily wrapped in a glossy material that screams hubris.

https://hightimes.com/

Big Pharma Drug Makers Fined Over $82B in Violations Last Decade, Report Shows

It’s time for Big Pharma companies that were caught lying to the public to pay up.  A new report compiled by ConsumerShield suggests the past decade was defined by record-high settlements and penalties in the pharmaceuticals sector, totalling over $80 billion in fines and penalties. ConsumerShield’s report, “The Pharmaceutical Industry: Balancing Profits, Penalties, and Public Safety,” was published on Oct. 17, and it shows that the lion’s share of violations involve synthetic opioids that clearly cause dependence and are powerful enough to stop breathing. London Loves Business reports that the study shows that since 2010, the pharmaceutical industry has incurred $82.8 billion in penalties during over 500 instances of recorded violations due to drug and medical device safety non-observance, unapproved promotion of medical products, breaches of the False Claims Act, and other violations. The biggest culprit—Johnson & Johnson—clocked in with over 45 violation records during the study period, leading to a total of  $24.5 billion in penalties. Johnson & Johnson paid $18 billion USD in penalties over the past five years in opioid and talc cases alone. Next is Teva Pharmaceuticals with penalties of $8.5 billion, AbbVie with penalties of $7.1 billion, GSK plc with penalties of $5.6 billion, and Pfizer with penalties of $3.2 billion. The report also lists significant settlements, with one case standing out: the Purdue Pharma case, resulting in an order to pay $8.3 billion. On Oct. 21, 2020, the Department of Justice announced a massive fine culminating its criminal and civil investigations into the opioid manufacturer Purdue Pharma, and a civil resolution of its civil investigation into individual shareholders from the Sackler family.   Purdue and the Sacklers continued to market OxyContin and opioid products to over 100 health care providers despite the company knowing there was good reason to believe they were diverting opioids and reporting misleading information to the DEA to boost Purdue’s manufacturing quotas.  Hundreds of thousands of people overdosed and died in the process. Nearly 88% of opioid-involved overdose deaths involved synthetic opioids, and opioids were the cause of 80,411 overdose deaths in 2021—75.4% of all drug overdose deaths, the CDC reported in 2021 when overdoses peaked. Compare that to heroin overdoses, which caused just 9,000 overdoses in 2021 unless they were mixed with opioids. Almost ten times more OD’d on synthetic opioids. “The abuse and diversion of prescription opioids has contributed to a national tragedy of addiction and deaths, in addition to those caused by illicit street opioids,” said Deputy Attorney General Jeffrey A. Rosen.  “With criminal guilty pleas, a federal settlement of more than $8 billion, and the dissolution of a company and repurposing its assets entirely for the public’s benefit, the resolution in today’s announcement re-affirms that the Department of Justice will not relent in its multi-pronged efforts to combat the opioids crisis.” Most of us know about the ravages of the opioid epidemic, but what’s the deal with talc? Pharmaceuticals can kill you in other ways. Talcum powder lawsuits claim consumers were diagnosed with cancer after using talc-based Johnson & Johnson baby powder. The ConsumerShield report kicks off with a solemn warning: “It is with a sense of urgency and responsibility that we delve deep into the prevailing paradigms of the pharma industry,” the report reads. “Our investigation is geared towards understanding whether the soaring profits are inadvertently overshadowing the paramount need for consumer safety, ethical promotions, and pioneering research initiatives. “The stark discrepancy between R&D investments and marketing expenditures, coupled with the persistence of unethical practices despite soaring penalties, necessitates a comprehensive examination of the industry’s commitment to ethical practices and consumer well-being.” ConsumerShield representatives say that what the data shows is disturbing. “The juxtaposition of soaring revenues and escalating penalties is alarming,” ConsumerShield Senior Analyst Jane Doe told London Loves Business. “But what’s even more disturbing is the obvious disparity between companies’ spending on research and development (R&D) and their enormous marketing budgets.” The False Claims Act is the federal government’s primary litigation tool in combating fraud against the government, and part of that includes consumer protections. “Pharmaceutical companies that have engaged in illegal off-label marketing or promotion of their drugs have paid the Government hundreds of millions of dollars as a result of Federal False Claims Act cases, often times brought by pharmaceutical sales representatives, sales managers, compliance officers, other pharmaceutical company employees, physicians, nurses and/or employees of hospitals or physician practices,” the False Claims Act Pharmaceutical Fraud summary reads. The report shows the repercussions of marketing opioids despite receiving warnings about its enormous deadly impact, notwithstanding the people who actually need opioids to deal with high levels of pain.

https://hightimes.com/

Roland Griffiths, Pioneer of Johns Hopkins Psilocybin Studies Dead at 77

A Johns Hopkins professor who championed groundbreaking new research into psychedelic substances passed away Monday from colon cancer at the age of 77. Dr. Roland Redmond Griffiths, according to a New York Times obituary, helped usher in a new era of psychedelic research during his time at Johns Hopkins by leading several studies regarding the ways in which psychedelic substances may help combat a myriad of mental health disorders.  Dr. Griffiths’ 2006 paper “Psilocybin Can Occasion Mystical-Type Experiences Having Substantial and Sustained Personal Meaning and Spiritual Significance” was a first-of-its-kind study in which otherwise healthy adults were administered psilocybin in a controlled environment. 80 percent of the participants described their experience as “mystical,” that is holding the same weight or significance as the birth of a child or the death of a parent or an otherwise monumental life event. These effects lasted as long as years in some of the study participants, many of whom were interviewed by well-known author and advocate of psychedelics, Michael Pollan, for his book How to Change Your Mind, which was later adopted into a Netflix series. “Roland had such a sterling reputation as being a rigorous and conscientious scientist,” Pollan said in a phone interview with the New York Times. “No one of his stature had stepped into this area in such a long time that it gave a lot of other people confidence,” he added. “When he presented this completely weird study, which was so out there for science, it could have been dumped on, but it wasn’t.” The double-blind placebo-controlled study served as a baseline for dozens of subsequent studies on psychedelic substances, all of which have pretty poignantly indicated that psychedelics can potentially have massive, overwhelmingly positive effects on human beings. A cursory search of the phrase “psilocybin study” on High Times online will display dozens of studies showing promising results in psychedelic treatment for everything from depression to alcoholism, cigarette smoking, PTSD and more, almost none of which would have been possible without Dr. Griffiths’ initial work with psilocybin at Johns Hopkins. As one of the leading universities in the nation on medical research, it was easier to get approval there than it may have been elsewhere.  Dr. Griffiths’ work with psychedelic medicines continued from there with a study in which cancer patients receiving end-of-life care who were suffering from the anxiety of facing their own deaths were administered psilocybin. He received his own cancer diagnosis in 2021 and told the New York Times Magazine he opted to take a large dose of LSD for the purpose of exploring his cancer diagnosis and asking the cancer, point blank, if it was going to kill him. “The answer was, ‘Yes, you will die, but everything is absolutely perfect; there’s meaning and purpose to this that goes beyond your understanding, but how you’re managing that is exactly how you should manage it,’” Dr. Griffiths said to the New York Times Magazine. “Western materialism says the switch gets turned off and that’s it, but there are so many other descriptions. It could be a beginning! Wouldn’t that be amazing.” According to the New York Times obituary, Dr. Griffiths was born July 19, 1946 in Glen Cove, New York to parents William and Sylvie Griffiths. He received his education at Occidental College in Los Angeles where he majored in psychology and at the University of Minnesota where he studied psychopharmacology. He received his doctorate degree in 1972, after which he was hired by Johns Hopkins University where his research focused on drug use and addiction. Dr. Griffiths authored and contributed to several other studies related to drug use during his time at Johns Hopkins, including a widely-circulated study on caffeine addiction in the early 90’s which was the first to describe chronic caffeine use as similar to if not the same as classical forms of addiction. Dr. Griffiths’ research on caffeine was among the first to show that it could be considered an addictive substance with uncomfortable and unpleasant withdrawals and that caffeine addiction was a “clinically meaningful disorder.” Dr. Griffiths also contributed work to studies on opiate use, cocaine, nicotine and more.  Dr. Griffiths is survived by his wife, Marla Weiner, as well as his three children, five grandchildren and two siblings. At the time of his death, the New York Times said he was working on a paper based on another study where priests and other members of religious orders were given high doses of psilocybin to see if the experience could affect the deeply religious in similar ways as it had the subjects in his previous studies. “A hallmark feature of these experiences is that we’re all in this together,” Dr. Griffiths said in an interview with the Chronicle of Higher Education earlier this year. “It opens people up to this sense that we have a commonality and that we need to take care of each other.”

https://hightimes.com/

Old, Unused Lumber Facility in Minnesota Set To Become Cannabis Cultivation, Manufacturing Facility

One company called HWY35, LLC, currently based in Missouri, recently received funds from the Minnesota Department of Iron Range Resources and Rehabilitation’s Advisory board (IRRR) voted 5-3 to approve a loan to be used to build a cannabis cultivation and manufacturing site in Grand Rapids, Minnesota. The department’s goal is “…to invest in resources to foster vibrant growth and economic prosperity in northeastern Minnesota by enhancing livable communities, maximizing collaborations and partnerships and strengthen businesses and worker education.” It provides low or no interest loans and grants to businesses who plan to relocate into Minnesota, or are currently based in the state and are seeking to expand. The department recently approved a $10 million loan for HWY35 to build a cannabis grow and manufacturing facility in Grand Rapids. “While launching the cultivation and manufacture of cannabis products as a new industry in the state of Minnesota is exciting, the opportunity to create positive economic impacts in northeastern Minnesota and, in particular the Grand Rapids and greater Iron Range communities, for generations to come is both thrilling and rewarding,” said HWY35 Lead Minnesota Investment Partner, John Hyduke. “We will revitalize the 138-acre former Ainsworth site into a high-tech, state-of-the-art, cannabis cultivation and manufacturing facility that our communities will be proud of and that will serve as an industry leader for the state of Minnesota.” According to Rob Mattei, City of Grand Rapids Director of Community Development, HWY35 has exhibited great success in operating cannabis facilities in similar states as well, which is why their proposal was approved. The property was once home to Canada-based Ainsworth Lumber Company, which made oriented strand boards used in single-family home construction. The company initially bought the Grand Rapids location in 2004, which it sat idle as of 2006, and closed permanently in 2008. According to the Grand Rapids Herald Review, the house market was part of the reason for the closure. At its peak, 190 people were employed at the facility. HWY35 on the other hand estimates it will create hundreds of new jobs with its cannabis business, according to IRR Commissioner Ida Rukavina. “The HWY35 project is expected to benefit northeastern Minnesota through the creation of 400 jobs and increased tax revenues that can be reinvested back into the region,” Rukavina said. “Because the project is based in both manufacturing and agriculture, it has the potential to significantly diversify the local economy, which is one of our agency’s primary goals.” According to MPR News, the jobs will pay an average of $24 an hour, and offer a range of salaries between $40,000 to $160,00 per year. HWY35’s licenses are not in hand yet, but IRRR director of business development, Mathew Sjoberg, said that they should be up and operating by the end of 2024. Rukavina told MPR News that approving cannabis in the area will help add diversity to the region’s industries, mainly mining and timber. “We know that not everyone may agree with this type of industry,” said Rukavina. “But it is now legal in the state of Minnesota. This type of manufacturing, if it doesn’t happen here, it is going to happen somewhere else in our state.” The IRR and HWY35 came to the agreement that $5 million of the loan will be forgiven if the company can reach 150 employees within five years, or 175 employees within the next 10 years. Of course, there is traditionally opposition from some parties regarding the growth of cannabis in a new market. Minnesota Rep. Ben Davis said that he used cannabis in his youth, and claims that it is addictive. “I’m absolutely for free market capitalism,” said Davis. “But that does not mean I need to put my stamp of approval on us taking $10 million of people’s money, of government money, and putting it towards basically subsidizing this industry.” Sen. Justin Eichorn also opposed the public financing support, and said that the public should have been able to voice their opinion about how the money was being used. “I’m surprised it’s going to take darn near 33 percent of the total project cost and government money to get this thing off the ground, based on conversations I had with other people that are in the industry and other states,” Eichorn said. HWY35’s IRRR loan application stated that this was a “remarkable market opportunity,” and that “industry is poised for explosive growth, offering an unprecedented chance for HWY35 to become a dominant force in the emerging market.” Recreational cannabis is new in Minnesota, thanks to Gov. Tim Walz signing a cannabis legalization bill in May. “We’ve known for too long that prohibiting the use of cannabis hasn’t worked. By legalizing adult-use cannabis, we’re expanding our economy, creating jobs, and regulating the industry to keep Minnesotans safe,” Walz said. “Legalizing adult-use cannabis and expunging or resentencing cannabis convictions will strengthen communities. This is the right move for Minnesota.” The program began on Aug. 1, but dispensaries won’t be ready for at least a couple of years.

https://hightimes.com/

Harlem’s First Dispensary Opens to Customers

After months of controversy and legal disputes, the first legal cannabis dispensary in Harlem opened its doors to customers on Wednesday.  Gotham Buds celebrated its grand opening on West 125th Street in Manhattan –– just across the street from the historic Apollo Theater.  According to CBS New York, the store is the “the 26th conditional adult-use retail dispensary to open in New York State,” as well as the first state-licensed dispensary to open in the iconic neighborhood with a rich history of music and the arts. It has been a long road to opening for Gotham Buds, marked by fits and starts.  A local business group, the 125th Street Business Improvement District, filed a lawsuit in April challenging the opening of the shop, contending that “the process was conducted secretly in order to avoid opposition from the community.” The group also raised concerns about the cannabis store’s location relative to a neighborhood school. “We’ve taken this action to really create transparency and to create a channel of communication to understand why this location,” Mukaram Taheraly, the chairman of the 125th Street Business Improvement District, said then. Barbara Askins, president of the 125th Street Business Improvement District, said that the group believes “this location is bad for our children.”  But the lawsuit was dismissed in August after a “judge ruled the business across from the Apollo Theatre is exempt from an injunction blocking the Office of Cannabis Management from opening any other dispensaries while a lawsuit proceeds against its licensing program,” according to CBS New York. The judge’s ruling set the stage for a grand opening that was tentatively scheduled for September 5, but the date was ultimately kicked to this week. “Harlem isn’t just our location — it’s our community, our commitment. We’re here to grow roots and become a pillar of dreams realized,” Jeffrey Lopez, an owner of Gotham Buds, said in a statement, as quoted by the New York Daily News. “It’s all about passion, vision and a purpose bigger than ourselves.” The state’s allocation of recreational cannabis dispensary licenses has drawn other legal challenges, too. In August, a New York judge slapped an injunction on the process, temporarily pausing the awarding of licenses after a lawsuit was filed by a group of veterans. The veterans challenged the state’s policy of awarding the first round of licenses to individuals with prior pot-related convictions.  That policy was announced last year by New York Gov. Kathy Hochul. “New York State is making history, launching a first-of-its-kind approach to the cannabis industry that takes a major step forward in righting the wrongs of the past,” Hochul said in her announcement of the initiative. “The regulations advanced by the Cannabis Control Board today will prioritize local farmers and entrepreneurs, creating jobs and opportunity for communities that have been left out and left behind. I’m proud New York will be a national model for the safe, equitable and inclusive industry we are now building.” According to the Daily News, the judge who heard the veterans’ case “ruled that the state’s Office of Cannabis Management had failed to comply with the court, undoing the exemption and leaving shops like Gotham Buds in limbo,” but that, “in yet another twist, Gotham Buds and four other dispensaries were cleared to open.” More from the Daily News on Gotham Buds’ opening: “Gotham Buds is now one of 11 legal pot shops in the five boroughs. However, there are thousands of unlicensed shops in the city that have ducked state rules and regulations to sell their ganja. The injunction was not the only hurdle the Harlem store had to jump through. Earlier this year, the dispensary faced intense community backlash and was slapped with a lawsuit from a local group of businesses who said the shop would attract crime, add to congestion and encourage drug use in an area already plagued with all three. The application window for nonconditional cannabis business licenses — for the general public — opened on Oct. 4 and will remain open until early December. The newly expanded program will take applications for new retail shops, farms, processing plants and microbusinesses.” More than two years after New York legalized recreational cannabis for adults, the new legal weed market continues to take shape.  The law was enacted by former New York Gov. Andrew Cuomo. After Cuomo stepped down amid allegations of sexual misconduct, he was succeeded by Hochul, who went right to work in getting the legal weed market up and running.  Adult-use cannabis sales officially began in December, when the state’s first legal dispensary opened in Manhattan’s East Village neighborhood. “We set a course just nine months ago to start New York’s adult-use cannabis market off on the right foot by prioritizing equity, and now, we’re fulfilling that goal,” Hochul said in a statement at the time. “The industry will continue to grow from here, creating inclusive opportunity in every corner of New York State with revenues directed to our schools and revitalizing communities.”

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